Phase 2 Head and Neck Cancer Trial, Recruiting NCT04511078 Sponsor: University of Alabama at Birmingham Condition: Head and Neck Cancer
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Phase 2 Head and Neck Cancer Trial, Recruiting

NCT04511078
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have been diagnosed with squamous cell carcinoma (a type of cancer) in the head or neck area, confirmed by a biopsy
  • Your cancer can be at any stage and in any part of the head or neck, including cases where the cancer has come back or is a new cancer in a different location
  • You are scheduled to have surgery with the goal of curing your cancer as part of your standard treatment
  • You are 18 years of age or older
  • Your doctors expect you to live for more than 12 weeks
  • You are well enough to carry out most daily activities with only minor limitations (confirm with trial site)
  • Your blood, kidney, and liver are working well enough to meet specific test result requirements, including healthy levels of red blood cells, white blood cells, platelets, and kidney function (confirm with trial site for exact values)

Who may not be able to join:

  • You have taken part in another experimental drug study within the last 30 days
  • You have had a heart attack, stroke, or uncontrolled heart failure within the last 6 months
  • You have previously had a serious reaction during an IV infusion of any antibody-based treatment
  • You are currently pregnant or breastfeeding
  • You have an abnormal heart rhythm shown on a heart tracing (ECG) test (confirm with trial site)
  • Your magnesium or potassium blood levels are below normal
  • You are currently taking certain heart rhythm medications, including quinidine, procainamide, dofetilide, amiodarone, or sotalol
  • You have a history of scarring or inflammation in your lungs
  • Your thyroid hormone levels are above a certain limit shown in a blood test (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 5 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Anthony Morlandt, DDS MD, University of Alabama at Birmingham

Phone: (205) 975-6169

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Registry
ClinicalTrials.gov
Start date
2 April 2021
Est. completion
31 December 2030

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Tumor to background ratio of fluorescence (TBR)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 5 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov