PTSD Trial, Recruiting NCT04437498 Sponsor: VA Office of Research and Development Condition: PTSD
Back to Ptsd

PTSD Trial, Recruiting

NCT04437498
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are veterans and have both a mild traumatic brain injury (a type of head injury, sometimes called mTBI) and post-traumatic stress disorder (PTSD)

Who may not be able to join:

  • People whose memory loss after the head injury lasted longer than 24 hours
  • People who scored below 13 on a standard scale used to measure consciousness (called the Glasgow Coma Scale) more than 30 minutes after the injury
  • People who were unconscious for more than 30 minutes after the injury
  • People with a positive pregnancy test
  • People who have meningitis or a neurological (brain or nervous system) condition other than the mild traumatic brain injury
  • People who have had a diagnosed alcohol or substance use disorder in the past 12 months, based on a structured clinical interview
  • People with a current or past diagnosis of schizophrenia, schizoaffective disorder, bipolar disorder, anorexia nervosa, or bulimia, based on a structured clinical interview
  • People who are currently having active thoughts of suicide
  • People who have a history of serious medical or neurological illness, such as heart, digestive, liver, kidney, or other significant health conditions
  • People who are currently being treated with antipsychotic medications, opioids, or benzodiazepines (a type of sedative or anxiety medication)
  • People whose brain scans (MRI or CT) show a physical or structural abnormality in the brain

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Doug J Bremner, MD, Atlanta VA Medical and Rehab Center, Decatur, GA

Phone: (404) 712-9569

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
25 February 2021
Est. completion
10 December 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

CAPS; insula; HVLT-R % retention; Change in IL6 Concentration in Blood with Stress; hippocampal activation

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov