Non-Alcoholic Fatty Liver Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You must be 18 years of age or older.
- You have been diagnosed with, or are suspected to have, a liver condition called NAFLD (a build-up of fat in the liver not caused by alcohol), confirmed by one of the following: a past liver biopsy showing NAFLD; a current or planned liver biopsy for suspected NAFLD supported by blood or scan results; or scan evidence of advanced liver scarring (cirrhosis) with no other known cause, plus at least 2 signs of "metabolic syndrome" such as a large waist size, high blood sugar or diabetes, abnormal cholesterol or fat levels in the blood, or high blood pressure.
- You drink, on average, fewer than 21 units of alcohol per week (if male) or fewer than 14 units per week (if female), and have not had a long history of heavy drinking in the past 5 years.
Who may not be able to join:
- You are unwilling or unable to give your consent to take part in the study.
- You drink more alcohol per week than the limits described above, or have had a sustained period of heavy drinking in the last 5 years.
- You have been diagnosed with Type 1 diabetes.
- You have any other long-term liver condition other than NAFLD.
- You have used certain medications known to cause fat build-up in the liver in the past 12 months (such as long-term steroids, amiodarone, methotrexate, tamoxifen, tetracycline, high-dose oestrogens, or valproic acid) (confirm with trial site).
- You have a medical reason why a liver biopsy would not be safe for you (confirm with trial site).
- You have recently started or changed the dose of certain supplements or medications (such as high-dose Vitamin E, ursodeoxycholic acid, or silymarin) within the past 3 months (confirm with trial site).
- You do not speak English and do not have access to a suitable interpreter, as the study involves collecting information about diet, exercise, and symptoms.
- You do not meet the required inclusion criteria, or the study doctor feels you are not suitable for the trial.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Quentin M Anstee, MBBS, PhD, Newcastle University
Phone: +44(0)191 20 87012
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Detailed Characterisation of the NAFLD Patient Phenotype
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.