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Bipolar Disorder

Clinical trials recruiting in Australia for Bipolar Disorder, as the public registries list them.

Also called: Manic depression; Manic-depressive illness; Bipolar affective disorder; Bipolar affective psychosis; Bipolar spectrum disorder; Depression, bipolar

Sources: ClinicalTrials.gov, MedlinePlus Checked: 11 October 2026 Not medical advice

At a glance

2 trials recruiting in Australia

2 states or territories with a listed site

0 started recruiting in the last 30 days

274 trials recruiting overseas

11 October 2026 date last checked

Where the trials are

Listed sites in each state and territory. Choose one to show only the trials with a site there, and choose it again to show them all.

Trials for Bipolar Disorder

2 of 2 trials shown.

This Australian count is likely to be on the low side. It counts the trials this site files under this condition; the registry’s own search is broader and also returns closely related conditions, some of which have their own page here. If you are searching widely, check the registry as well — every trial below links to its own record.

  • Recruiting Phase 3

    Phase 3 study for people with Bipolar Disorder

    Where
    • Ramsay Clinic Northside, St Leonards (NSW) — Recruiting
    • Ramsay Clinic New Farm, Brisbane (QLD) — Recruiting
    Who can join Age 18 Years to 65 Years. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.
    Sponsor Bristol-Myers Squibb
    Timeline
    Started 18 July 2025 Today 16 October 2026 Estimated completion 13 June 2028

    NCT06929273 · Checked 11 October 2026

  • Recruiting Phase 3

    Phase 3 study for people with Bipolar Disorder

    Where
    • Ramsay Clinic Northside, St Leonards (NSW) — Recruiting
    • Ramsay Clinic New Farm, Brisbane (QLD) — Recruiting
    Who can join Age 18 Years to 65 Years. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.
    Sponsor Bristol-Myers Squibb
    Timeline
    Started 11 June 2025 Today 16 October 2026 Estimated completion 1 November 2026

    NCT06951698 · Checked 11 October 2026

voxsanity.com.au · trial list from public registries · page built 16 October 2026 · not medical advice

Trials not shown here

Some Australian trials are registered only on the Australian New Zealand Clinical Trials Registry and are not shown here. Search them at Australian Clinical Trials.

Trials overseas

274 trials for this condition are open to new participants outside Australia, as ClinicalTrials.gov listed them on 11 October 2026. Voxsanity does not publish a page for any of them; the searches below reach them at the registry.

These overseas counts are likely too high. They come from the registry’s own search, which expands a condition name to related conditions, so some of the trials counted are for a different disease in the same family.

About Bipolar Disorder

The text below is reproduced exactly as its source published it. It has not been edited, shortened or rewritten.

What is bipolar disorder? Bipolar disorder is a mood disorder that can cause intense mood swings: - Sometimes you may feel extremely "up," elated, irritable, or energized. This is called a manic episode. - Other times you may feel "down," sad, indifferent, or hopeless. This is called a depressive episode. - You may have both manic and depressive symptoms together. This is called a mixed episode. Along with mood swings, bipolar disorder causes changes in behavior, energy levels, and activity levels. Bipolar disorder used to be called other names, including manic depression and manic-depressive disorder. What are the types of bipolar disorder? There are three main types of bipolar disorder: - Bipolar I disorder involves manic episodes that last at least 7 days or manic symptoms so severe that you need immediate hospital care. Depressive episodes are also common. Those often last at least two weeks. This type of bipolar disorder can also involve mixed episodes. - Bipolar II disorder involves depressive episodes. But instead of full-blown manic episodes, there are episodes of hypomania. Hypomania is a less severe version of mania. - Cyclothymic disorder, or cyclothymia, also involves hypomanic and depressive symptoms. But they are not as intense or as long-lasting as hypomanic or depressive episodes. The symptoms usually last for at least two years in adults and for one year in children and teenagers. With any of these types, having four or more episodes of mania or depression in a year is called "rapid cycling." What causes bipolar disorder? The exact cause of bipolar disorder is unknown. Several factors likely play a role in the disorder. They include genetics, brain structure and function, and your environment. Who is at risk for bipolar disorder? You are at higher risk for bipolar disorder if you have a close relative who has it. Going through trauma or stressful life events may raise this risk even more. What are the symptoms of bipolar disorder? The symptoms of bipolar disorder can vary. But they involve mood swings known as mood episodes: - The symptoms of a manic episode can include: - Feeling very up, high, or elated - Feeling jumpy or wired, more active than usual - Having a very short temper or seeming extremely irritable - Having racing thoughts and talking very fast - Needing less sleep - Feeling like you are unusually important, talented, or powerful - Do risky things that show poor judgment, such as eating and drinking too much, spending or giving away a lot of money, or having reckless sex - The symptoms of a depressive episode can include: - Feeling very sad, hopeless, or worthless - Feeling lonely or isolating yourself from others - Talking very slowly, feeling like you have nothing to say, or forgetting a lot - Having little energy - Sleeping too much - Eating too much or too little - Lack of interest in your usual activities and being unable to do even simple things - Thinking about death or suicide - The symptoms of a mixed episode include both manic and depressive symptoms together. For example, you may feel very sad, empty, or hopeless, while at the same time feeling extremely energized. Some people with bipolar disorder may have milder symptoms. For example, you may have hypomania instead of mania. With hypomania, you may feel very good and find that you can get a lot done. You may not feel like anything is wrong. But your family and friends may notice your mood swings and changes in activity levels. They may realize that your behavior is unusual for you. After the hypomania, you might have severe depression. Your mood episodes may last a week or two or sometimes longer. During an episode, symptoms usually occur every day for most of the day. How is bipolar disorder diagnosed? To diagnose bipolar disorder, your health care provider may use many tools: - A physical exam - A medical history, which will include asking about your symptoms, lifetime history, experiences, and family history - Medical tests to rule out other conditions - A mental health evaluation. Your provider may do the evaluation or may refer you to a mental health specialist to get one. What are the treatments for bipolar disorder? Treatment can help many people, including those with the most severe forms of bipolar disorder. The main treatments for bipolar disorder include medicines, psychotherapy, or both: - Medicines can help control the symptoms of bipolar disorder. You may need to try several different medicines to find which one works best for you. Some people need to take more than one medicine. It's important to take your medicine consistently. Don't stop taking it without first talking with your provider. Contact your provider if you have any concerns about side effects from the medicines. - Psychotherapy (talk therapy) can help you recognize and change troubling emotions, thoughts, and behaviors. It can give you and your family support, education, skills, and coping strategies. There are several different types of psychotherapy that may help with bipolar disorder. - Other treatment options include: - Electroconvulsive therapy (ECT), a brain stimulation procedure that can help relieve symptoms. It uses a mild electric current and is done while you are under general anesthesia. ECT is most often used for severe bipolar disorder that is not getting better with other treatments. It may also be used when someone needs a treatment that will work more quickly than medicines. This might be when a person has a high risk of suicide or is catatonic (unresponsive). - Repetitive transcranial magnetic stimulation (rTMS), a brain stimulation procedure that uses magnetic waves to relieve depression. It is not as powerful as ECT, but with rTMS, you don't need general anesthesia. It also has a low risk of negative effects on your memory and thinking. - Light therapy has been shown to be effective for seasonal affective disorder (SAD). Many people with bipolar disorder also find that their depression gets worse during certain seasons, usually in the fall and winter. Light therapy may help with their symptoms. - Healthy lifestyle changes, such as getting regular exercise, having a consistent sleep schedule, and keeping a mood journal, can also help with your symptoms. Bipolar disorder is a lifelong illness. But long-term, ongoing treatment can help manage your symptoms and enable you to live a healthy, successful life. NIH: National Institute of Mental Health

US source; availability in Australia may differ.

Source: MedlinePlus Health Topics (medlineplus.gov), public domain (U.S. National Library of Medicine). Read the full source.

Sources and dates

  • ClinicalTrials.gov – trial records, statuses and site lists
  • MedlinePlus – the About text above, reproduced exactly
  • ClinicalTrials.gov processing date: 22 September 2026.
  • This page last checked by Voxsanity: 11 October 2026.

Voxsanity reformats data from public registries into this layout. It does not edit, interpret or add to what the registry published.

Not medical advice.

Individual trial records are refreshed on a rolling basis rather than all at once, so a record may be up to several weeks old. Each trial page and trial card shows the date its own record was last synced. Where a record has lagged, its status, sites and enrolment can differ from the current registry state in either direction, so check the registry link on the trial page before acting on them.

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