OCD Trial, Recruiting NCT04480918 Sponsor: Mark Niciu Condition: OCD
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OCD Trial, Recruiting

NCT04480918
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are between 18 and 99 years old
  • You are an English speaker and can understand what the study involves well enough to agree to take part and sign a consent form
  • You have been diagnosed by a provider at the Interventional Psychiatry Service with a major depressive episode related to major depressive disorder, bipolar disorder, or treatment-resistant OCD, and that provider considers you a suitable candidate for treatment through their service

Who may not be able to join:

  • You are under 18 years old
  • Your main psychiatric diagnosis is something other than major depressive disorder or bipolar disorder
  • You have a serious or unstable physical health condition, such as uncontrolled asthma, uncontrolled thyroid problems, active cancer, or significant heart, liver, kidney, lung, nerve, or blood disorders
  • You are currently being held in a psychiatric unit involuntarily
  • You may not be able to take part in the MRI portions of the study if any of the following apply to you:
    • You have an implanted device in your body (such as a pacemaker, heart stent, defibrillator, or nerve stimulator) that is not safe for use in an MRI machine
    • You have metal objects inside your body, such as bullets, shrapnel, or metal fragments
    • You experience significant distress in enclosed spaces (claustrophobia)
    • You have significant hearing loss
    • You are pregnant, breastfeeding, or are able to become pregnant and are not using at least one accepted form of birth control (confirm with trial site)
    • You have a medical condition that may affect brain structure or function, such as high blood pressure or diabetes, even if it is managed with medication

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Mark J Niciu, M.D., Ph. D., University of Iowa Hospitals & Clinics

Phone: 319-384-6521

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Mark Niciu
Registry
ClinicalTrials.gov
Start date
2 November 2020
Est. completion
1 August 2050

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Montgomery-Åsberg Depression Rating Scale (MADRS) Pre-Post Change; Yale-Brown Obsessive Compulsive Scale

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov