All conditions

PTSD

Plain English clinical trial information, updated daily from ClinicalTrials.gov and public government registries. Not medical advice.

2343
Trials on record
368
Recruiting now
4
Australian sites
14
Phase 3 trials
How these figures are counted
  • Trials on record is every trial tagged to this condition at any stage, except those withdrawn before starting or terminated early. Most are completed rather than ongoing, so this is a measure of research history, not of current activity. It is also smaller than the sitewide "trials tracked" figure, which does include withdrawn and terminated trials.
  • Recruiting now counts only trials whose registry status is "Recruiting". Trials listed as not yet recruiting or enrolling by invitation are excluded, so this understates how many may open to new participants soon.
  • Australian sites counts trials counted under "Recruiting now" that list at least one Australian site. A site being listed does not mean it is currently enrolling, and Australian trials registered only on ANZCTR are not counted yet, so this understates local availability.
  • Phase 3 trials counts trials counted under "Recruiting now" that are at Phase 3.

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Voxsanity currently covers 103 conditions. We are expanding coverage regularly.

Understanding PTSD

Post-traumatic stress disorder, or PTSD, is a mental health condition that can develop after a person experiences or witnesses a traumatic event. This might include things like a serious accident, natural disaster, assault, combat, or the sudden loss of someone close. After trauma, it is normal to feel shaken, anxious, or on edge for a short time. With PTSD, however, these feelings do not fade in the usual way. A person might find themselves reliving the event through flashbacks or nightmares, avoiding places or situations that remind them of what happened, feeling emotionally numb or disconnected, or being in a constant state of alertness as though danger is still present. These experiences can make everyday life feel very difficult.

PTSD is more common in Australia than many people realise. Research suggests that around 12% of Australians will experience PTSD at some point in their lives. It can affect anyone — veterans, emergency service workers, survivors of abuse or accidents, and people who have been through natural disasters, among others. It is also worth knowing that carers and family members supporting someone with PTSD can find this genuinely hard, and that is a completely understandable response.

The good news is that PTSD is a recognised and treatable condition. Healthcare professionals in Australia generally have access to a range of evidence-based approaches, which typically include talking therapies and, in some cases, medication. Treatment is usually tailored to the individual, and many people do see significant improvement with the right support. Organisations like Phoenix Australia and Beyond Blue offer reliable information, and a GP is often a good first point of contact for understanding what options might be available.

This overview is an AI generated summary written from public medical sources and checked on a sample basis. It is general information, not medical advice or a diagnosis. Always speak with your doctor about your situation. How we use AI

Can you access treatment for PTSD in Australia right now? Here's what's publicly known.

Information on this site does not constitute medical advice. Data is sourced from publicly available government registries. Always consult your doctor before making any health decisions. Trial status should be verified directly with the trial site.

Updated regularly from public government registries

Research pipeline

Where trials for PTSD currently sit in the development pipeline. The funnel shape shows how few drugs reach later phases in general; the counts are this condition's actual trial numbers.

Phase success rates are industry-wide historical averages, not predictions for specific trials. Learn how trials work →

Most active research sponsors

Organisations with the most recruiting trials for PTSD.

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Where trials are running

Clinical trial sites for PTSD by country. Australia is highlighted.

Showing the top 10 of 34 countries with trial sites.

If you need support right now

Voxsanity is not an emergency or crisis service, and this page is not medical advice. If you or someone else is in immediate danger, call 000. Australian crisis support lines are below. If you are outside Australia, see our helpful links page for support in your country.

  • Lifeline (24/7 crisis support): 13 11 14
  • Beyond Blue: 1300 22 4636
  • 13YARN (Aboriginal & Torres Strait Islander crisis support, 24/7): 13 92 76
  • Suicide Call Back Service: 1300 659 467
  • SANE Australia: 1800 187 263
  • Emergency: 000

Find a service or provider through official directories:

Questions you could bring to a GP or specialist:

  • What are the treatment options for my situation, and what does each involve?
  • Is a clinical trial something worth considering for me, and how would I be assessed for one?
  • What support is available while I wait for an appointment or a decision?

Clinical trials for PTSD

Showing 368 of 368 trials

The plain English eligibility text on each trial below is an AI generated summary of the official criteria, checked on a sample basis. How we use AI

🇦🇺 NCT06175104 · Children's Hospital Medical Center, Cincinnati Not Applicable · 2 countries Recruiting
Recruiting Not Applicable Est. completion 1 December 2026
🇦🇺 AU🇺🇸 US

**Who might be able to join this trial:** - The pregnancy involves a baby diagnosed with a heart condition where only one of the heart's two main pumping chambers has developed properly (called single ventricle congenital heart disease). - This heart condition was identified between 16 and 30 weeks of pregnancy. - The...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
🇦🇺 NCT06412757 · Deakin University Phase 3 · 1 country Recruiting
Recruiting Phase 3 Est. completion 1 May 2027
🇦🇺 AU

**Who might be able to join this trial:** - People aged 18 years or older. - People who are fluent in English. - People who have been assessed as meeting the clinical diagnosis of PTSD (Post-Traumatic Stress Disorder) according to a standard diagnostic interview. - People whose PTSD symptom score on a standard checklis...

Phase 3: ~65% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
🇦🇺 NCT07280065 · Senseye, Inc. Phase 3 · 2 countries Recruiting
Recruiting Phase 3 Est. completion 1 October 2026
🇦🇺 AU🇺🇸 US

**Who might be able to join this trial:** - People who are willing and able to read, understand, and sign a consent form agreeing to take part - People aged 18 or older - People who, in the past month, have experienced at least one of the following: nightmares or unwanted, intrusive thoughts; avoiding certain thoughts...

Phase 3: ~65% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
🇦🇺 NCT07499440 · HB BioTech, LLC Phase 2 · 1 country Recruiting
Recruiting Phase 2 Est. completion 1 September 2027
🇦🇺 AU

Who might be able to join this trial: - People aged 18 to 65 years old at the time of giving consent to participate - People who have been diagnosed with PTSD according to standard diagnostic guidelines (DSM-5) - People whose PTSD symptoms reach a minimum required severity level, based on a standard clinical assessment...

Phase 2: ~30% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT01327690 · Soul Medicine Institute Early Phase 1 · 1 country Recruiting
Recruiting Early Phase 1 Est. completion 31 December 2027
🇺🇸 US

Who might be able to join this trial: - People who are able to follow instructions, fill out written forms, and give informed consent to participate. - People who can read and write in English. - People who are in good physical health. - People who are currently serving in the military, are veterans, or are family memb...

Early Phase 1 studies are small, early exploratory studies that come before the main Phase 1 to 3 testing, so a standard phase success rate does not apply.
NCT01627301 · Emory University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 December 2027
🇺🇸 US

Who might be able to join this trial: - Veterans who have been diagnosed with PTSD and have blood pressure that is either normal or slightly elevated (but not high enough to be diagnosed as high blood pressure) - Veterans who do not have PTSD and have blood pressure that is either normal or slightly elevated (this grou...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT02236377 · University of Tulsa Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 July 2025
🇺🇸 US

Who might be able to join this trial: - You are 18 years of age or older - You have been through a traumatic event (as defined by standard mental health guidelines) - You have been having roughly at least one nightmare per week over the past month - You are able to read and speak English Who may not be able to join: -...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT02443636 · Nova Scotia Health Authority Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 December 2028
🇨🇦 CA

Who might be able to join this trial: - People of any gender who are looking for or already receiving help for mental health-related problems in the maritime provinces of Canada - People who are able to give their own consent to participate, or who have a suitable person (such as a family member or legal guardian) who...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT02560805 · Emory University Phase 2 · 1 country Recruiting
Recruiting Phase 2 Est. completion 30 March 2027
🇺🇸 US

Who might be able to join this trial: - Veterans between the ages of 18 and 65 years old, either with PTSD or without PTSD (the group without PTSD serves as a comparison group, matched by age, gender, and race). Who may not be able to join: - People who are currently pregnant - People who have high blood pressure (hyp...

Phase 2: ~30% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT03170440 · University of Florida Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 October 2025
🇺🇸 US

Who might be able to join this trial: - Veterans who have been diagnosed with PTSD, whether or not they also have a history of mild traumatic brain injury (a mild head injury). Who may not be able to join: - People who have a serious mental health condition that is not related to PTSD or traumatic brain injury. - Peop...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT03642028 · VA Office of Research and Development Phase 4 · 1 country Recruiting
Recruiting Phase 4 Est. completion 31 December 2025
🇺🇸 US

**Who might be able to join this trial:** - You are a man or woman between 18 and 75 years old with a history of serving in the U.S. military, can read and understand English, and are able to sign a consent form - You have experienced a traumatic event that meets the official definition used to diagnose PTSD - You have...

Phase 4 trials study a drug that has already been approved, monitoring long-term safety and effectiveness in real-world use.
NCT03667846 · NYU Langone Health Phase 2 · 1 country Recruiting
Recruiting Phase 2 Est. completion 31 August 2025
🇺🇸 US

**Who might be able to join this trial:** - People between 18 and 70 years old (any gender) - People who have been diagnosed with moderate or severe Alcohol Use Disorder (a problematic pattern of drinking) based on a structured clinical interview - People who want to cut down or stop drinking - People who have had at...

Phase 2: ~30% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT03755401 · Montefiore Medical Center Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 May 2027
🇺🇸 US

Who might be able to join this trial: - People with moderate PTSD, measured by a specific assessment tool called the CAPS with a score above 40 - People who have a history with one of two specific talking therapies (CPT or PE) — meaning they were offered the therapy but said no, they started but did not finish, their t...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT03803332 · Weill Medical College of Cornell University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 March 2027
🇺🇸 US

**Who might be able to join this trial:** - People who speak English - People who have experienced actual or threatened sexual violence during military service (from the Vietnam era through to more recent conflicts including Operation Iraqi Freedom, Operation Enduring Freedom, and Operation New Dawn) - People who have...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT03819608 · Northwestern University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 December 2026
🇺🇸 US

**Who might be able to join this trial:** - People who are between 18 and 80 years of age - People who are at least 3 months past the event that caused their mild traumatic brain injury (mTBI) - People who have a confirmed history of mild traumatic brain injury, either with or without PTSD, as determined through speci...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT03887559 · St. Olavs Hospital Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 June 2026
🇳🇴 NO

**Who might be able to join this trial:** - You are currently receiving care at a regular outpatient clinic (not a hospital stay). - You have experienced or witnessed one or more deeply distressing or traumatic events, as measured by a screening questionnaire. - You are experiencing symptoms related to trauma, such as...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT03932773 · The University of Texas at Dallas Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 July 2026
🇺🇸 US

**Who might be able to join this trial:** - People who served in the military in conflicts that took place after September 11, 2001. - People who have been formally diagnosed with PTSD (post-traumatic stress disorder) linked to combat experiences in those post-9/11 conflicts, based on a specific clinical assessment cal...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT04130269 · Medical University of Graz Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 7 December 2027
🇦🇹 AT

Who might be able to join this trial: - You are willing to take part in the study - You are a man or woman between the ages of 19 and 90 - You have previously had a heart attack - You did not have a psychiatric (mental health) condition before your heart attack - You do not have another serious illness that affects you...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT04152993 · VA Greater Los Angeles Healthcare System Early Phase 1 · 1 country Recruiting
Recruiting Early Phase 1 Est. completion 31 July 2026
🇺🇸 US

**Who might be able to join this trial:** - Men between the ages of 25 and 60 years old - People who are able to give informed consent according to the study's institutional policies and take part in a 4-year follow-up program that includes assessments and device adjustments - People whose psychiatric medication has r...

Early Phase 1 studies are small, early exploratory studies that come before the main Phase 1 to 3 testing, so a standard phase success rate does not apply.
NCT04180930 · U.S. Army Medical Research and Development Command Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 June 2025
🇺🇸 US

Who might be able to join this trial: - People who are currently serving in the military or are military veterans, aged 18 or older - People who are able to understand and agree to participate in the study on their own - People who have experienced at least one seriously distressing or traumatic event (such as those li...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT04276922 · University of Colorado, Denver Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 December 2024
🇺🇸 US

Who might be able to join this trial: - You work as a healthcare provider (such as a doctor, nurse, or similar role) mainly in a hospital setting for at least 20 hours per week. - You show signs of burnout based on a specific questionnaire called the Maslach Burnout Inventory (MBI), meaning you scored above a certain l...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT04426448 · University of Botswana Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 August 2025
Botswana

Who might be able to join this trial: - You are able to understand and communicate in either Setswana or English - You have been diagnosed with a serious mental illness (SMI) such as schizophrenia, schizophreniform disorder, schizoaffective disorder, bipolar disorder, or severe depression, based on standard diagnostic...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT04437498 · VA Office of Research and Development Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 10 December 2026
🇺🇸 US

**Who might be able to join this trial:** - People who are veterans and have both a mild traumatic brain injury (a type of head injury, sometimes called mTBI) and post-traumatic stress disorder (PTSD) **Who may not be able to join:** - People whose memory loss after the head injury lasted longer than 24 hours - People...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT04452500 · VA Office of Research and Development Phase 2 · 1 country Recruiting
Recruiting Phase 2 Est. completion 31 December 2026
🇺🇸 US

**Who might be able to join this trial:** - People who have served in the US military - People who can read and understand English - People who are able to give written consent to participate - People with PTSD symptoms severe enough to score 23 or higher on a specific PTSD assessment called the CAPS-5, given at the s...

Phase 2: ~30% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT04512755 · Advanced Integrative Medical Science Institute Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 July 2025
🇺🇸 US

**Who might be able to join this trial:** - You are a new patient having your first appointment (either in-person or by telemedicine) with a doctor or advanced practice provider at AIMS. - You are an existing patient already receiving care at AIMS. - If you are 18 or older, you are able to understand how the study work...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT04529031 · University of California, Los Angeles Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 28 December 2027
🇺🇸 US

Who might be able to join this trial: - Children who have been diagnosed with PTSD (Post-Traumatic Stress Disorder), confirmed by medical records - Children between the ages of 11 and 15 years old - Children who are able to read and write in English Who may not be able to join: - Children who have an intellectual disa...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT04550377 · NYU Langone Health Phase 2 · 1 country Recruiting
Recruiting Phase 2 Est. completion 1 March 2026
🇺🇸 US

**Who might be able to join this trial:** - People who have been diagnosed with Post-Traumatic Stress Disorder (PTSD), confirmed through a specific clinical assessment tool called the CAPS-5. - People who have had a mild traumatic brain injury (TBI), confirmed through specific screening tools — this applies only to pa...

Phase 2: ~30% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT04558112 · University of Wisconsin, Madison Phase 2 · 1 country Recruiting
Recruiting Phase 2 Est. completion 1 December 2023
🇺🇸 US

**Who might be able to join this trial:** - People who have a current diagnosis of PTSD where the traumatic event involved physical or sexual assault - People who speak English - People who are in general good health **Who may not be able to join:** - People who have metal objects inside their body, such as surgical i...

Phase 2: ~30% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT04585685 · Christal L Badour Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 November 2026
🇺🇸 US

**Who might be able to join this trial:** - People who have experienced sexual trauma and currently meet the diagnostic criteria for PTSD, confirmed through specific assessment tools used by the trial (confirm with trial site) - People who are currently experiencing trauma-related feelings of mental "dirtiness" or con...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT04626050 · Weill Medical College of Cornell University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 January 2028
🇺🇸 US

Who might be able to join this trial: - People who work in healthcare in any role (such as doctors, nurses, or support staff) and have experienced trauma related to their work - People who speak English - People who are 18 years of age or older - People who are medically stable at the time of the trial - People who are...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT04670640 · Emory University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 March 2027
🇺🇸 US

Who might be able to join this trial: - People who have experienced at least one traumatic event that meets a specific clinical definition of trauma (assessed using a checklist of life events) - People who score 7 or higher on a standardised scale that measures feelings of depersonalisation (a sense of feeling detached...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT04672551 · University of Zurich Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 November 2027
🇨🇭 CH

**Who might be able to join this trial:** - People between 18 and 70 years of age - Men or women are eligible - People who have had a heart attack (either with specific electrical changes on a heart tracing called ST-elevation, or confirmed by a blood protein marker called troponin), as confirmed by a heart specialist...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT04701723 · Centre Hospitalier Universitaire de la Réunion Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 May 2027
Reunion

**Who might be able to join this trial:** - People who have been seen at a medico-psychological emergency unit - People who have been diagnosed with acute stress disorder according to the DSM-5 (a standard medical classification system) - People who experienced or witnessed a potentially traumatic event between 3 and 1...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT04752618 · New York University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 April 2027
🇺🇸 US

**Who might be able to join this trial:** **For mothers:** - People who are already receiving preventive services at the time they are asked to take part in the study - People who score 28 or higher on a PTSD symptom scale, or who meet the standard diagnostic criteria for PTSD (confirm with trial site) - People who ha...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT04770584 · The University of Texas Health Science Center, Houston Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 January 2028
🇺🇸 US

Who might be able to join this trial: - People aged 18 to 70 years old, of any gender - People with a current diagnosis of PTSD (for the PTSD group) - People who have experienced trauma but have no current mental health (psychiatric) disorders and no current PTSD (for the trauma-exposed healthy control group) - People...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT04793776 · VA Office of Research and Development Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 October 2026
🇺🇸 US

**Who might be able to join this trial:** - You are a male or female Veteran who was deployed to a combat zone after September 11, 2001. - You currently have full or significant symptoms of PTSD, as confirmed by a clinical assessment. - You have had at least 3 aggressive incidents in the past month (such as yelling, th...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT04801589 · Vanderbilt University Medical Center Phase 3 · 1 country Recruiting
Recruiting Phase 3 Est. completion 17 April 2026
🇺🇸 US

**Who might be able to join this trial:** - Children aged from 44 weeks post-menstrual age (a measure used for premature babies) up to 11 years old (confirm with trial site if unsure how age is calculated) - Children who are planned to be admitted to the pediatric ICU at Monroe Carell Jr. Children's Hospital at Vanderb...

Phase 3: ~65% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT04852744 · University Hospital, Caen Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 December 2027
🇫🇷 FR

**Who might be able to join this trial:** - The participant is female and between 13 and 17 years old (inclusive) - The participant is able to read and understand French - The participant is enrolled in the French social security system - Both the participant and her legal guardian(s) with parental authority have sign...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT04877093 · Wake Forest University Health Sciences Phase 3 · 1 country Recruiting
Recruiting Phase 3 Est. completion 31 March 2027
🇺🇸 US

**Who might be able to join this trial:** - You are 18 years old or older - You are a U.S. military veteran - You have been diagnosed with PTSD, either by a doctor or confirmed by the study team - Your score on a PTSD symptom checklist (called the PCL-5) is at least 40 - Your PCL-5 scores show a high enough level of c...

Phase 3: ~65% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT04887116 · Weill Medical College of Cornell University Early Phase 1 · 1 country Recruiting
Recruiting Early Phase 1 Est. completion 1 January 2027
🇺🇸 US

**Who might be able to join this trial:** - You are either a COVID-19 patient or a healthcare worker who has experienced trauma related to their job - You speak English - You are 18 years of age or older - You are in a stable enough physical health condition to participate - You have been diagnosed with PTSD or a milde...

Early Phase 1 studies are small, early exploratory studies that come before the main Phase 1 to 3 testing, so a standard phase success rate does not apply.
NCT04911036 · University Hospital, Lille Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 May 2027
🇫🇷 FR

**Who might be able to join this trial:** - You are the mother and/or father of a living child between 12 and 24 months old who had surgery as a newborn for a type 1 or type 3 oesophageal abnormality (a condition where the food pipe did not form correctly) - You have been given information about the study and have not...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT04916327 · Virginia Commonwealth University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 August 2026
🇺🇸 US

Who might be able to join this trial: - People who appear generally healthy and do not have obvious heart, lung, or metabolic conditions (such as diabetes) - For the PTSD group: people who score 33 or higher on a standard PTSD symptom checklist called the PCL-5 - For the anxiety (GAD) group: people who score 10 or high...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT04916340 · Virginia Commonwealth University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 28 December 2026
🇺🇸 US

**Who might be able to join this trial:** - People who appear generally healthy and do not have any obvious heart, lung, or metabolic conditions (such as diabetes) - For the PTSD group: people who score 33 or higher on a standard PTSD symptom checklist called the PCL-5 - For the anxiety (GAD) group: people who score 10...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT04922762 · Virginia Commonwealth University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 December 2026
🇺🇸 US

**Who might be able to join this trial:** - People who appear to be generally healthy and do not have obvious heart, lung, or metabolic conditions (such as diabetes) - People applying for the PTSD group must score 33 or higher on a standard PTSD symptom checklist called the PCL-5 - People applying for the Generalized A...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT04953273 · University Hospital, Lille Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 July 2026
🇫🇷 FR

Who might be able to join this trial: - You are a woman - You are 18 years old or older - You have visited a forensic medicine clinic after experiencing violence - During the violent event, you were exposed to death, a threat of death, serious physical harm, or sexual violence (either actual or threatened) - You have s...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT04959695 · VA Office of Research and Development Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 June 2027
🇺🇸 US

**Who might be able to join this trial:** - People who are veterans between the ages of 18 and 65 - People who are enrolled in VA healthcare and whose treating VA providers consider them eligible for PTSD talk therapy through the VA - People who have a current PTSD diagnosis confirmed by a structured clinical assessmen...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT04985344 · University Hospital, Toulouse Phase 3 · 1 country Recruiting
Recruiting Phase 3 Est. completion 1 September 2027
🇫🇷 FR

**Who might be able to join this trial:** - Children aged 7 to 12 years old - Children who score 40 or above on a specific PTSD symptom questionnaire called the CPTS-RI - Children whose main diagnosis is PTSD, where the traumatic event happened at least 6 months ago - Children with a resting heart rate of 55 beats per...

Phase 3: ~65% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT05065450 · Washington University School of Medicine Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 November 2026
🇺🇸 US

Who might be able to join this trial: - People who can understand and speak English. - People who are able to give their informed consent to take part in research. - People who have been diagnosed with epilepsy. - People who are already scheduled to have long-term brain monitoring using electrodes placed inside the sku...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05086757 · Medical University of South Carolina Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 August 2026
🇺🇸 US

Who might be able to join this trial: - You are a young person between the ages of 12 and 17 who has been admitted to hospital after a traumatic injury - You scored highly on a screening tool used to measure emotional distress experienced around the time of the traumatic event Who may not be able to join: - The injury...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05120635 · Duke University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 June 2026
🇺🇸 US

Who might be able to join this trial: - People who are 18 years of age or older - People who have had depth electrodes or a responsive neurostimulation (RNS) device surgically placed in the brain, either recently or previously, as part of their care - People who are willing to give their agreement to take part in the s...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05147948 · Skane University Hospital Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 18 October 2026
🇸🇪 SE

**Who might be able to join this trial:** - People who score 25 or higher on a standard PTSD symptom scale called the CAPS - People whose trauma came from a single event (rather than repeated events) - People who can understand, read, and write in Swedish - People who have long-term chronic pain that significantly aff...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05149534 · VA Office of Research and Development Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 29 January 2027
🇺🇸 US

**Who might be able to join this trial:** - People who are veterans - People who speak English and are able to give written consent to participate - People who have been diagnosed with PTSD - People who are between 18 and 60 years of age **Who may not be able to join:** - People who have a history of seizures or serio...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05156112 · VA Office of Research and Development Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 May 2027
🇺🇸 US

**Who might be able to join this trial:** - People who have served in the U.S. military, Reserve, or National Guard - People who are at least 18 years old - People whose sleep study results show a certain level of breathing disruptions during sleep (an AHI of 5 or more per hour) - People who have experienced a traumat...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05194930 · VA Office of Research and Development Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 June 2026
🇺🇸 US

**Who might be able to join this trial:** - You are a Veteran living in the community (not in a care facility) and are 18 years of age or older - You have received care from the VA Greater Los Angeles Healthcare System (VAGLAHS) within the past year - You live within 50 miles of the VA Sepulveda Ambulatory Care Center...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05219175 · University of New Mexico Phase 2 · 1 country Recruiting
Recruiting Phase 2 Est. completion 1 April 2027
🇺🇸 US

**Who might be able to join this trial:** - People who are at least 18 years old. - People who have opioid use disorder and are taking daily oral methadone (180 mg or less) or sublingual buprenorphine (24 mg or less), and whose treatment has been considered stable for at least 3 months by their prescriber or medical r...

Phase 2: ~30% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT05244564 · Uniformed Services University of the Health Sciences Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 May 2027
🇺🇸 US

Who might be able to join this trial: - People who are a current or former military service member, retiree, or a family member registered as a DEERS-eligible dependent, who are male or female and at least 18 years old - People who have been diagnosed with PTSD, confirmed through a specific clinical assessment called t...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05267665 · VA Office of Research and Development Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 March 2027
🇺🇸 US

**Who might be able to join this trial:** **For Veterans:** - People who have a current diagnosis of PTSD based on DSM-5 criteria - People who have served in the military (Veteran status) - People who are willing to have a family member involved in the study - People who have recently started, or are in the early stag...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05269459 · University of Nebraska Phase 2 · 1 country Recruiting
Recruiting Phase 2 Est. completion 1 December 2028
🇺🇸 US

**Who might be able to join this trial:** **For all participants:** - You are willing and able to give your consent to take part in the study - You are willing to follow all study procedures and are available for the full length of the study - You are between 21 and 65 years old - You are able to read and communicate...

Phase 2: ~30% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT05310097 · Boston University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 January 2027
🇺🇸 US

Who might be able to join this trial: - People who have been diagnosed with PTSD, confirmed through a structured clinical interview called the Clinician Administered PTSD Scale (based on standard psychiatric guidelines). - People who are taking psychiatric medication, as long as the dose has been stable for the past fo...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05327504 · VA Office of Research and Development Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 12 May 2027
🇺🇸 US

Who might be able to join this trial: - People who are veterans aged 18 years or older - People who have been diagnosed with at least one substance use disorder (a condition where use of alcohol or drugs causes significant problems in a person's life), according to standard diagnostic guidelines (DSM-5) - People who ha...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05331534 · University Hospital, Lille Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 2 February 2028
🇫🇷 FR

**Who might be able to join this trial:** - People who understand and can communicate in French - People who are willing to give their informed consent by dating and signing the study participation form - People who have health insurance coverage - People with normal vision and hearing, or vision and hearing that is f...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05358067 · Centre Hospitalier Arras Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 23 October 2026
🇫🇷 FR

"Who might be able to join this trial: - People who have experienced a traumatic event within the last 48 hours - People who speak French Who may not be able to join: - People who are already taking part in another clinical trial focused on treating the psychological effects of a traumatic experience - People who are...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05368987 · The University of Texas Health Science Center, Houston Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 September 2028
🇺🇸 US

Who might be able to join this trial: - People who are willing and able to give their informed consent to participate. - People who have a current diagnosis of PTSD (for the PTSD group). - People who have no current or past psychiatric disorders (for the healthy volunteer comparison group). Who may not be able to join...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05380050 · VA Office of Research and Development Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 October 2026
🇺🇸 US

**Who might be able to join this trial:** - Veterans who served in the Iraq or Afghanistan wars (OIF, OEF, or OND) and have been diagnosed with both a mild traumatic brain injury (mTBI) and post-traumatic stress disorder (PTSD), based on Veterans' Affairs and Department of Defense guidelines. - People whose most recent...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05421494 · Peking University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 10 June 2024
🇨🇳 CN

**Who might be able to join this trial:** **Study 1:** - Adults between 18 and 65 years old (male or female) - People who have been diagnosed with PTSD or a milder form of PTSD (sometimes called subthreshold PTSD), assessed using a standard interview tool - People currently taking psychiatric medication, provided the...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05423444 · The University of Texas Health Science Center at San Antonio Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 28 February 2027
🇺🇸 US

**Who might be able to join this trial:** - Young people aged 12 to 17 who have reached at least the second stage of puberty - People who have experienced trauma involving another person (such as abuse, violence, or neglect) - People who have had symptoms of PTSD for at least one month, with at least one symptom from e...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05427708 · University of Texas at Austin Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 May 2027
🇺🇸 US

**Who might be able to join this trial:** - People who score 8 or higher on a standard anxiety measurement scale called the OASIS, indicating clinically elevated anxiety. - People who have been diagnosed with one of the following as their primary mental health condition: Generalized Anxiety Disorder, Panic Disorder, He...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05441280 · VA Office of Research and Development Phase 2 · 1 country Recruiting
Recruiting Phase 2 Est. completion 12 July 2027
🇺🇸 US

**Who might be able to join this trial:** - You are a Veteran between 18 and 64 years old (male or female) - You have chronic insomnia, meaning you have trouble falling asleep, staying asleep, or waking too early at least 3 nights per week for 3 or more months, and it affects your daytime functioning - Your insomnia i...

Phase 2: ~30% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT05456958 · Andrew Nicholson Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 September 2025
🇨🇦 CA

Who might be able to join this trial: - You are between 18 and 65 years old - You speak English fluently - You are comfortable using electronic devices such as a laptop, tablet, or smartphone - You have been diagnosed with PTSD as your primary condition, confirmed through a structured clinical interview - You are able...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05457985 · University of Michigan Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 August 2027
🇺🇸 US

**Who might be able to join this trial:** - People who receive care at a participating federally qualified health center (FQHC) - People who score 33 or higher on a standard PTSD symptom checklist called the PCL-5 - People who own a mobile device (such as a smartphone or tablet) that can run the PTSD Coach app - People...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05485701 · University of Oxford Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 August 2025
🇮🇳 IN

**Who might be able to join this trial:** *For Phases 1 and 2 of the study:* - Women aged 18 to 45 who are currently pregnant (at any stage of pregnancy) and are willing and able to give informed consent. - Women aged 18 to 45 who have given birth within the past 1 to 12 months and are willing and able to give inform...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05486793 · Boston University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 July 2027
🇺🇸 US

**Who might be able to join this trial:** - Pregnant women who are receiving prenatal care at the BMC Obstetrics and Gynecology (OB/GYN) Department - Women who started prenatal care before 28 weeks of pregnancy - Women who have symptoms of PTSD (post-traumatic stress disorder), either meeting the full diagnosis or havi...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05491538 · VA Office of Research and Development Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 27 November 2026
🇺🇸 US

**Who might be able to join this trial:** - People who are veterans receiving outpatient care and support services at the Minneapolis VA Health Care System. - People who are currently working with a mental health team at the Minneapolis VA Health Care System, are motivated to find work, and are looking for employment...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05497115 · Medical University of South Carolina Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 March 2027
🇺🇸 US

**Who might be able to join this trial:** - You are 16 years old or older - You speak English or Spanish - You have been admitted to George Washington University Hospital's trauma center - You scored positive on a screening tool called the Injured Trauma Survivors Screen, which suggests you may be at risk of developing...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05516277 · University of California, Los Angeles Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 March 2027
🇺🇸 US

**Who might be able to join this trial:** - You are a Veteran aged 50 or older who lives independently in the community - You have received care at a Veterans Health Administration (VHA) facility within the past year - You have been diagnosed with PTSD (post-traumatic stress disorder) - You have been diagnosed with ins...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05516862 · Paul Crawford Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 October 2026
🇺🇸 US

Who might be able to join this trial: - People who are Active Duty military members or Department of Defense beneficiaries (such as former military personnel, spouses, or dependent children), aged 18 to 65 years old - People who score 31 or higher on a standard PTSD screening questionnaire (the PCL-5), based on experie...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05517304 · VA Office of Research and Development Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 8 July 2027
🇺🇸 US

Who might be able to join this trial: - Veterans aged between 18 and 75 who have been diagnosed with PTSD (post-traumatic stress disorder) according to standard diagnostic guidelines (DSM-5) Who may not be able to join: - People with a history of mild traumatic brain injury (a type of head injury), based on Veterans A...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05527509 · University of Regina Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 December 2024
🇨🇦 CA

Who might be able to join this trial: - People who are starting the RCMP Cadet Training Program as a cadet Who may not be able to join: - Anyone who is not a cadet beginning the RCMP Cadet Training Program Important: Always verify eligibility with the trial site directly before applying.

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05534243 · Washington University School of Medicine Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 March 2027
🇺🇸 US

Who might be able to join this trial: - You are 18 years of age or older - You are breathing with the help of a machine (ventilator) through a tube placed in your throat - You have been given a medicine to temporarily relax or paralyze your muscles, either during the process of having the breathing tube put in or short...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05560113 · Emory University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 December 2028
🇺🇸 US

**Who might be able to join this trial:** - You are able to understand and sign a consent form agreeing to take part in the study - You are willing to participate in the study - You have no history of muscle, bone, or joint problems, or any neurological (brain or nerve) conditions - For participants in the PTSD group:...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05563805 · The University of Texas at Arlington Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 August 2027
🇺🇸 US

**Who might be able to join this trial:** - People who are between 18 and 45 years old - People who identify as a U.S. military veteran - People who have normal vision with no color blindness **Who may not be able to join:** - People who are unable to walk independently, or who use any kind of mobility aid such as a b...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05608551 · University of Basel Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 December 2025
🇨🇭 CH

**Who might be able to join this trial:** - Children and teenagers aged between 9 and 17 years - People who have experienced a traumatic event and can remember at least one of those events - People showing post-traumatic stress symptoms, as measured by a screening tool called the CATS-2 (a score of 21 or higher is requ...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05624931 · Boston University Charles River Campus Not Applicable · 2 countries Recruiting
Recruiting Not Applicable Est. completion 28 February 2027
🇿🇦 ZA🇺🇸 US

Who might be able to join this trial: - People who are female and aged 15 or older - People who are currently pregnant and receiving antenatal (pregnancy) care at the Gugulethu Midwife Obstetric Unit (MOU) - People who are HIV-negative - People who either started taking PrEP (a medication that helps prevent HIV) less t...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05637879 · White River Junction Veterans Affairs Medical Center Phase 3 · 1 country Recruiting
Recruiting Phase 3 Est. completion 31 December 2025
🇺🇸 US

**Who might be able to join this trial:** - People between 19 and 70 years of age - People who weigh at least 45 kg (approximately 99 lbs) - People who have been diagnosed with PTSD using a specific clinical assessment (called the CAPS-5), completed within seven days of enrolling in the trial - People who are eligible...

Phase 3: ~65% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT05646732 · Allyson Rosen Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 January 2025
🇺🇸 US

**Who might be able to join this trial:** - People aged between 18 and 55 years old - People who are able to have a specific type of brain stimulation test called single pulse TMS performed safely and with a measurable response - People who are able to safely and comfortably undergo both an MRI scan and TMS (a type of...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05662423 · Massachusetts General Hospital Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 20 July 2026
🇺🇸 US

Who might be able to join this trial: - Women who have recently given birth at Massachusetts General Hospital (MGH). - Women who score higher than 16 on a screening tool called the Peritraumatic Distress Inventory (PDI), which suggests they may be at risk of developing trauma-related stress connected to childbirth. Wh...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05663151 · VA Boston Healthcare System Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 January 2027
🇺🇸 US

**Who might be able to join this trial:** - You have been diagnosed with PTSD, confirmed through a structured clinical interview using current diagnostic guidelines - You are interested in taking part in a type of therapy called Prolonged Exposure (PE) - You are a Veteran **Who may not be able to join:** - You have be...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05674617 · VA Office of Research and Development Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 March 2027
🇺🇸 US

**Who might be able to join this trial:** - You are currently receiving outpatient mental health care through the VA Maryland Health Care System (this includes general mental health clinics, recovery centers, intensive case management programs, or PTSD treatment teams) - You have been diagnosed with PTSD, confirmed thr...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05683132 · VA Office of Research and Development Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 December 2027
🇺🇸 US

**Who might be able to join this trial:** - Women Veterans who live in the community (not in a care facility) and are 18 years of age or older - People who have received care from the VA Greater Los Angeles Healthcare System (VAGLAHS) - People who are currently experiencing symptoms of PTSD (post-traumatic stress disor...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05700279 · Rush University Medical Center Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 February 2027
🇺🇸 US

**Who might be able to join this trial:** - People aged 18 to 70 years old - People who can read and write English well enough to complete questionnaires and take part in interviews - People who have come to the Rush Emergency Department with sudden, acute pain that is not caused by a serious physical injury - People...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05701111 · Stanford University Not Applicable · 2 countries Recruiting
Recruiting Not Applicable Est. completion 1 May 2027
Puerto Rico🇺🇸 US

Who might be able to join this trial: - Teachers, students, adults, and caregivers at a participating school who are willing to take part in the study - Young people aged 11 to 17 who have experienced at least one traumatic event and are showing significant trauma-related symptoms (as measured by a standard UCLA questi...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05732116 · Xijing Hospital Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 November 2025
🇨🇳 CN

Who might be able to join this trial: - Surgeons and anesthesiologists who are registered at the study center Who may not be able to join: - Surgeons and anesthesiologists who may be moving to a different practice location during the study period - Surgeons and anesthesiologists who are not willing to sign a consent f...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05732155 · HaEmek Medical Center, Israel Phase 2 · 1 country Recruiting
Recruiting Phase 2 Est. completion 1 June 2027
🇮🇱 IL

**Who might be able to join this trial:** - People who served as veterans of special forces undercover units in the Israeli army. - People who are fluent in speaking and reading Hebrew. - People who are able to swallow pills. - People who agree to have their study visits recorded, including therapy sessions and experi...

Phase 2: ~30% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT05734547 · Norwegian Center for Violence and Traumatic Stress Studies Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 December 2026
🇳🇴 NO

**Who might be able to join this trial:** - The child is between 7 and 12 years old - The child has experienced an event that is considered potentially traumatic under recognised diagnostic guidelines (DSM-5) - The child has at least 5 post-traumatic stress symptoms, and at least one of those symptoms involves re-expe...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05737693 · Yale University Phase 2 · 2 countries Recruiting
Recruiting Phase 2 Est. completion 1 August 2030
🇮🇱 IL🇺🇸 US

**Who might be able to join this trial:** - You are between 21 and 70 years old (male or female). - If you are a woman who could become pregnant, you agree to use an accepted form of birth control, or you are post-menopausal for at least 1 year, or have had a surgical procedure that prevents pregnancy. - You do not ha...

Phase 2: ~30% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT05751473 · University of Michigan Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 June 2027
🇺🇸 US

**Who might be able to join this trial:** - People who work at an organisation that is served by a participating Employee Assistance Program (EAP) - People who score 33 or higher on a standardised checklist used to assess PTSD symptoms (called the PCL-5) - People whose psychiatric medications (if any) have remained unc...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05758987 · Karolinska Institutet Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 10 October 2026
🇸🇪 SE

Who might be able to join this trial: - You have been diagnosed with PTSD (Post-Traumatic Stress Disorder) as your main mental health concern - You are 18 years old or older - You have a basic ability to speak and read Swedish - You are not currently receiving any other psychological therapy or counselling - You are no...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05780177 · VA Office of Research and Development Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 April 2027
🇺🇸 US

**Who might be able to join this trial:** - You are a veteran between the ages of 18 and 75 - You have been diagnosed with Insomnia Disorder based on standard medical guidelines (DSM-5) - You have been diagnosed with PTSD based on standard medical guidelines (DSM-5) - If you are taking any medications for sleep, PTSD,...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05786157 · Medical University of South Carolina Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 October 2028
🇺🇸 US

**Who might be able to join this trial:** - People of any gender identity, race, or ethnicity who are 21 years of age or older - People who report having 2 or more heavy drinking episodes in the past 30 days (defined as 4 or more drinks within 2 hours for women, or 5 or more drinks within 2 hours for men), and who hav...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05788302 · Massachusetts General Hospital Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 March 2027
🇺🇸 US

**Who might be able to join this trial:** - People aged 18 or older - People who have been diagnosed with PTSD according to standard diagnostic criteria (DSM-5), confirmed through a structured diagnostic interview - People who are interested in starting a therapy called Prolonged Exposure (PE) **Who may not be able to...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05812131 · VA Office of Research and Development Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 January 2027
🇺🇸 US

Who might be able to join this trial: - People who currently work as a provider in a behavioral health field, such as psychology, psychiatry, or counseling - People who are at least 18 years old - People who speak English - People who have consistent access to a reliable internet connection - People who are willing to...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05837845 · Patricia Suppes Phase 2 · 1 country Recruiting
Recruiting Phase 2 Est. completion 1 May 2027
🇺🇸 US

**Who might be able to join this trial:** - People who are at least 18 years old at the time of signing the consent form - People who are U.S. Military Veterans - People who are currently receiving services from VA Palo Alto Healthcare System, VA San Francisco Healthcare System, or VA NorCal Healthcare System - People...

Phase 2: ~30% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT05843695 · Baylor College of Medicine Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 March 2027
🇺🇸 US

Who might be able to join this trial: - People who are a current or former member of the military and are at least 18 years old - People who have been diagnosed with at least one anxiety-related condition, such as Post-Traumatic Stress Disorder (PTSD), Panic Disorder, Social Anxiety Disorder, or Generalized Anxiety Dis...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05853627 · Massachusetts General Hospital Phase 4 · 1 country Recruiting
Recruiting Phase 4 Est. completion 1 July 2026
🇺🇸 US

**Who might be able to join this trial:** - People aged 18 to 65 who have been through a traumatic event that meets a specific clinical definition of trauma (known as DSM-5 PTSD Criterion A) - People who score above 33 on a standard PTSD symptom checklist called the PCL-5 - People who show a specific physical (psychop...

Phase 4 trials study a drug that has already been approved, monitoring long-term safety and effectiveness in real-world use.
NCT05874362 · Hôpital le Vinatier Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 19 September 2026
🇫🇷 FR

Who might be able to join this trial: - You are between 18 and 65 years old - You have recently lost a close family member (such as a parent, sibling, child, grandparent, aunt, uncle, niece, or nephew) due to a violent death Who may not be able to join: - You are a legally protected adult (for example, someone under c...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05889741 · The University of Texas Health Science Center at San Antonio Phase 2 · 1 country Recruiting
Recruiting Phase 2 Est. completion 31 March 2027
🇺🇸 US

**Who might be able to join this trial:** - People who are active duty or retired military service members between 18 and 65 years old - People who have been diagnosed with PTSD, confirmed through a structured clinical assessment called the Clinician-Administered PTSD Scale - People who are able to speak and read Engli...

Phase 2: ~30% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT05893485 · Christina Chianis Reed Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 March 2026
🇺🇸 US

Who might be able to join this trial: - You are a pregnant woman between 18 and 64 years old - You are pregnant with one baby (not twins, triplets, etc.) - You have been admitted to hospital because of a high risk of going into early labour - Your waters have broken early (before your due date) - You have already been...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05895006 · The University of Texas Health Science Center, Houston Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 December 2026
🇺🇸 US

Who might be able to join this trial: - People who are right-handed - People who have normal vision or vision that is fully corrected with glasses or contact lenses, and a normal sense of smell - People between the ages of 18 and 50 years - People who pass a safety screening checklist for the brain stimulation method u...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05915013 · Yale University Phase 1 · 1 country Recruiting
Recruiting Phase 1 Est. completion 1 December 2032
🇺🇸 US

Who might be able to join this trial: - People who are right-handed, as measured by a standard handedness questionnaire - People who are currently experiencing depression, shown by a score above 17 on a standard depression rating scale - People whose depression has not improved after trying at least one antidepressant...

Phase 1: ~10% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT05916417 · Florida State University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 June 2026
🇺🇸 US

**Who might be able to join this trial:** - You are between 18 and 70 years old - Your doctor has considered you a possible candidate for TMS (a type of brain stimulation treatment) for PTSD - You have been diagnosed with PTSD based on a specific clinical assessment called the CAPS-5 - If you take any mental health med...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05929911 · Montefiore Medical Center Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 June 2027
🇺🇸 US

Who might be able to join this trial: - People who have been diagnosed with PTSD (post-traumatic stress disorder) according to a standardised clinical assessment, with a symptom severity score of 25 or above on that assessment - People who have been diagnosed with HIV, confirmed through medical records or HIV testing -...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05934162 · Karolinska Institutet Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 20 August 2025
🇸🇪 SE

Who might be able to join this trial: - People who have a current primary diagnosis of PTSD (post-traumatic stress disorder) based on standard diagnostic guidelines (DSM-5) - People who are 18 years of age or older - People who can read and communicate fluently in Swedish - People who have been on a stable dose of any...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05934175 · Karolinska Institutet Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 20 June 2027
🇸🇪 SE

Who might be able to join this trial: - People who are 18 years of age or older - People who have a primary diagnosis of PTSD (Post-Traumatic Stress Disorder) - People who are fluent in Swedish - People who are willing and able to sign a consent form agreeing to take part in the trial - People who are able to attend ei...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05943665 · Carolina L Haass-Koffler Phase 2 · 1 country Recruiting
Recruiting Phase 2 Est. completion 21 January 2026
🇺🇸 US

**Who might be able to join this trial:** - People who are able to provide proof of their veteran status. - People who speak and read English fluently. - People who, at the start of the study, meet the clinical criteria for Alcohol Use Disorder, as measured by a structured diagnostic interview called the SCID-5. - Peo...

Phase 2: ~30% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT05959434 · Texas A&M University Phase 2 · 1 country Recruiting
Recruiting Phase 2 Est. completion 30 June 2027
🇺🇸 US

**Who might be able to join this trial:** - People of any gender identity, race, or ethnicity who are 18 years of age or older - People who are able to sign a written consent form agreeing to take part - People who are able to understand English - People who have been diagnosed with moderate to severe alcohol use diso...

Phase 2: ~30% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT05974631 · VA Office of Research and Development Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 April 2027
🇺🇸 US

Who might be able to join this trial: - You have been diagnosed with PTSD (Post-Traumatic Stress Disorder) - You have recently and repeatedly harmed yourself on purpose - You are currently having thoughts of suicide - You have difficulty managing your emotions - You are a Veteran who is eligible to receive mental healt...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT05989841 · University of Nevada, Las Vegas Phase 2 · 1 country Recruiting
Recruiting Phase 2 Est. completion 28 February 2027
🇺🇸 US

**Who might be able to join this trial:** - You are a woman who has survived a sexual assault and came to an emergency care location within 72 hours of the assault - You are 18 years of age or older - You speak and understand English - You are able to agree to take part in the study on your own (give informed consent)...

Phase 2: ~30% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT05995678 · VA Office of Research and Development Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 May 2027
🇺🇸 US

**Who might be able to join this trial:** - You left military service within the last three years - You have reported some difficulty with daily functioning or adjusting to civilian life, based on a specific questionnaire about military-to-civilian transition (any area where you said you have "some difficulty" or more)...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06000475 · VA Office of Research and Development Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 June 2026
🇺🇸 US

Who might be able to join this trial: - People who are military veterans and have been diagnosed with PTSD according to the DSM-5 standard, confirmed through a specific clinical interview called the CAPS-5 - People who are over 59 years of age Who may not be able to join: - People who use benzodiazepine medications (a...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06002633 · University of Texas at Austin Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 May 2028
🇺🇸 US

**Who might be able to join this trial:** - You are between 21 and 60 years old - In the past year, you have had at least 4 drinks (if male) or at least 3 drinks (if female) on at least two separate occasions - If joining as a PTSD participant: you have been diagnosed with PTSD, confirmed through a structured interview...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06035809 · London Health Sciences Centre Research Institute OR Lawson Research In... Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 15 April 2028
🇨🇦 CA

Who might be able to join this trial: - Adults between 18 and 65 years old - People who have received a primary diagnosis of PTSD, confirmed through the trial's own pre-treatment assessment - People who are able to give informed consent to participate - People who can read, write, and speak English well enough to compl...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06037785 · University of Washington Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 July 2026
🇺🇸 US

Who might be able to join this trial: - People who have had an ICD (a small device implanted in the chest to help control dangerous heart rhythms) fitted to reduce the risk of sudden cardiac arrest - People who have received at least one shock from their ICD in the week before joining the study, whether the shock was t...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06044675 · Remedy Phase 2 · 1 country Recruiting
Recruiting Phase 2 Est. completion 31 December 2026
🇨🇦 CA

Who might be able to join this trial: **For the person with PTSD:** - People who have a diagnosis of PTSD that meets the study's criteria. - People who have a close person in their life (such as a partner, family member, or friend) who is willing and able to take part in the study alongside them. - People who are at l...

Phase 2: ~30% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT06047691 · Penn State University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 February 2026
🇺🇸 US

**Who might be able to join this trial:** - One person in the couple must be a current military service member or veteran, and their romantic partner must also be willing to take part. - The couple must be married or living together for at least 3 months (both different-sex and same-sex couples are welcome). - The serv...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06070766 · RIVER Foundation Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 October 2028
🇺🇸 US

Who might be able to join this trial: - You have a long-term (ongoing) health condition that has been identified by a doctor. Who may not be able to join: - You are generally healthy and do not have any ongoing health conditions. Important: Always verify eligibility with the trial site directly before applying.

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06073886 · University of California, Los Angeles Phase 2 · 1 country Recruiting
Recruiting Phase 2 Est. completion 1 July 2026
🇺🇸 US

**Who might be able to join this trial:** - You have had a mild traumatic brain injury (concussion) within the last 12 months, diagnosed using World Health Organization guidelines - You were between 18 and 65 years old at the time of your concussion - You are currently experiencing a high level of post-concussion sympt...

Phase 2: ~30% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT06088303 · Boston University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 October 2028
🇺🇸 US

Who might be able to join this trial: - People who have been diagnosed with PTSD (Post-Traumatic Stress Disorder) - People who have been taking the same psychiatric medications at a stable dose for at least 4 weeks Who may not be able to join: - People whose bipolar disorder is currently unstable or not well-managed -...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06093906 · Case Western Reserve University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 June 2026
🇺🇸 US

Who might be able to join this trial: - People who experienced a major life event involving serious loss or threat, where the event happened at least 12 weeks ago but within the last 5 years. - People who are between 18 and 65 years of age. - People who score at a moderate level or higher on at least 2 of 3 specific ar...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06094933 · VA Office of Research and Development Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 October 2027
🇺🇸 US

**Who might be able to join this trial:** - People who are veterans and have been diagnosed with PTSD, confirmed through their medical records and a score of 33 or higher on a standard PTSD symptom questionnaire called the PCL-5 - People who score 12 or higher on a 5-item questionnaire that measures anger reactions - P...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06096740 · University of Texas at Austin Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 March 2029
🇺🇸 US

**Who might be able to join this trial:** - English is your main language, and you can understand instructions given by the research team. - You have been diagnosed with PTSD (caused by a traumatic event you experienced), and your symptoms have been present for at least 3 months, confirmed through a professional asses...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06111976 · Assistance Publique - Hôpitaux de Paris Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 7 July 2026
🇫🇷 FR

**Who might be able to join this trial:** - People aged between 18 and 65 years - People who have been diagnosed with PTSD (Post-Traumatic Stress Disorder) according to standard medical diagnostic guidelines (DSM-5) - People whose PTSD symptoms remain significant (as measured by a score above 40 on a standard PTSD sym...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06117306 · Healing Breakthrough Phase 3 · 1 country Recruiting
Recruiting Phase 3 Est. completion 31 August 2027
🇺🇸 US

**Who might be able to join this trial:** - Veterans aged 18 to 64 who have been assessed and meet the criteria for PTSD with a severity score of 25 or higher on a standard clinical assessment tool called the CAPS-5. - People who speak and read English fluently. - People who are willing to attend all medication sessio...

Phase 3: ~65% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT06127342 · Christal L Badour Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 September 2026
🇺🇸 US

Who might be able to join this trial: - Adults who have been diagnosed with PTSD (post-traumatic stress disorder) that developed as a result of interpersonal violence (such as abuse, assault, or similar experiences) Who may not be able to join: - People who currently have, or have had in the last 3 months, a severe pr...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06138522 · Assistance Publique - Hôpitaux de Paris Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 May 2028
🇫🇷 FR

**Who might be able to join this trial:** **For teenagers:** - You are between 12 and 18 years old - You have been diagnosed with Post-Traumatic Stress Disorder (PTSD), based on standard diagnostic guidelines - You are already being seen at the Maison de Solenn (a centre for adolescents) - You are covered by a social...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06144203 · University of Alabama, Tuscaloosa Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 March 2029
🇺🇸 US

**Who might be able to join this trial:** **For people with PTSD:** - You can be male or female - You are right-handed - You are between 18 and 64 years old - You have a current diagnosis of PTSD that resulted from a experience involving interpersonal violence (such as physical or sexual assault) **For people who hav...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06150196 · East Bay Institute for Research and Education Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 May 2026
🇺🇸 US

Who might be able to join this trial: - You are between 18 and 75 years old - You have had one or more mild traumatic brain injuries (such as concussions) lasting more than 6 months ago, and this has been an ongoing issue - You have been diagnosed with PTSD (Post-Traumatic Stress Disorder) - You are currently experienc...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06162741 · VA Office of Research and Development Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 July 2027
🇺🇸 US

**Who might be able to join this trial:** - People who are enrolled in primary care at the local VA (Veterans Affairs) health site - People who are experiencing significant emotional or mental distress in at least one of the following areas: post-traumatic stress (scoring 30 or above on a standard PTSD checklist, plus...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06185244 · Karolinska Institutet Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 4 January 2027
🇸🇪 SE

Who might be able to join this trial: - People aged 13 to 17 years old - People who have been given a primary diagnosis of PTSD (post-traumatic stress disorder) - People who are fluent in Swedish - People who have internet access at home, or for whom internet vouchers for phone access can be provided - People whose par...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06193161 · Karolinska Institutet Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 15 October 2025
🇸🇪 SE

Who might be able to join this trial: - People who have a current main (primary) diagnosis of PTSD, confirmed using the standard DSM-5 diagnostic guidelines - People who are 18 years of age or older - People who are able to read and write in English - People who are immigrants currently living in Sweden - People who ar...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06194851 · VA Office of Research and Development Phase 2 · 1 country Recruiting
Recruiting Phase 2 Est. completion 30 September 2028
🇺🇸 US

Who might be able to join this trial: **For the Veteran:** - Veterans aged 18 or older who have been diagnosed with PTSD (using a standard clinical assessment) with symptoms of at least moderate severity, and where at least 3 months have passed since the traumatic event - Veterans whose psychiatric medications (if any...

Phase 2: ~30% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT06210711 · Baylor Research Institute Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 March 2027
🇺🇸 US

Who might be able to join this trial: - You are between 18 and 75 years old - You have been admitted to one of these hospitals: Baylor University Medical Center in Dallas, Baylor Scott & White Medical Center in Temple, or Froedtert Hospital and the Medical College of Wisconsin Level 1 Trauma Center Who may not be able...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06218381 · Children's Hospital Los Angeles Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 July 2026
🇺🇸 US

Who might be able to join this trial: **For people with PTSD:** - You are a man or woman between the ages of 18 and 50 - You have been officially diagnosed with PTSD according to standard diagnostic guidelines (DSM-5) - Your PTSD is connected to a combat-based experience, such as being injured in combat or witnessing...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06219408 · University of Washington Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 May 2027
🇺🇸 US

**Who might be able to join this trial:** *For clinic staff:* - People aged 18 or older who work at or are in training at the clinic *For patients:* - People aged 18 or older - People who speak English - People who are already a patient at the clinic where recruitment is taking place - People who experience pain on m...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06234969 · University of Pennsylvania Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 July 2028
🇺🇸 US

Who might be able to join this trial: - You are between 18 and 60 years old - You have been diagnosed with PTSD, confirmed through a structured clinical interview using standard diagnostic guidelines - You do not have any metal implants in your body Who may not be able to join: - You are currently pregnant - You have...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06261463 · University of Illinois at Chicago Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 August 2026
🇺🇸 US

Who might be able to join this trial: - The family's country of origin is Iraq, Syria, Lebanon, Jordan, Palestine, or Yemen - The family is living in Chicago as a refugee family and has been there for less than three years - The household includes at least one adult caregiver between the ages of 18 and 55, and at least...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06262178 · New York University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 May 2027
🇺🇸 US

**Who might be able to join this trial:** - You are a mother who is a female service member, veteran, or the female spouse/partner of a service member or veteran - You have a child between the ages of 2 and 10 - You are the legal guardian of that child and have both legal and physical custody - You have experienced at...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06266364 · The University of Texas at Dallas Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 September 2027
🇺🇸 US

**Who might be able to join this trial:** - You have been diagnosed with chronic PTSD (post-traumatic stress disorder) for at least 3 months, based on standard medical criteria - In the lead doctor's opinion, at least one standard, recommended PTSD treatment has not worked well enough for you - Your score on a standard...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06278922 · University of Massachusetts, Worcester Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 November 2028
🇺🇸 US

**Who might be able to join this trial:** - People who identify as Deaf or hard-of-hearing - People who are proficient in American Sign Language (ASL) - People who are 18 years of age or older - People who have access to video calling technology (such as a computer or tablet with a camera), which would be needed for co...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06279598 · University of Groningen Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 20 May 2031
🇳🇱 NL

**Who might be able to join this trial:** - Adults aged between 18 and 65 who have been given a primary diagnosis of PTSD, based on standard diagnostic criteria (DSM-5). - Adults who are willing to take part and have given their formal agreement to participate in the study. **Who may not be able to join:** - People wh...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06285708 · Ohio State University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 December 2026
🇺🇸 US

Who might be able to join this trial: - People who have a current diagnosis of PTSD or a milder form of PTSD that does not fully meet the standard diagnostic criteria - People who can speak and understand English - People who are able to go through the informed consent process Who may not be able to join: - People who...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06288711 · University of Vermont Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 August 2027
🇺🇸 US

Who might be able to join this trial: - People who are over 18 years old - People who have been on a stable dose of methadone or buprenorphine for more than one month before the study begins - People who have been diagnosed with post-traumatic stress disorder (PTSD) according to a structured clinical assessment - Peopl...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06289621 · Massachusetts General Hospital Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 July 2026
🇿🇦 ZA

Who might be able to join this trial: - You have been diagnosed with a primary anxiety disorder, which includes panic disorder, generalized anxiety disorder, social anxiety disorder, or obsessive-compulsive disorder (OCD), or post-traumatic stress disorder (PTSD). Who may not be able to join: - You are currently havin...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06294106 · Virginia Polytechnic Institute and State University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 June 2028
🇺🇸 US

Who might be able to join this trial: - You are a veteran or a first responder (such as a police officer, firefighter, or paramedic) - You have been diagnosed with post-traumatic stress disorder (PTSD) and scored 31 or higher on a standard PTSD symptom checklist called the PCL-5 Who may not be able to join: - You have...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06296186 · Veterans Medical Research Foundation Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 July 2027
🇺🇸 US

Who might be able to join this trial: - People who are veterans aged 18 or older - People who have served in the military since September 2001 - People who are currently enrolled in an intensive outpatient program for substance use disorder at a participating VA facility - People who have been diagnosed with a substanc...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06296589 · Veterans Medical Research Foundation Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 July 2027
🇺🇸 US

Who might be able to join this trial: - You are a U.S. Veteran aged 18 or older who served in the military from the start of Operation Enduring Freedom or Operation Iraqi Freedom (OEF/OIF) onward - You have been diagnosed with PTSD (Post-Traumatic Stress Disorder) - You experience significant trauma-related guilt, show...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06298279 · University of Regina Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 April 2027
🇨🇦 CA

Who might be able to join this trial: - People who are 18 years of age or older - People who currently work, have previously worked, or are training as public safety personnel (such as police, firefighters, paramedics, or similar roles) - People who are living in Canada at the time of joining the study - People who hav...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06300255 · VA Salt Lake City Health Care System Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 February 2029
🇺🇸 US

Who might be able to join this trial: - You must be a veteran who has served in the military - You must be enrolled in a H.O.O.V.E.S. Healing Intensives Program - You must be able to speak and understand English Who may not be able to join: - There are no specific exclusion criteria listed for this trial (confirm with...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06310109 · Bambino Gesù Children's Hospital IRCCS Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 October 2024
🇮🇹 IT

Who might be able to join this trial: - Children or teenagers who have been admitted to a Pediatric Intensive Care Unit (PICU) - Children or teenagers who have been on a breathing machine (mechanical ventilator) for more than 48 hours - Children or teenagers under 19 years of age Who may not be able to join: - Childre...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06330779 · University West, Sweden Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 December 2027
🇸🇪 SE

Who might be able to join this trial: - Teenagers who have already been officially diagnosed (not still being assessed) with PTSD and/or ADHD - People who can understand and communicate in English or Swedish Who may not be able to join: - People who are currently using drugs or alcohol in a problematic way - People wh...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06332209 · Medical University of South Carolina Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 September 2026
🇺🇸 US

Who might be able to join this trial: - Children and teenagers between 7 and 18 years old - People who have experienced at least one traumatic event - People who are showing a significant level of post-traumatic stress symptoms Who may not be able to join: - People who are currently having serious thoughts of suicide...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06333990 · Foundation for Advancing Veterans' Health Research Phase 3 · 1 country Recruiting
Recruiting Phase 3 Est. completion 1 June 2028
🇺🇸 US

**Who might be able to join this trial:** - Veterans (male or female) who are seeking treatment for mild traumatic brain injury (mild TBI) and are between 18 and 65 years old - People who have been diagnosed with mild TBI and are experiencing ongoing symptoms after the injury, with at least 6 months having passed sinc...

Phase 3: ~65% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT06335407 · Pharmacotherapies for Alcohol and Substance Use Disorders Alliance Phase 1 · 1 country Recruiting
Recruiting Phase 1 Est. completion 30 March 2026
🇺🇸 US

**Who might be able to join this trial:** - People who are between 21 and 65 years old, including both veterans and non-veterans - People who can read and write in English and are able to sign a consent form - People who are willing to follow all study procedures and attend all required appointments for the full lengt...

Phase 1: ~10% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT06341413 · University of Wisconsin, Madison Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 October 2028
🇺🇸 US

**Who might be able to join this trial:** - You are between 15 and 18 years old (inclusive) - You are able to lie still on your back for up to 1 hour - You are not pregnant and do not become pregnant during the study - You agree to tell the research team about any urgent medical situations within 48 hours of them happ...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06348472 · Shalvata Mental Health Center Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 March 2028
🇮🇱 IL

Who might be able to join this trial: - People who score at least 33 on a standard PTSD symptom questionnaire called the PCL-5. - People whose treatment plan includes between 12 and 24 psychotherapy sessions. Who may not be able to join: - People who have experienced a psychotic episode. - Women who are pregnant or br...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06363968 · VA Puget Sound Health Care System Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 September 2025
🇺🇸 US

**Who might be able to join this trial:** - You are a veteran of the U.S. Armed Forces - You have been diagnosed with PTSD (Post-Traumatic Stress Disorder) **Who may not be able to join:** - You have been diagnosed with a primary psychotic disorder or a major disorder affecting memory and thinking - You have significa...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06366282 · Wake Forest University Health Sciences Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 July 2026
🇺🇸 US

Who might be able to join this trial: - The child must be admitted to hospital for treatment of an accidental injury, such as burns, a dog bite, or a road traffic accident, in a paediatric trauma or burns unit - The adult caregiver must speak English as their primary language, as recorded in the hospital's electronic r...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06367764 · Stanford University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 June 2028
🇺🇸 US

**Who might be able to join this trial:** - You are 18 years of age or older - You currently live in California - You are able to understand what the study involves and follow through with it for the whole duration - You are able to read and understand a consent form and are willing to sign it - You are able to speak a...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06371404 · Yale University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 June 2030
🇺🇸 US

**Who might be able to join this trial:** - You are willing and able to sign a written consent form agreeing to take part - You can read, write, and communicate clearly with the research team, and are able to follow all study instructions - You are a man or woman between 18 and 70 years old - You are in generally good...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06386003 · Unity Health Toronto Phase 2 · 1 country Recruiting
Recruiting Phase 2 Est. completion 1 January 2027
🇨🇦 CA

Who might be able to join this trial: - People who have been diagnosed with PTSD (according to standard psychiatric guidelines) for at least 6 months, as confirmed by a study psychiatrist - People whose PTSD symptoms are rated as moderate to severe based on a standardised assessment score of 50 or higher - People who a...

Phase 2: ~30% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT06394284 · Herzog Hospital Phase 3 · 1 country Recruiting
Recruiting Phase 3 Est. completion 31 December 2027
🇮🇱 IL

**Who might be able to join this trial:** - People who were assigned male sex at birth and currently identify as male (not transgender and not taking hormone therapy) - People who have served in the Israeli military - People who are at least 18 years old - People who can speak and read Hebrew fluently - People who are...

Phase 3: ~65% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT06399874 · Uniformed Services University of the Health Sciences Phase 2 · 1 country Recruiting
Recruiting Phase 2 Est. completion 1 October 2025
🇺🇸 US

**Who might be able to join this trial:** - People who are currently serving in the military or who have previously served (veterans) - People who have been experiencing at least one nightmare per week over the past month - People who score at least 8 on a standard sleep difficulty questionnaire called the ISI (Insomni...

Phase 2: ~30% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT06414356 · Margaux M. Salas, PhD Phase 4 · 1 country Recruiting
Recruiting Phase 4 Est. completion 1 April 2025
🇺🇸 US

Who might be able to join this trial: - People aged 18 to 70 years old who have had chronic nerve pain lasting 3 months or longer - Both biological males and biological females are eligible - Women of childbearing age may be eligible if they have no plans to become pregnant during the study period, agree to use contrac...

Phase 4 trials study a drug that has already been approved, monitoring long-term safety and effectiveness in real-world use.
NCT06418178 · Bronx VA Medical Center Phase 2 · 1 country Recruiting
Recruiting Phase 2 Est. completion 1 October 2029
🇺🇸 US

**Who might be able to join this trial:** - People who are U.S. military veterans aged 18 or older. - People who are able to give written informed consent. - People who are able to swallow pills. - People who agree to have study visits recorded, including therapy sessions and assessments. - People who can provide a con...

Phase 2: ~30% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT06419959 · VA Office of Research and Development Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 September 2026
🇺🇸 US

**Who might be able to join this trial:** - People who have been diagnosed with PTSD according to the DSM-5 (the standard diagnostic guidelines used by mental health professionals) - People who report having repeated nightmares that disturb their sleep - People who are 22 years of age or older - People whose resting b...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06429293 · Massachusetts General Hospital Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 July 2026
🇺🇸 US

Who might be able to join this trial: - People between 18 and 65 years old - People who have experienced a traumatic event and have significant PTSD symptoms across at least two symptom groups - People who have been diagnosed with heart or artery disease (such as a heart attack, blocked arteries, or calcium buildup in...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06434766 · Second Affiliated Hospital, School of Medicine, Zhejiang University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 December 2026
🇨🇳 CN

**Who might be able to join this trial:** - People aged between 18 and 65 years old - People who are right-handed - People who have been diagnosed with PTSD according to the DSM-5 diagnostic guidelines - People whose PTSD symptom score (measured by a tool called the CAPS-5) is above 35, indicating significant symptoms...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06442423 · Yale University Phase 1 · 1 country Recruiting
Recruiting Phase 1 Est. completion 1 December 2027
🇺🇸 US

Who might be able to join this trial: - People who have experienced at least one mental health symptom in the past 30 days that has affected their ability to function in daily life, based on standardised assessments used by trained staff. - People who are fluent in English and able to understand what the study involves...

Phase 1: ~10% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT06449326 · University of New Mexico Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 October 2027
🇺🇸 US

**Who might be able to join this trial:** - You are a Veteran between the ages of 18 and 80 - You have a confirmed PTSD diagnosis and are currently experiencing symptoms, shown by a score of 31 or higher on a standard PTSD symptom questionnaire called the PCL-5 - You are fluent in English, as the testing tools used in...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06464952 · Hunter Holmes Mcguire Veteran Affairs Medical Center Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 25 June 2027
🇺🇸 US

Who might be able to join this trial: - People who are older than 18 years of age - People who are able to read and sign a consent form agreeing to take part - People who have been diagnosed with cirrhosis (scarring of the liver) - People who are willing to follow all study procedures and remain available for the full...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06467916 · University of Colorado, Denver Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 April 2026
🇺🇸 US

Who might be able to join this trial: **For parents:** - Parents of a premature baby who is currently staying in the NICU (newborn intensive care unit) at one of two participating hospitals (OHSU or UCH) - The premature baby must have been in the NICU for at least 2 weeks at the time of joining - The baby must current...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06477796 · VA Office of Research and Development Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 December 2027
🇺🇸 US

Who might be able to join this trial: - You must be a Veteran. - You must speak English and have access to a phone and the internet. - You must currently have trouble sleeping, based on what you report yourself. - Your current treatments for depression, anxiety, sleep problems, or pain (whether medication or therapy) m...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06479447 · University of Chicago Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 14 July 2026
🇺🇸 US

Who might be able to join this trial: - You are 18 years old or older - You have had at least one appointment at the study location within the last 24 months - You have not been screened or tested for PTSD (Post-Traumatic Stress Disorder) in the last 12 months Who may not be able to join: - There are no listed reasons...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06482567 · University of North Carolina, Chapel Hill Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 March 2027
🇺🇸 US

**Who might be able to join this trial:** - People aged 18 to 50 years old (if age is not known, those who appear to be in this age range) - People who are in the emergency department, either as a patient or as a family member or loved one of a patient - Patients who are expected to be sent home after being seen in the...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06494319 · The University of Texas Health Science Center, Houston Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 June 2025
🇺🇸 US

**Who might be able to join this trial:** - People who are current or former members of the US Military (Veterans or active Service Members) - People who have been assessed with PTSD, shown by a score above 33 on a standard PTSD checklist (PCL-5) - People who have experienced combat trauma or served in a location that...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06516874 · University of Talca Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 28 February 2027
🇨🇱 CL

**Who might be able to join this trial:** - Adults aged 18 or older, of any gender. - People who have been referred to a community mental health service or hospital in the Maule Region because of difficulties related to traumatic experiences, or who have symptoms or a diagnosis of Post-Traumatic Stress Disorder (PTSD)...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06521398 · University of Pennsylvania Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 August 2027
🇺🇸 US

Who might be able to join this trial: - Patients who gave birth at HUP (Hospital of the University of Pennsylvania) and are at least 16 years old at the time of their baby's birth - The baby must have been born at HUP - The baby must have been born prematurely, before 34 weeks of pregnancy - The patient must speak Engl...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06522022 · Emory University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 March 2029
🇺🇸 US

Who might be able to join this trial: - People who are 18 years of age or older - People who are able to give informed consent to participate - People who speak English - People who are willing to take part in the study - People who identify as Black or African American - People who are pregnant and in their first trim...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06526247 · Boston University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 July 2027
🇺🇸 US

Who might be able to join this trial: **For men:** - People who identify as a man - People who have been sent by a court to attend an intimate partner violence (IPV) intervention program in Washington state - People who agree to allow the research team to contact their intimate partner(s) to collect information for th...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06535243 · Centre Hospitalier St Anne Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 April 2027
🇫🇷 FR

Who might be able to join this trial: - People who have been diagnosed with complex PTSD (a trauma-related condition) - People who speak French - People who have not previously received this specific type of therapy, called LI therapy - People who are currently taking psychiatric medications may still be eligible Who...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06535516 · University of Rochester Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 August 2027
🇺🇸 US

**Who might be able to join this trial:** - Young people aged 10 to 15 years old at the time of joining the trial who are already seeking help at the University of Rochester Medical Center Pediatric Behavioral Health and Wellness clinic. - A parent or caregiver must agree to take part, and the young person must also ag...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06538246 · Duke University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 15 November 2027
🇺🇸 US

**Who might be able to join this trial:** - People who are 18 years of age or older - People who have been cared for in an intensive care unit (ICU) or a step-down unit for at least 24 hours - People who have had a serious, sudden heart or breathing problem during that hospital stay — this could include being on a bre...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06544408 · Florida State University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 June 2028
🇺🇸 US

Who might be able to join this trial: - Adults between 18 and 65 years of age. - People who have been diagnosed with PTSD according to standard diagnostic criteria, with a symptom checklist score above 33. - People who have not changed their psychiatric medications or supportive talk therapy in the month before their f...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06548126 · Arizona State University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 15 June 2026
🇺🇸 US

**Who might be able to join this trial:** - The adult is the primary caregiver of a child aged 6 to 12 years, and that child lives with them at least half of the time - The primary caregiver is at least 18 years old - The primary caregiver is able to participate in a program and answer questions in English, Spanish, A...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06549777 · Monique Pfaltz Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 November 2026
🇸🇪 SE

**Who might be able to join this trial:** - You are 18 years of age or older. - You can read and communicate in Swedish. - You have access to a computer and the internet. - You have a history of childhood mistreatment (such as emotional, physical, or sexual abuse or neglect), based on your answers to a specific questio...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06552832 · University of Lausanne Hospitals Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 September 2025
🇨🇭 CH

**Who might be able to join this trial:** - You speak French and are the biological child living with your mother **Who may not be able to join:** - You have a physical and/or mental disability that could make it difficult to take part in play activities or assessments - You have an active psychotic illness (a serious...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06570213 · Rush University Medical Center Early Phase 1 · 1 country Recruiting
Recruiting Early Phase 1 Est. completion 31 December 2029
🇺🇸 US

**Who might be able to join this trial:** - You are 18 years old or older - You speak and understand English fluently - You have experienced at least one traumatic event in your lifetime - You have been formally diagnosed with PTSD, confirmed through a specific clinician-led assessment - You have never previously recei...

Early Phase 1 studies are small, early exploratory studies that come before the main Phase 1 to 3 testing, so a standard phase success rate does not apply.
NCT06573970 · VA Office of Research and Development Phase 4 · 1 country Recruiting
Recruiting Phase 4 Est. completion 29 June 2029
🇺🇸 US

Who might be able to join this trial: - Military veterans between the ages of 18 and 75 who have both PTSD and Attention Deficit Disorder (ADHD), confirmed by specific symptom rating scores appropriate for their age group - People who are in good enough physical health to take part in the study - People who are able to...

Phase 4 trials study a drug that has already been approved, monitoring long-term safety and effectiveness in real-world use.
NCT06577636 · Stanford University Phase 2 · 1 country Recruiting
Recruiting Phase 2 Est. completion 1 December 2026
🇺🇸 US

**Who might be able to join this trial:** - You are between 18 and 70 years old (male or female) - You are able to read, understand, and sign a consent form before the study begins - You have been diagnosed with PTSD, confirmed through a structured interview with trained study staff - Your PTSD symptoms score above a...

Phase 2: ~30% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT06588309 · IrisZorg Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 October 2025
🇳🇱 NL

**Who might be able to join this trial:** - People who are 18 years of age or older. - People who have a primary diagnosis of substance use disorder involving alcohol, cannabis, cocaine, amphetamine, benzodiazepines, or opioids (as defined by DSM-5 criteria), and who are currently receiving or about to start outpatien...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06589505 · Otsuka Medical Devices Co., Ltd. Japan Phase 3 · 1 country Recruiting
Recruiting Phase 3 Est. completion 31 January 2028
🇯🇵 JP

Who might be able to join this trial: - You have been diagnosed with Post-Traumatic Stress Disorder (PTSD) based on current medical guidelines (DSM-5) - Your PTSD is linked to a traumatic event that happened between 1 and 20 years ago Who may not be able to join: - You have been diagnosed with schizophrenia, schizoaff...

Phase 3: ~65% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT06592677 · Norwegian Center for Violence and Traumatic Stress Studies Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 December 2027
🇳🇴 NO

**Who might be able to join this trial:** - You are currently receiving support from a local/municipal crisis team - You have experienced a deeply distressing or traumatic event within the last seven weeks before joining the trial - You scored 10 or higher on a standard checklist used to measure post-traumatic stress s...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06608277 · Northwestern University Phase 2 · 1 country Recruiting
Recruiting Phase 2 Est. completion 30 December 2027
🇺🇸 US

**Who might be able to join this trial:** - Adults aged 18 years or older - People whose medications for TBI (traumatic brain injury) and/or PTSD have been at a stable dose for more than 2 weeks - People with TBI-related headaches (with or without PTSD) who score 53 or higher on a headache impact questionnaire called...

Phase 2: ~30% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT06608706 · Haukeland University Hospital Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 December 2027
🇳🇴 NO

Who might be able to join this trial: - People aged 16 years or older - People who have been diagnosed with a psychotic disorder (such as schizophrenia or a related condition) confirmed through a structured clinical interview - People who have experienced a traumatic event that happened more than 1 month before the ass...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06629064 · VA Office of Research and Development Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 September 2028
🇺🇸 US

Who might be able to join this trial: - People who are fluent in English - People who have been diagnosed with Post-Traumatic Stress Disorder (PTSD) according to current diagnostic guidelines (DSM-5) - People who are willing to attend 8 remote (online) memory training sessions spread across four weeks - People who are...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06630884 · University of California, San Francisco Phase 1 · 1 country Recruiting
Recruiting Phase 1 Est. completion 1 November 2028
🇺🇸 US

Who might be able to join this trial: - People who are between 18 and 60 years old - People who have been exposed to a traumatic event - People who currently have PTSD, or people who have never had PTSD (both groups are being studied) Who may not be able to join: - People who have a medical reason they cannot receive...

Phase 1: ~10% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT06633146 · Joint Authority for Päijät-Häme Social and Health Care Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 December 2026
🇫🇮 FI

**Who might be able to join this trial:** - People who are experiencing an acute stroke (a stroke that is happening or has just happened recently) **Who may not be able to join:** - People whose brain bleeding was caused by a head injury rather than a stroke - People who have a serious, fast-growing (malignant) illnes...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06635486 · Boston Medical Center Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 June 2027
🇵🇪 PE

**Who might be able to join this trial:** - You are Venezuelan by nationality - You arrived in Lima (Peru) between 2014 and now - You are 18 years of age or older - You also meet at least ONE of the following: - You scored 10 or more on a standard depression questionnaire called the PHQ-9, OR - You scored 10 or mor...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06636786 · University of North Carolina, Chapel Hill Phase 2 · 1 country Recruiting
Recruiting Phase 2 Est. completion 1 September 2026
🇺🇸 US

**Who might be able to join this trial:** - You are between 18 and 55 years old - You came to the emergency department (ED) within 72 hours of being in a motor vehicle crash (car accident) - You are expected to be sent home from the ED (not admitted to the hospital) - You are willing and able to follow all study requi...

Phase 2: ~30% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT06639061 · Tel Aviv University Phase 2 · 1 country Recruiting
Recruiting Phase 2 Est. completion 1 October 2027
🇮🇱 IL

**Who might be able to join this trial:** - People aged between 20 and 65 years old. - People who have been diagnosed with PTSD according to the DSM-5 standard, confirmed through a specific structured clinical interview called the CAPS-5. - People whose CAPS-5 interview score is 33 or higher. - People who experience i...

Phase 2: ~30% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT06641115 · Medical University of South Carolina Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 August 2027
🇺🇸 US

**Who might be able to join this trial:** - People of any gender, race, or ethnicity between 18 and 70 years old - People who speak English - People who have been diagnosed with Opioid Use Disorder (OUD) — a condition involving dependence on opioids — according to standard diagnostic guidelines (DSM-5) - People who hav...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06642636 · Denzel Drop Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 December 2025
🇳🇱 NL

**Who might be able to join this trial:** - People who are currently on the waiting list for a lung transplant - People aged between 18 and 71 years old (71 is the maximum age for lung transplantation) - People who are able to understand the Dutch language - People who have read and signed a consent form agreeing to ta...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06664333 · Assistance Publique - Hôpitaux de Paris Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 21 December 2027
🇫🇷 FR

Who might be able to join this trial: - Children and adolescents between 9 and 18 years old - People whose brother or sister is currently admitted to the pediatric intensive care unit at Necker-Enfants Malades hospital or Robert Debré hospital - People whose parents or legal guardians have agreed to participate, and wh...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06670079 · University of Vermont Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 15 July 2027
🇺🇸 US

Who might be able to join this trial: - People who are female - People who are over 18 years old - People who are 25 weeks pregnant or less - People who have been diagnosed with post-traumatic stress disorder (PTSD) based on a structured clinical interview using specific diagnostic guidelines (DSM-5) - People who take...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06679062 · Pharmacotherapies for Alcohol and Substance Use Disorders Alliance Phase 2 · 1 country Recruiting
Recruiting Phase 2 Est. completion 1 March 2027
🇺🇸 US

**Who might be able to join this trial:** - You are between 21 and 65 years old. - You have been diagnosed with moderate or severe Alcohol Use Disorder (a problematic pattern of heavy drinking) within the past 12 months. - You are currently experiencing PTSD symptoms above a certain level, as measured by a standard qu...

Phase 2: ~30% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT06689254 · Christiaan Vinkers Phase 2 · 1 country Recruiting
Recruiting Phase 2 Est. completion 15 September 2026
🇳🇱 NL

**Who might be able to join this trial:** - People who speak and understand Dutch fluently - People who are 18 years of age or older and are able to provide written consent to participate - People who agree to be randomly assigned to a treatment group - People who have been diagnosed with PTSD (Post-Traumatic Stress D...

Phase 2: ~30% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT06691347 · Vestre Viken Hospital Trust Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 October 2028
🇳🇴 NO

Who might be able to join this trial: - You are 18 years old or older - You have been assessed by a clinician and diagnosed with PTSD, scoring 23 or above on a standard PTSD assessment tool called the CAPS-5 Who may not be able to join: - You do not have a good enough understanding of the Norwegian language to partici...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06700590 · ARQ National Psychotrauma Centre Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 April 2028
🇳🇱 NL

Who might be able to join this trial: - You are 18 years old or older - You have been diagnosed with PTSD based on a standard psychiatric assessment (DSM-5 criteria) - Your PTSD developed as a result of 2 or more traumatic events - You are seeking treatment for PTSD for the first time, or have had fewer than 8 therapy...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06705296 · Sunnybrook Health Sciences Centre Phase 1 · 1 country Recruiting
Recruiting Phase 1 Est. completion 1 November 2026
🇨🇦 CA

**Who might be able to join this trial:** - People aged 18 to 70 years, of any gender - People who have been diagnosed with post-traumatic stress disorder (PTSD) according to current standard diagnostic guidelines (DSM-5) - People whose PTSD has not improved despite trying at least four types of treatment, including an...

Phase 1: ~10% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT06706323 · Roland von Känel Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 April 2027
🇨🇭 CH

**Who might be able to join this trial:** - People who are scheduled for a planned (non-emergency) heart bypass surgery, either on its own or combined with a heart valve procedure - Adults aged between 18 and 90 years, both men and women - People who can read and understand the German language well enough to follow the...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06718387 · Centre Hospitalier Charles Perrens, Bordeaux Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 September 2026
🇫🇷 FR

Who might be able to join this trial: - People who are being treated at the CRP (a care or rehabilitation centre) and have experienced sexual violence - People whose CRP therapist has suggested they take part in the trial Who may not be able to join: - No specific exclusion criteria have been listed for this trial (co...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06723743 · Baylor College of Medicine Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 July 2027
🇺🇸 US

Who might be able to join this trial: - People between the ages of 25 and 64 - People who are right-handed - Veterans who were deployed as part of Operation Iraqi Freedom (OIF), Operation Enduring Freedom (OEF), Operation New Dawn (OND), or other post-9/11 war on terrorism operations - People with a history of PTSD and...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06733376 · Rush University Medical Center Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 June 2029
🇺🇸 US

**Who might be able to join this trial:** - People who are 18 years of age or older - People who are fluent in English - People who have experienced at least one traumatic event during their lifetime that meets a specific clinical definition (confirm with trial site) - People who have been diagnosed with PTSD, confirm...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06733974 · Assistance Publique - Hôpitaux de Paris Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 June 2027
🇫🇷 FR

**Who might be able to join this trial:** - People who are a family member or close relative of a patient who is dying in the emergency department, where the patient is not expected to live more than 72 hours and has a do-not-resuscitate or treatment withdrawal order in place - If several relatives are present, the tr...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06740487 · Wayne State University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 June 2027
🇺🇸 US

**Who might be able to join this trial:** - Adults aged 18 or older who have served, or are currently serving, in the military. - People who have been formally diagnosed with PTSD through a structured clinical interview called the CAPS-5 (a standardised assessment used by clinicians to diagnose PTSD). **Who may not be...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06755710 · Herlev and Gentofte Hospital Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 29 February 2028
🇩🇰 DK

Who might be able to join this trial: **For the Psychotherapeutic Unit part of the trial:** - Adults aged 18 or older - People who have been diagnosed with PTSD (post-traumatic stress disorder) according to standard diagnostic guidelines (ICD-10) - People who have signed a form agreeing to take part in the trial - Peo...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06770998 · Foundation for Atlanta Veterans Education and Research, Inc. Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 June 2027
🇺🇸 US

**Who might be able to join this trial:** - People aged 18 to 65 years old - People of any gender, including those who are gender-nonconforming - People who have received a confirmed PTSD diagnosis through a structured clinical interview and chart review - People whose PTSD symptoms are at or above a certain level of...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06773338 · Tilburg University Not Applicable · 2 countries Recruiting
Recruiting Not Applicable Est. completion 7 December 2025
🇬🇷 GR🇳🇱 NL

Who might be able to join this trial: - You speak Arabic as your language and have moved to either Greece or the Netherlands as an immigrant. - You have applied for asylum in Greece or the Netherlands at some point, no matter what the result of that application was. - You can join whether your asylum was approved, reje...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06776523 · University of Zurich Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 December 2026
🇨🇭 CH

Who might be able to join this trial: - People who are refugees or asylum seekers aged 16 or older - People who are living in one of the participating Swiss towns or transitional asylum centres where the PM+ program is being offered - People who speak at least one of these 12 languages: German, English, French, Arabic,...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06806267 · Malek Bajbouj Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 28 February 2027
🇩🇪 DE

Who might be able to join this trial: - People who are between 18 and 75 years old at the time of signing the consent form. - People who have been diagnosed with PTSD based on a structured clinical assessment, with symptoms that meet a minimum severity level at both the screening and baseline visits, and whose scores r...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06826937 · Ben-Gurion University of the Negev Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 December 2030
🇮🇱 IL

**Who might be able to join this trial:** - You have been diagnosed with PTSD and scored 25 or higher on a standard clinical PTSD assessment, indicating severe PTSD. - You are currently taking certain approved medications (such as antidepressants, trazodone, some antipsychotics, prazosin, or clonidine) and have been o...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06834867 · Possible Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 29 January 2027
Nepal

**Who might be able to join this trial:** - Married women between the ages of 15 and 24, along with their husbands and mothers-in-law, all living in the same household - Living in the local area and not planning to move away during the study - Able to speak Maithili or Nepali - The wife has experienced physical violenc...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06852469 · VA Office of Research and Development Phase 4 · 1 country Recruiting
Recruiting Phase 4 Est. completion 30 June 2029
🇺🇸 US

**Who might be able to join this trial:** - People who are military veterans - People between the ages of 18 and 65 (inclusive) - People who are willing to avoid alcohol for 24 hours before and 24 hours after the study session - People who are willing to give written consent and follow the study's requirements - *(For...

Phase 4 trials study a drug that has already been approved, monitoring long-term safety and effectiveness in real-world use.
NCT06853912 · Nathan Brashares Sackett Phase 2 · 1 country Recruiting
Recruiting Phase 2 Est. completion 1 June 2026
🇺🇸 US

**Who might be able to join this trial:** - Adults between the ages of 21 and 65 who have been diagnosed with both alcohol use disorder (AUD) and post-traumatic stress disorder (PTSD), confirmed through standard assessment tools. - People who are either a US military Veteran or currently working as a first responder,...

Phase 2: ~30% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT06854328 · GrayMatters Health Ltd. Not Applicable · 2 countries Recruiting
Recruiting Not Applicable Est. completion 1 August 2026
🇮🇱 IL🇺🇸 US

**Who might be able to join this trial:** - People aged 12 to 21 years old - People of any gender - People who have been diagnosed with PTSD (Post-Traumatic Stress Disorder) according to the standard medical guidelines (DSM-5) - People for whom at least 1 year has passed since the traumatic event that led to their PTS...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06856057 · Medical University of South Carolina Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 August 2028
🇺🇸 US

**Who might be able to join this trial:** - You are a caregiver aged 18 or older of a child who has been hospitalised due to a physical injury - The child who was injured is under 12 years old - Either the child (aged 8–11) or the caregiver has scored positively on a screening questionnaire that measures signs of acute...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06876740 · University of Colorado, Denver Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 14 June 2028
🇺🇸 US

**Who might be able to join this trial:** - You are 18 years of age or older - You own at least one firearm - You have personally experienced one or more traumatic events, such as physical assault, sexual assault, combat, or captivity - You have screened positive for PTSD symptoms using a standard screening tool (confi...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06886841 · Laurent Gaucher Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 August 2025
🇨🇭 CH

**Who might be able to join this trial:** - Women who give birth at a participating maternity unit or birth center during the study period. - The partner of a participating woman, as long as they are chosen by the mother, live with her at the time of the birth, and only one partner per mother can take part. - The birth...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06888128 · Baylor College of Medicine Phase 2 · 1 country Recruiting
Recruiting Phase 2 Est. completion 15 December 2026
🇺🇸 US

**Who might be able to join this trial:** - People who are United States Military Veterans - People who have completed at least a high school education or the equivalent (such as a GED) - People who have a current diagnosis of Post-Traumatic Stress Disorder (PTSD) according to standard diagnostic criteria (DSM-5) - Pe...

Phase 2: ~30% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT06892028 · Wave Neuroscience Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 December 2025
🇺🇸 US

Who might be able to join this trial: - You are willing and able to sign a consent form agreeing to take part in the study - You are between 22 and 65 years old - You have been diagnosed with PTSD based on a standard clinical assessment (called the CAPS) - Your PTSD symptoms have been present for at least 6 months befo...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06900712 · Case Western Reserve University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 August 2026
🇺🇸 US

**Who might be able to join this trial:** - People aged 18 to 65 years old - People who have experienced unwanted sexual contact or sexual assault, where the event happened at least 12 weeks ago but no more than 5 years ago - People who currently live in the state of Ohio - People who are experiencing at least moderate...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06902974 · Sunstone Medical Phase 2 · 1 country Recruiting
Recruiting Phase 2 Est. completion 1 November 2027
🇺🇸 US

**Who might be able to join this trial:** - Women who identify as cisgender and are at least 18 years old. - People who have been diagnosed with PTSD (post-traumatic stress disorder) caused by sexual assault, where the assault happened at least 6 months ago. - People whose PTSD symptoms score 25 or higher on a standar...

Phase 2: ~30% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT06903819 · Texas Tech University Health Sciences Center Phase 4 · 1 country Recruiting
Recruiting Phase 4 Est. completion 1 May 2027
🇺🇸 US

Who might be able to join this trial: - Adults between the ages of 18 and 65 - People who are having urgent surgery to repair a bone or muscle injury - People whose injuries are considered serious, based on a standardized injury scoring system called the Injury Severity Score being greater than 15 (confirm with trial s...

Phase 4 trials study a drug that has already been approved, monitoring long-term safety and effectiveness in real-world use.
NCT06906185 · VA Office of Research and Development Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 29 September 2028
🇺🇸 US

Who might be able to join this trial: - People who are currently pregnant (at any stage of pregnancy) - People who have experienced at least one traumatic event, as identified by a standard trauma screening tool - People who are experiencing elevated levels of anxiety or depression symptoms, as measured by brief screen...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06906302 · Boston University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 January 2030
🇺🇸 US

Who might be able to join this trial: - You receive healthcare at a participating clinic or an affiliated community-based outpatient clinic - You have experienced physical, emotional, and/or sexual abuse from a partner or spouse in the past year, as identified through a standard screening questionnaire - You are able t...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06907030 · Direction Centrale du Service de Santé des Armées Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 July 2025
🇫🇷 FR

Who might be able to join this trial: - You are a member of the military - You are permanently based/stationed in New Caledonia (NC) at the time of the study Who may not be able to join: - You are only temporarily assigned to New Caledonia (NC) at the time of the study - You are pregnant, in labour, or currently breas...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06918899 · Istanbul University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 June 2025
Turkey (Türkiye)

Who might be able to join this trial: - People who have experienced at least one traumatic event in their life - Children or teenagers between the ages of 7 and 18 - Families where the child and/or their parents or caregivers can read and communicate adequately in Turkish Who may not be able to join: - Children or par...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06923423 · University of Arkansas Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 December 2028
🇺🇸 US

**Who might be able to join this trial:** - People who are 18 years of age or older - People who can speak and understand English - People who are able to give informed consent to participate - People who are currently held in one of the prisons that have partnered with this study - People who met the criteria for a dr...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06925867 · Ohio State University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 14 February 2028
🇺🇸 US

**Who might be able to join this trial:** - People who are 18 years of age or older - People who have been diagnosed with PTSD, or who have a partial form of PTSD that includes at least 3 out of 4 symptoms, one of which must be hyperarousal (a state of being constantly on high alert — confirm with trial site if unsure...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06926296 · Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 July 2026
🇫🇷 FR

"Who might be able to join this trial: - People who work as healthcare workers. Who may not be able to join: - People who have not given their consent to participate in the trial. Important: Always verify eligibility with the trial site directly before applying."

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06931093 · Peking University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 10 March 2026
🇨🇳 CN

**Who might be able to join this trial:** - Be between 10 and 18 years old - Have symptoms that meet the criteria for Complex PTSD (C-PTSD), meaning they experience at least one symptom from each of the trauma-related symptom groups, as well as difficulties with emotions, relationships, or sense of self (confirm with t...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06937892 · Karolinska Institutet Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 December 2028
🇸🇪 SE

**Who might be able to join this trial:** - You are 18 years of age or older - Your main or most troublesome diagnosis is Generalised Anxiety Disorder (GAD), Social Anxiety Disorder (SAD), or Post-Traumatic Stress Disorder (PTSD) - If you are taking medication, your dose has not changed in the last six weeks - You are...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06943560 · Tel Aviv University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 December 2025
🇮🇱 IL

Who might be able to join this trial: - People whose first language is Hebrew - People aged between 18 and 65 years old - People with normal vision, or vision that is corrected to normal (for example, with glasses or contact lenses) - People who have access to a computer and the internet - People who meet the DSM-5 dia...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06944262 · Lille University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 5 February 2027
🇫🇷 FR

**Who might be able to join this trial:** **For patients (Part 1):** - Adults aged 18 or older - People diagnosed with breast, gynaecological, testicular, or digestive cancer within the last 4 months, at the point when their treatment plan was first explained to them - People whose cancer requires active cancer treatm...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06947538 · Boston Medical Center Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 June 2029
🇺🇸 US

**Who might be able to join this trial:** - People who receive primary care at Boston Medical Center - People who are at least 18 years old - People who have access to a computer or mobile device - People who are able to receive treatment in English or Spanish - People who can read at around a 4th grade level - People...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06952933 · Dartmouth-Hitchcock Medical Center Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 June 2026
🇺🇸 US

Who might be able to join this trial: - People who have been diagnosed with congenital heart disease (a heart condition present from birth) and are 18 years of age or older - People who are already enrolled in the CHI (Congenital Heart International) registry - People who are sufficiently proficient in English to compl...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06953687 · The University of Texas Health Science Center at San Antonio Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 September 2027
🇺🇸 US

Who might be able to join this trial: - Active duty military service members who are 18 years of age or older. - People who have been assessed by a clinician and diagnosed with PTSD using a standardised diagnostic interview tool. Who may not be able to join: - People who are currently having thoughts of suicide or har...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06956781 · University of Rochester Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 August 2028
🇺🇸 US

**Who might be able to join this trial:** - Your child is between 8 and 17 years old and has experienced at least one traumatic event - Your child has been diagnosed with PTSD (post-traumatic stress disorder) as a result of one or more of those traumatic experiences - Your child agrees and is willing to take part in t...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06957067 · United States Department of Defense Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 May 2028
🇺🇸 US

Who might be able to join this trial: - People who are veterans seeking outpatient PTSD therapy through the VA - People who have been diagnosed with PTSD according to standard diagnostic criteria (DSM-5) - People who are able to give informed consent to participate - People who are willing to be randomly assigned to a...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06968312 · Tel Aviv University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 September 2026
🇮🇱 IL

Who might be able to join this trial: - People who have been diagnosed with PTSD (Post-Traumatic Stress Disorder) based on standard diagnostic guidelines known as DSM-5 - People aged 18 years or older - People whose treating doctor has determined them eligible for a specific trauma-focused therapy called CPT (Cognitive...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06968832 · Rutgers, The State University of New Jersey Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 June 2029
🇺🇸 US

**Who might be able to join this trial:** - You are 18 years of age or older - You are currently enrolled in substance use disorder (addiction) treatment at Gateway Community Services - You have been diagnosed with a substance use disorder (a problem with drugs or alcohol) — please note that tobacco use alone does not...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06975280 · Theodora Anastasiou Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 December 2025
🇬🇷 GR

**Who might be able to join this trial:** - You arrived in Greece alone (without a parent or guardian) and are between 15 and 18 years old - You have been diagnosed with PTSD according to standard diagnostic guidelines, OR you have shown moderate or high levels of trauma-related stress based on a standard screening too...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06975852 · Istanbul University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 18 July 2025
Turkey (Türkiye)

Who might be able to join this trial: - Children and teenagers between 7 and 18 years old who experienced at least one traumatic event and who took part in a related research study approximately one year ago (between January and April 2024) - Children, teenagers, and/or their parents or guardians who can read and commu...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06988787 · Icahn School of Medicine at Mount Sinai Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 August 2028
🇺🇸 US

Who might be able to join this trial: - People who are able to give informed consent (as measured by a specific assessment tool), speak English, are female veterans, and are 18 years of age or older - People who screen positive for exposure to intimate partner violence (IPV) and/or military sexual trauma (MST) using st...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT06989957 · Johns Hopkins University Phase 1 · 1 country Recruiting
Recruiting Phase 1 Est. completion 1 August 2028
🇺🇸 US

**Who might be able to join this trial:** - People who are 21 years of age or older - People who are military veterans - People who have provided written consent to take part in the trial - People who are able to swallow pills - People who have a confirmed diagnosis of Post-Traumatic Stress Disorder (PTSD) lasting at...

Phase 1: ~10% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT06990191 · United States Department of Defense Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 August 2028
🇺🇸 US

**Who might be able to join this trial:** - You are a Veteran who served after September 11, 2001 and receive care through the VA health system - Your medications have been stable for more than one month - You have been in a committed relationship for at least 6 months - You have been diagnosed with PTSD based on curre...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07010757 · VA Office of Research and Development Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 2 March 2029
🇺🇸 US

**Who might be able to join this trial:** - People who are military veterans and are 18 years of age or older - People who have a current diagnosis of PTSD, confirmed using a specific clinical assessment tool called the CAPS-5-R - People with a body mass index (BMI) of 30 or higher, which is the medical threshold for o...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07010770 · VA Office of Research and Development Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 May 2030
🇺🇸 US

Who might be able to join this trial: - People who are licensed mental health clinicians, or mental health trainees working within the VA system (such as practicum students, psychology interns, or postdoctoral fellows), whose regular job duties include providing therapy services to Veterans - People who are able to com...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07011940 · Oregon Research Behavioral Intervention Strategies, Inc. Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 August 2027
🇺🇸 US

Who might be able to join this trial: - People who are within the first month of experiencing a pregnancy or early infant loss - People who live in the United States - People who can speak and read English or Spanish at around a 6th grade reading level - People who are 15 years old or older Who may not be able to join...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07015567 · Eva Heim Not Applicable · 2 countries Recruiting
Recruiting Not Applicable Est. completion 1 December 2030
🇩🇪 DE🇨🇭 CH

Who might be able to join this trial: - People who have signed a consent form agreeing to take part in the study - Refugees or asylum seekers who hold a valid residence permit (with an N, F, B, or C status) - People who speak Arabic, Farsi/Dari, Pashtu, Kurdish (any dialect), or Turkish - People for whom a mental healt...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07021352 · United States Naval Medical Center, San Diego Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 October 2027
🇺🇸 US

Who might be able to join this trial: - People who are currently serving in the military or have previously served as a veteran - People who scored 14 or above on a short PTSD symptom checklist called the PCL 6-item - People who scored 24 or above on a scale called the EDS (confirm with trial site for details on what t...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07033741 · University of Turin, Italy Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 December 2027
🇮🇹 IT

Who might be able to join this trial: **Therapists:** - Therapists who are certified members of the Italian EMDR (Eye Movement Desensitization and Reprocessing) Association may be eligible to participate. **Patients:** - Adults aged 18 years or older may be eligible to participate. - People who are able to understand...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07040462 · Beykoz University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 15 October 2025
Turkey (Türkiye)

**Who might be able to join this trial:** - Children who were between 3 and 6 years old at the time of joining the study - Children who lived in one of the 11 cities affected by the 2023 Kahramanmaraş earthquake, such as Hatay, Kahramanmaraş, Adıyaman, Malatya, Gaziantep, Şanlıurfa, Adana, Osmaniye, Diyarbakır, Kilis,...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07052474 · Karolinska Institutet Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 October 2025
🇸🇪 SE

**Who might be able to join this trial:** - You are between 13 and 17 years old and have been diagnosed with PTSD (Post-Traumatic Stress Disorder) - You are either not taking any medication, or you are on a stable dose of antidepressants, stimulants, and/or antipsychotics - At least one parent or caregiver is able to t...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07055373 · University of Calgary Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 January 2027
🇨🇦 CA

**Who might be able to join this trial:** - People whose symptoms started at least 3 months ago but less than 10 years ago - People whose whiplash injury has been classified as Grade I (neck pain only), Grade II (neck pain with reduced movement or tenderness), or Grade III (neck pain with signs of nerve involvement fou...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07055633 · VA Office of Research and Development Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 September 2030
🇺🇸 US

Who might be able to join this trial: - People who served in the US military after September 11, 2001, and are currently enrolled at VA San Diego or VA Portland - People who are able to give their informed consent to participate - People who are living independently (not in a care facility) - People who have a confirme...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07060144 · University of Texas at Austin Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 May 2027
🇺🇸 US

Who might be able to join this trial: - People who are female and between 18 and 46 years old - People who are currently pregnant and less than 25 weeks along - People who are able to read and write in English - People who have experienced at least one traumatic event that meets a specific clinical definition (confirm...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07062042 · Kristiania University College Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 20 December 2025
🇳🇴 NO

Who might be able to join this trial: - People who are Ukrainian refugees currently living in Norway - People who arrived in Norway after 24 February 2022 - People who are at least 18 years old - People who have agreed to participate by giving their informed consent - People who, based on screening questionnaires, show...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07069517 · Palo Alto Veterans Institute for Research Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 December 2028
🇺🇸 US

**Who might be able to join this trial:** - You are active-duty military or a veteran between 18 and 65 years old who is eligible through the Defense Enrollment Eligibility Reporting System (DEERS) (confirm with trial site if unsure about DEERS eligibility) - You are able to speak and read English - You have been asses...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07071350 · Virginia Commonwealth University Phase 3 · 1 country Recruiting
Recruiting Phase 3 Est. completion 1 September 2028
🇺🇸 US

**Who might be able to join this trial:** - You are 18 years old or older - You have served in the military at some point in your life - You have had at least one mild traumatic brain injury (concussion) in your past - Your most recent brain injury happened more than one year ago - You are currently experiencing a sign...

Phase 3: ~65% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT07079761 · Massachusetts General Hospital Phase 2 · 1 country Recruiting
Recruiting Phase 2 Est. completion 30 April 2027
🇺🇸 US

**Who might be able to join this trial:** - People aged 18 to 55 at the time of joining, who are reproductively mature and speak English. - People who have been diagnosed with chronic PTSD, meaning their PTSD has lasted more than 3 months, as confirmed by a clinical assessment tool called the CAPS-5. - People who are...

Phase 2: ~30% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT07079839 · The University of Texas Health Science Center, Houston Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 July 2026
🇺🇸 US

Who might be able to join this trial: - People who are right-handed - People who have normal vision, or vision that is fully corrected with glasses or contact lenses, and a normal sense of smell - People who are between 18 and 50 years old - People who pass a safety screening checklist for a brain stimulation procedure...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07104916 · Anthony P King Phase 2 · 1 country Recruiting
Recruiting Phase 2 Est. completion 1 September 2029
🇺🇸 US

**Who might be able to join this trial:** - People who were assigned female or male at birth. - People aged between 21 and 65 years old at the time of screening. - People with a body mass index (a measure of body weight relative to height) between 18 and 30 at the time of screening. - People who have been formally dia...

Phase 2: ~30% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT07107269 · Colorado State University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 June 2026
🇺🇸 US

**Who might be able to join this trial:** - Adults aged 18 to 65 who have been diagnosed with PTSD - People with a Body Mass Index (BMI) under 35 (a measure of body weight relative to height) - People who are in general good health aside from their PTSD diagnosis - People who are willing and able to follow the study sc...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07115030 · Yale University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 August 2029
🇺🇸 US

**Who might be able to join this trial:** - Women aged 18 or older - People currently receiving medication treatment for opioid use disorder (MOUD) at one of the participating clinics - People who have been on this medication treatment for more than 14 days - People who started their current treatment episode within th...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07115186 · Peking University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 June 2026
🇨🇳 CN

Who might be able to join this trial: - People who are currently enrolled in middle school and attending regular classes - People who have enough ability to hear, speak, read, and write to take part in the study activities and assessments Who may not be able to join: - People who have been assessed as being at high ri...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07116109 · The University of Texas Health Science Center, Houston Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 January 2029
🇺🇸 US

**Who might be able to join this trial:** - People who have ongoing musculoskeletal pain (such as pain in muscles, joints, or bones) that is not related to cancer, has lasted at least six months, rates 3 or higher on a 0–10 pain scale, and significantly interferes with daily life, with a confirmed diagnosis recorded i...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07118839 · VA Office of Research and Development Phase 3 · 1 country Recruiting
Recruiting Phase 3 Est. completion 1 May 2030
🇺🇸 US

**Who might be able to join this trial:** - People who are at least 18 years old at the time of signing the consent form - People who are currently receiving care through the VA (Veterans Affairs) system - Veterans who have already tried and stopped (or finished) at least one recommended treatment for PTSD, for both P...

Phase 3: ~65% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT07146633 · Centre for Addiction and Mental Health Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 January 2027
🇨🇦 CA

Who might be able to join this trial: - You are 18 years old or older - You are fluent in English - You have been diagnosed with PTSD, confirmed by a specific questionnaire called the PCL-5 with a score above 32 in the past month - You have been diagnosed with a substance use disorder (such as alcohol or drug misuse) w...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07164105 · Laureate Institute for Brain Research, Inc. Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 August 2028
🇺🇸 US

**Who might be able to join this trial:** - You work in a frontline healthcare role, such as emergency medical services - You are between 18 and 65 years old - You have scored within a certain range on a standard PTSD questionnaire (PCL-5 score of 33 or above but below 65), or you have been assessed as having at least...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07165782 · IWK Health Centre Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 10 September 2026
🇨🇦 CA

Who might be able to join this trial: - People who score at least 31 on a standard PTSD checklist, suggesting they may have PTSD - People who have been directly or indirectly exposed to a traumatic event, such as actual or threatened death, serious injury, or sexual violence — this includes witnessing it, experiencing...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07165834 · Sykehuset Telemark Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 September 2026
🇳🇴 NO

Who might be able to join this trial: - You have experienced sexual trauma at some point in your life - You are currently dealing with sexual problems that are connected to that trauma - You are between 18 and 65 years old - You are able to understand and communicate in Norwegian well enough to take part in a group edu...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07175025 · Indiana University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 December 2027
🇺🇸 US

**Who might be able to join this trial:** - You are 18 years of age or older - You are able to read and speak English - You have been assessed as likely having PTSD based on a standard checklist (called the PCL-5) - You are currently pregnant, or you have given birth within the last 12 weeks **Who may not be able to j...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07176273 · The University of Texas Health Science Center at San Antonio Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 22 May 2028
🇺🇸 US

**Who might be able to join this trial:** - You must be a Veteran who is eligible to receive PTSD therapy at the clinic taking part in this study - You must be 18 years old or older - You must score 31 or higher on a standard PTSD symptom checklist (called the PCL-5), linked to a traumatic event you have experienced -...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07185126 · Viktoriia Gorbunova Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 20 February 2026
🇺🇦 UA

**Who might be able to join this trial:** - Children who are between 6 and 14 years old at the time of joining the trial. - Children whose parent or guardian-completed screening questionnaire (called the CATS-2) shows a total score of 15 or higher, indicating the presence of trauma-related stress symptoms. - Children...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07193914 · Centre Hospitalier Universitaire de Nīmes Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 March 2027
🇫🇷 FR

**Who might be able to join this trial:** - People who have one or more addictions - People whose results on a substance use questionnaire (called the ASSIST) reach a certain level — a score of 11 or higher for alcohol, or 4 or higher for other substances - People who have been assessed and diagnosed with PTSD (post-tr...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07196332 · University of North Carolina, Chapel Hill Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 September 2026
🇺🇸 US

**Who might be able to join this trial:** - People who are awake, alert, and aware of their surroundings at the time of screening - People who can read and speak English - People aged 18 to 65 - People who come to the emergency department within 72 hours (3 days) of being in a motor vehicle crash - People who are sent...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07197476 · Rhode Island Hospital Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 April 2027
🇺🇸 US

**Who might be able to join this trial:** *For young people (youth):* - You must be between 12 and 17 years old - You must be able to speak and understand English or Spanish - You must be able to agree to take part in the study yourself - You must have a parent or guardian who is able to give their permission for you...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07204535 · Centre Paul Strauss Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 17 November 2030
🇫🇷 FR

**Who might be able to join this trial:** - You have been diagnosed with cervical cancer and your doctors have recommended a specific type of internal radiation treatment called brachytherapy (high-dose rate or pulse-dose rate) - Your cervical cancer can be of any cell type, including squamous cell carcinoma or others...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07214415 · Summit Hyperbarics and Wellness Phase 2 · 1 country Recruiting
Recruiting Phase 2 Est. completion 15 September 2026
🇺🇸 US

**Who might be able to join this trial:** - You are at least 18 years old and no older than 75 years old. - You are a veteran. - You have been officially diagnosed by a qualified professional with a mild traumatic brain injury (mild TBI), PTSD, anxiety, or depression. - You are willing and able to read, understand, an...

Phase 2: ~30% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT07217795 · University of Rhode Island Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 November 2026
🇺🇸 US

**Who might be able to join this trial:** - This section's inclusion criteria were not publicly listed — please contact the trial site directly to find out if you qualify (confirm with trial site) **Who may not be able to join:** - People who do not meet the basic requirements to be part of the study (confirm with t...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07220681 · Veterans Medical Research Foundation Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 June 2029
🇺🇸 US

Who might be able to join this trial: - You have received a clinical diagnosis (confirm with trial site for which specific diagnosis applies) - You are eligible to receive a type of therapy called Cognitive Processing Therapy (CPT) at a participating VA location - You are able to understand and agree to take part in th...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07225049 · Weill Medical College of Cornell University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 August 2027
🇺🇸 US

**Who might be able to join this trial:** - You are 18 years of age or older - You speak English - You have been assessed and currently meet the criteria for PTSD (post-traumatic stress disorder), caused by any type of traumatic event - You have been experiencing chronic pain, meaning you have rated your pain as a 4 or...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07227337 · Johns Hopkins University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 December 2028
🇺🇸 US

Who might be able to join this trial: - You are 18 years old or older - You were born outside of the country and have moved here as an immigrant - You are a woman - You have personally experienced ongoing or repeated exposure to violence, and currently have symptoms of PTSD (post-traumatic stress) and/or depression Wh...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07238192 · Ohio State University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 November 2027
🇺🇸 US

**Who might be able to join this trial:** - You are an active duty service member or veteran aged 18 or older who is eligible for military medical care. - You are able to read, write, and speak English. - You have been assessed by a clinician and meet the criteria for PTSD or a near-full level of PTSD symptoms in the p...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07245641 · Brigham and Women's Hospital Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 November 2027
🇺🇸 US

Who might be able to join this trial: - People aged between 18 and 65 years old - People who have been diagnosed with PTSD according to standard diagnostic criteria (DSM-5), confirmed through a structured clinical assessment - People whose PTSD symptoms are at least moderate in severity, as measured by a standard sympt...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07246356 · University of Birmingham Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 June 2026
🇬🇧 GB

Who might be able to join this trial: - People aged between 18 and 65 years old. - People who are currently receiving care from the Black Country Perinatal Mental Health Service. - People who are experiencing trauma symptoms related to a birthing experience that happened within the last 18 months, including the birth i...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07250061 · Boston University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 March 2028
🇺🇸 US

Who might be able to join this trial: - People who identify as a woman - People who have served in the United States military - People who have a diagnosis of Post-Traumatic Stress Disorder (PTSD), either full or partial (meaning symptoms from at least 2 out of 4 of the main symptom groups are present) - People who can...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07260032 · Massachusetts General Hospital Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 January 2027
🇺🇸 US

**Who might be able to join this trial:** - You are between 18 and 65 years old - You have experienced a traumatic event at some point in your life - You have symptoms of PTSD (post-traumatic stress disorder) - You have either early-stage or diagnosed heart or blood vessel disease (such as a history of heart attack or...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07275970 · Suzanne "Sue" Sisley MD Phase 1 · 1 country Recruiting
Recruiting Phase 1 Est. completion 1 March 2026
🇺🇸 US

**Who might be able to join this trial:** - People aged 18 years or older - People who have been diagnosed with Post-Traumatic Stress Disorder (PTSD) for at least 6 months, confirmed by a study psychiatrist using standard diagnostic tools, with at least one identified traumatic event and a score of 33 or higher on a s...

Phase 1: ~10% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT07283757 · University of Wisconsin, Madison Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 December 2029
🇺🇸 US

"Who might be able to join this trial: - You are 18 years old or older - You are on the Department of Corrections trauma treatment waitlist - You have been assessed and do not currently have active symptoms of psychosis that would get in the way of taking part in group sessions - You do not currently have thoughts of s...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07288008 · Birmingham VA Health Care System Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 December 2027
🇺🇸 US

**Who might be able to join this trial:** - People who have served in the U.S. military as a veteran - People who speak English and are willing to sign consent and privacy forms - Adults aged 70 years or younger - People who scored 10 or higher on the GAD-7 anxiety questionnaire in the past week, which indicates at le...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07288151 · Emory University Phase 2 · 1 country Recruiting
Recruiting Phase 2 Est. completion 1 January 2030
🇺🇸 US

**Who might be able to join this trial:** - You have been diagnosed with PTSD, confirmed through a structured clinical interview. - You can speak and read English. - You are willing to allow the study team to communicate with your regular doctor or mental health provider if needed. - You are able to swallow pills. - Y...

Phase 2: ~30% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT07302334 · Karolinska Institutet Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 28 August 2026
🇸🇪 SE

Who might be able to join this trial: - People who have been diagnosed with PTSD (Post-Traumatic Stress Disorder), confirmed through medical records. - People who score above 30 on a self-reported PTSD checklist called the PCL-5, which measures PTSD symptom severity. - People who are 18 years of age or older. - People...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07302984 · The Center for Mind-Body Medicine Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 March 2026
Palestinian Territories

Who might be able to join this trial: - People who are between 11 and 17 years old and currently living in Gaza - People who have been exposed to political violence or a war-related traumatic event - People whose symptoms meet the standard diagnostic criteria for PTSD (post-traumatic stress disorder), as measured by a...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07306676 · Jagiellonian University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 December 2027
🇵🇱 PL

Who might be able to join this trial: - People who have experienced a spontaneous abortion (also called a miscarriage) - People who are up to 14 weeks into their pregnancy at the time of the miscarriage Who may not be able to join: - There are no listed exclusion criteria for this trial Important: Always verify eligi...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07306689 · Jagiellonian University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 December 2027
🇵🇱 PL

Who might be able to join this trial: - People who have been diagnosed with an ectopic pregnancy (a pregnancy that has developed outside the womb) - People whose pregnancy is 14 weeks along or less at the time of joining Who may not be able to join: - People who have a heterotopic pregnancy (a rare situation where the...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07309302 · Université du Québec a Montréal Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 December 2026
🇨🇦 CA

Who might be able to join this trial: - You are between 18 and 45 years old - You can speak and read French fluently - You have access to a computer with a camera and a reliable, secure internet connection - You have access to a private space where you can attend assessment and treatment sessions - You are available to...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07317206 · University of Sao Paulo Phase 2 · 1 country Recruiting
Recruiting Phase 2 Est. completion 1 June 2026
🇧🇷 BR

Who might be able to join this trial: - You have been diagnosed with post-traumatic stress disorder (PTSD) Who may not be able to join: - You have other mental health conditions or other medical conditions alongside your PTSD (confirm with trial site) Important: Always verify eligibility with the trial site directly...

Phase 2: ~30% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT07318181 · University of Luxembourg Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 November 2027
🇺🇦 UA

Who might be able to join this trial: - Adults between 18 and 65 years old - People who have been diagnosed with PTSD according to recognised diagnostic guidelines (DSM-5-TR or ICD-11) - People experiencing PTSD symptoms that are causing significant distress or are affecting their social life, work, or daily functionin...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07325734 · Peking University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 25 November 2026
🇨🇳 CN

**Who might be able to join this trial:** - People who are between 10 and 18 years old - People who have been assessed as meeting the diagnostic criteria, or nearly meeting the criteria, for Complex PTSD (C-PTSD) — specifically, missing no more than one symptom from either of the two main symptom groups used to define...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07334418 · University of Pennsylvania Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 November 2027
🇺🇸 US

Who might be able to join this trial: - You are a woman aged 18 or older who is having a planned (non-emergency) cesarean section (C-section) - You are receiving regional anesthesia for your C-section, such as an epidural, spinal block, or a combined spinal-epidural - You are experiencing severe pain during the surgery...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07336251 · White River Junction Veterans Affairs Medical Center Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 January 2027
🇺🇸 US

**Who might be able to join this trial:** - People aged between 19 and 70 years old - People who are eligible for VA (Veterans Affairs) healthcare - People with moderate to severe PTSD, confirmed by a specific assessment tool (called the CAPS) that scores at least 25, taken within 7 days of being enrolled in the trial...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07339891 · University Hospital, Strasbourg, France Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 June 2026
🇫🇷 FR

Who might be able to join this trial: - People who are 18 years of age or older - People who have stayed in intensive care for more than 48 hours Who may not be able to join: - People who were admitted to intensive care after a planned (scheduled) surgery - People who have been readmitted to intensive care within the...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07342530 · Stanford University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 December 2027
🇺🇸 US

Who might be able to join this trial: - People who are 18 years of age or older - People who have given birth to a live baby within the last 5 days - People who experienced a serious health complication during childbirth, or whose baby has been admitted to the newborn intensive care unit (NICU) - People who score 28 or...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07346638 · Stanford University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 August 2027
🇺🇸 US

Who might be able to join this trial: - You are a woman between the ages of 18 and 75 - You have experienced physical, sexual, and/or emotional violence in the past, and this has led to personal distress such as depression or anxiety - You are currently having thoughts of suicide Who may not be able to join: - You are...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07351305 · The University of Texas Health Science Center at San Antonio Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 March 2027
🇺🇸 US

**Who might be able to join this trial:** - You are willing and able to understand and sign a written consent form to participate in the study - You are a veteran or active duty service member aged 18 or older who has been diagnosed with a mild or moderate traumatic brain injury (TBI) - You have been diagnosed with PTS...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07368166 · University Children's Hospital, Zurich Not Applicable · 2 countries Recruiting
Recruiting Not Applicable Est. completion 31 October 2026
🇩🇪 DE🇨🇭 CH

Who might be able to join this trial: **Clinical group (patients at participating health centres):** - Children or teenagers aged 7 to 18 who are currently using mental health or general health services at a participating centre, or caregivers of children aged 3 to 18 who are using those services - Sufficient ability...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07372586 · Medical University of South Carolina Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 June 2028
🇺🇸 US

Who might be able to join this trial: - People who have attended the MUSC ICU Recovery Clinic within 180 days of being discharged from the hospital Who may not be able to join: - People whose ICU admission was primarily due to an addiction-related condition, such as alcohol withdrawal or a severe alcohol withdrawal re...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07382596 · Dr. Dean Reeves Clinic Phase 4 · 1 country Recruiting
Recruiting Phase 4 Est. completion 1 March 2030
🇺🇸 US

Who might be able to join this trial: - People who are not currently taking part in another PTSD treatment study - People who have reliable transport to get to appointments - People who are comfortable using computers - People who have tried 2 or more medications for PTSD symptoms - People who have tried 2 or more non-...

Phase 4 trials study a drug that has already been approved, monitoring long-term safety and effectiveness in real-world use.
NCT07390786 · Medical University of South Carolina Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 June 2028
🇺🇸 US

Who might be able to join this trial: - People who are a family member of a patient attending an ICU Recovery Clinic, where that patient is already enrolled in a related study called the BH CoCM study Who may not be able to join: - People who have a serious mental illness, such as schizophrenia or mania - People who h...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07396623 · Assistance Publique - Hôpitaux de Paris Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 15 August 2027
🇫🇷 FR

Who might be able to join this trial: - People who are 18 years of age or older - People who are either attending a clinic as an outpatient or currently staying in hospital for any health-related reason - People who can read and speak French well enough to communicate and understand study materials - People who have be...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07401225 · The University of Texas Health Science Center at San Antonio Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 June 2027
🇺🇸 US

Who might be able to join this trial: - People aged 12 to 20 years old, of any gender - People who have already completed at least 9 sessions of trauma-focused therapy, either through a clinical trial or in the community - People whose current PTSD symptom score is 20 or higher on a standard self-reported questionnaire...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07407946 · Umeå University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 December 2028
🇸🇪 SE

**Who might be able to join this trial:** - Young people aged 12 to 17 years - People who have been formally diagnosed with post-traumatic stress disorder (PTSD) through a structured diagnostic interview - People whose PTSD symptom score on a standardised checklist (called the CATS-2) is 25 or above at the start of the...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07410481 · Columbia University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 June 2028
🇺🇸 US

**Who might be able to join this trial:** - You are between 18 and 81 years old at the time of signing up - You are fluent in English - You have a history of cardiac arrest (heart stopping) that happened more than 3 months ago - You have been assessed by a clinician and found to have significant PTSD (post-traumatic st...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07419594 · Charite University, Berlin, Germany Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 December 2027
🇩🇪 DE

Who might be able to join this trial: - You are a healthy woman volunteering to take part - You can speak or understand German at an intermediate level (B1) Who may not be able to join: - You have been diagnosed with, or currently have, any mental health condition listed in the DSM-5 (a standard guide used by doctors...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07420478 · Dartmouth-Hitchcock Medical Center Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 December 2026
🇺🇸 US

Who might be able to join this trial: **For therapists:** - Therapists who have been working as a clinician at a publicly-funded community mental health centre for at least 6 months may be eligible to take part. - Therapists who have received training in a specific type of therapy called TF-CBT (Trauma-Focused Cogniti...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07422077 · Hôpital Européen Marseille Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 8 June 2027
🇫🇷 FR

Who might be able to join this trial: - Adults aged 18 or older - Adults who are currently admitted to a Post-Intensive Care Rehabilitation Unit (a specialised ward for recovery after intensive care) - People who have given their written agreement to take part after being fully informed about the trial Who may not be...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07430657 · Rush University Medical Center Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 June 2028
🇺🇸 US

**Who might be able to join this trial:** - You have been assessed as having PTSD symptoms, with a screening score of 28 or higher on a standard PTSD checklist, and have experienced a qualifying traumatic event confirmed through assessment tools - You have had a serious, life-threatening heart or blood vessel event in...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07456696 · Transcend Therapeutics Phase 3 · 1 country Recruiting
Recruiting Phase 3 Est. completion 1 December 2027
🇺🇸 US

**Who might be able to join this trial:** - People who have been diagnosed with PTSD (post-traumatic stress disorder) according to standard diagnostic guidelines, with symptoms lasting at least 6 months. - People who have already tried at least one medication or trauma-focused talking therapy for PTSD. - People who are...

Phase 3: ~65% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT07462312 · NeuroBrave ltd. Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 September 2026
🇮🇱 IL

Who might be able to join this trial: - People who are male and aged 18 years or older - People who have been clinically diagnosed with Post-Traumatic Stress Disorder (PTSD) with mild to moderate-severe symptoms - People whose PTSD symptom score (measured using a standard tool called the PCL-5) is 60 or below at the sc...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07469098 · Sheba Medical Center Phase 2 · 1 country Recruiting
Recruiting Phase 2 Est. completion 31 December 2028
🇮🇱 IL

Who might be able to join this trial: - People who are at least 18 years old. - People who have been diagnosed with PTSD (according to standard diagnostic guidelines) where the diagnosis was made after 7 October 2023 and relates to events from that time onwards. - People whose PTSD symptoms in the past month are rated...

Phase 2: ~30% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT07473362 · Medical Corps, Israel Defense Force Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 August 2027
🇮🇱 IL

Who might be able to join this trial: - Adults aged 18 to 80 years old - People who are able to understand the researchers' explanation of the trial and agree to participate - People of any sex or gender (the trial is making a specific effort to include women) - People who have been diagnosed with PTSD according to DSM...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07473505 · Reset Medical and Wellness Center Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 24 February 2027
🇺🇸 US

**Who might be able to join this trial:** - Adults aged 18 years or older - People who score 33 or higher on a standard PTSD symptom checklist (called the PCL) at the initial screening - People who are willing and able to agree to participate and complete all study-related tasks - People who are fluent in English - Peo...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07485231 · University of Minnesota Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 May 2028
🇺🇸 US

**Who might be able to join this trial:** - Women between the ages of 18 and 40 (biologically female) - People who are still having menstrual cycles (pre-menopausal), based on self-report - People who have experienced trauma, with or without a diagnosis of PTSD - People who have been diagnosed with major depression -...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07488819 · Yale University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 March 2031
🇺🇸 US

**Who might be able to join this trial:** - People who are willing and able to give written consent to take part in the study. - People who can read, write, and communicate clearly with the research team, and are able to follow all study instructions. - Men or women between 18 and 70 years of age at the time of screen...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07506395 · University of New Mexico Phase 1 · 1 country Recruiting
Recruiting Phase 1 Est. completion 1 May 2027
🇺🇸 US

**Who might be able to join this trial:** - People who are at least T+H years old and under 89 years old (confirm with trial site — the lower age limit appears incomplete in the source document) - People who identify as a veteran, first responder, female survivor of sexual violence, or Indigenous person - People who a...

Phase 1: ~10% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT07523685 · Acacia Clinics Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 January 2027
🇺🇸 US

Who might be able to join this trial: - People who have been diagnosed with PTSD through a structured clinical interview based on DSM-5 criteria - People whose PTSD symptom severity score on a standard assessment (called the CAPS-5) is 35 or higher - People between the ages of 18 and 70 years old - People who have curr...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07525284 · Almaviva Sante Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 December 2027
🇫🇷 FR

Who might be able to join this trial: - The person must be 18 years of age or older, either male or female - The person must have been discharged from an intensive care unit (ICU) while still alive - The person must have spent at least three calendar days in intensive care - The person must be covered by a social secur...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07548125 · Josh Cisler Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 May 2030
🇺🇸 US

**Who might be able to join this trial:** - People aged between 18 and 55 years old - People who are currently experiencing at least 4 PTSD symptoms, including at least 1 re-experiencing symptom (such as unwanted trauma memories, nightmares about trauma, flashbacks, strong emotional distress linked to trauma, or strong...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07555873 · Burim Peli Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 June 2026
Kosovo

**Who might be able to join this trial:** - You are between 18 and 65 years old. - You have been experiencing symptoms related to your neck and head area for at least three months. - You have neck pain, with or without headaches. - You feel dizzy when you move your neck or hold it in certain positions. - A clinical exa...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07558759 · Emory University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 April 2031
🇺🇸 US

**Who might be able to join this trial:** - People who are able to give written consent to participate - People who speak fluent English - People of any sex or ethnic background who are between 18 and 65 years old - People who do not currently have moderate to severe alcohol or drug use issues, based on screening quest...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07561632 · University of British Columbia Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 December 2027
🇨🇦 CA

Who might be able to join this trial: - People who are 19 years of age or older - People who have had an unplanned caesarean delivery - People who are able to give their informed agreement to take part in the study - People who can read and understand questionnaires written in English Who may not be able to join: - Pe...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07565311 · Oslo University Hospital Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 December 2027
🇳🇴 NO

Who might be able to join this trial: - You have been diagnosed with PTSD (Post-Traumatic Stress Disorder) - You are between 18 and 65 years old - You are able to read, understand, and sign a consent form agreeing to take part in the study Who may not be able to join: - You are currently misusing or abusing alcohol or...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07568145 · Emory University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 March 2028
🇺🇸 US

**Who might be able to join this trial:** - People aged 18 to 65 years old - People who have experienced a traumatic event — such as something that involved death, serious injury, or sexual violence — within the last 2 weeks - People who are currently experiencing high levels of PTSD symptoms related to that recent tra...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07569159 · Sunstone Medical Phase 2 · 1 country Recruiting
Recruiting Phase 2 Est. completion 1 April 2027
🇺🇸 US

Who might be able to join this trial: - People who have served in the military (veterans) and are at least 18 years old - People who are able to swallow pills - People who are able to complete all required questionnaires and assessments without assistance or changes to the standard format, and who can attend all requir...

Phase 2: ~30% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT07579143 · Central Arkansas Veterans Healthcare System Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 June 2026
🇺🇸 US

Who might be able to join this trial: - People aged between 18 and 80 years old - People who have a planned appointment with a VA mental health clinician for PTSD or substance use treatment within the next three months - People who screen positive on a specific 6-question questionnaire about moral injury (called the MI...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07604753 · The University of Hong Kong Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 January 2028
Hong Kong

Who might be able to join this trial: - You are 18 years old or older and were selected through a random sampling process from an official housing list - You currently live at the address that was selected through the sampling process - You have lived in Hong Kong for at least six months during the past year - You are...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07610187 · Karolinska Institutet Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 4 May 2027
🇸🇪 SE

Who might be able to join this trial: - You are 18 years old or older - You have experienced sexual violence, and it happened at least 1 month ago - You scored at least 30 on a standard PTSD checklist called the PCL-5 (a questionnaire about trauma-related symptoms) - If you take psychiatric medications, your dose has b...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07632131 · First Affiliated Hospital of Fujian Medical University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 28 February 2027
🇨🇳 CN

Who might be able to join this trial: - People who are 18 years of age or older. - People who are scheduled to have heart surgery using a heart-lung bypass machine, with plans to stay in a cardiac surgery intensive care unit (ICU) for more than 24 hours after the operation. - People who are able to communicate clearly,...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07644338 · Shanghai Mental Health Center Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 May 2027
🇨🇳 CN

**Who might be able to join this trial:** - You are between 18 and 50 years old (male or female) - You have been diagnosed with PTSD according to standard diagnostic guidelines, your symptoms have lasted at least 3 months, and PTSD is your main current diagnosis (having depression or an anxiety disorder alongside PTSD...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07652645 · Arkin Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 September 2028
🇳🇱 NL

**Who might be able to join this trial:** - You are an adult (18 years or older) who has served in the military and is being treated at Sinai Center - You have some knowledge of DBT (Dialectical Behaviour Therapy) - Your main diagnosis is PTSD caused by war-related experiences, confirmed through a specific assessment c...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07658157 · Tel Aviv University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 October 2026
🇮🇱 IL

Who might be able to join this trial: - Adults between the ages of 18 and 70 - People who have been diagnosed with post-traumatic stress disorder (PTSD) - People who experience intrusive symptoms, such as flashbacks or unwanted memories related to a traumatic event Who may not be able to join: - People who have a psyc...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07667309 · The University of Texas Health Science Center at San Antonio Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 30 June 2027
🇺🇸 US

Who might be able to join this trial: - People who are able to give informed consent and follow the instructions required by the study - People who have been randomised into a specific related clinical trial titled "Combining Stellate Ganglion Block with Prolonged Exposure for PTSD: A Randomized Clinical Trial" (NCT058...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07680517 · Ohio State University Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 August 2028
🇺🇸 US

**Who might be able to join this trial:** - You are actively seeking treatment and are currently serving in the military (specifically assigned or aligned with JSOC) - You are 18 years of age or older - You have been diagnosed with PTSD, or have significant PTSD symptoms that almost meet the full diagnostic criteria (c...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07703722 · Khyber Medical University Peshawar Phase 3 · 1 country Recruiting
Recruiting Phase 3 Est. completion 22 October 2027
🇵🇰 PK

**Who might be able to join this trial:** - Adults between the ages of 18 and 60 years old - People who have been diagnosed with Major Depressive Disorder (MDD) based on standard medical criteria (DSM-5) - People whose depression is connected to trauma and who have significant trauma-related symptoms - People whose de...

Phase 3: ~65% of drugs entering this phase reach regulatory approval (industry-wide historical average, not specific to this trial)
NCT07707765 · Barzilai Medical Center Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 31 October 2026
🇮🇱 IL

Who might be able to join this trial: - People who have been discharged from an intensive care unit (ICU) after being treated for sepsis (a serious infection-related illness) - People who are 18 years of age or older Who may not be able to join: - People who are under 18 years of age - People who have not given their...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
NCT07710417 · Laureate Institute for Brain Research, Inc. Early Phase 1 · 1 country Recruiting
Recruiting Early Phase 1 Est. completion 1 December 2026
🇺🇸 US

**Who might be able to join this trial:** - People who have experienced trauma connected to their work, and who either score at or above a certain level on a standardised stress symptom checklist (PCL-5), meet criteria for full or partial PTSD on a clinical interview, OR show evidence of work-related trauma exposure a...

Early Phase 1 studies are small, early exploratory studies that come before the main Phase 1 to 3 testing, so a standard phase success rate does not apply.
NCT07710573 · Community Stress Prevention Center Not Applicable · 1 country Recruiting
Recruiting Not Applicable Est. completion 1 December 2027
🇮🇱 IL

Who might be able to join this trial: - People who are 18 years of age or older - People who have PTSD symptoms with a score between 30 and 60 on a standard PTSD checklist (called the PCL-5) - People who speak Hebrew - People who are able to give their informed agreement to take part in the study - People who are willi...

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Advocacy and support in Australia

Organisations that can offer information, support, or connection for PTSD. Where more than one is listed, they serve different needs or regions, so choose whichever fits your situation.

Phoenix Australia, the National Centre of Excellence in Posttraumatic Mental Health, supports people affected by PTSD.

This is a starting point, not medical advice or an endorsement. Contact details change; search the organisation name to find its current website.