Phase 2 Lung Cancer Trial, Recruiting NCT04459065 Sponsor: University of Saskatchewan Condition: Lung Cancer
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Phase 2 Lung Cancer Trial, Recruiting

NCT04459065
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People diagnosed with Stage I or Stage II non-small cell lung cancer that can be removed with surgery.
  • People aged 18 to 80 years old.
  • People whose heart and lung health is strong enough for lung removal surgery, as assessed by the operating surgeon.
  • People with no previous history of cancer.
  • People who have not received any treatment for their cancer before surgery (no pre-surgery chemotherapy or radiation).
  • People who are well enough to carry out most daily activities (based on standard health scoring tools used by doctors).
  • People whose blood test results meet these minimum levels: haemoglobin at or above 90 g/L, white blood cell count above 3 x 10⁹/L, and platelet count at or above 100 x 10⁹/L.
  • People whose kidney function, measured by a blood marker called creatinine, is within an acceptable range.
  • People who are able to give informed consent to participate.

Who may not be able to join:

  • People who have received certain targeted cancer antibody treatments (cetuximab, panitumumab, or necitumumab) within the 60 days before the trial drug would be given.
  • People who are pregnant or currently breastfeeding.
  • People with a known history of allergic reactions to antibodies or products made from a specific type of cell used to manufacture biological medicines (NSO-derived products).
  • People who have had a heart attack, stroke, uncontrolled heart failure, significant liver disease, or unstable chest pain within the 6 months before joining the trial.
  • People currently taking certain heart rhythm medications, specifically Class IA drugs (such as quinidine or procainamide) or Class III drugs (such as dofetilide, amiodarone, or sotalol).
  • People with a history or signs of scarring or inflammation in the lungs (interstitial pneumonitis or pulmonary fibrosis).
  • People considered by the trial investigators to be unsuitable candidates for the study drug for any other reason.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: 306-966-12040

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
University of Saskatchewan
Registry
ClinicalTrials.gov
Start date
1 September 2020
Est. completion
1 September 2026

Where this trial is recruiting

🇨🇦 Canada

Primary endpoints

Phase 1: Optimal dose of IRDye800CW-nimotuzumab for image guided surgery.; Phase 2: Determine the optimal time for IRDye800CW-nimotuzumab infusion for image guided surgery.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov