Gaucher Disease Trial, Recruiting NCT04528355 Sponsor: Paul Szabolcs Condition: Gaucher Disease
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Gaucher Disease Trial, Recruiting

NCT04528355
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • The patient, their parent, or legal guardian must be willing and able to sign a written consent form.
  • The patient must be between 2 months and 60 years old at the time of signing consent.
  • The patient must have a non-cancerous condition that can be treated with a stem cell transplant, such as:
    • An immune system disorder (for example: Severe Combined Immune Deficiency/SCID, Wiskott-Aldrich Syndrome, Chronic Granulomatous Disease, or similar conditions)
    • A bone marrow disorder present from birth (for example: Congenital Amegakaryocytic Thrombocytopenia or Osteopetrosis)
    • An inherited metabolic disorder (for example: Hurler syndrome, Krabbe Disease, X-linked adrenoleukodystrophy, Gaucher Disease, or similar conditions)
    • An inherited blood disorder (for example: Thalassemia major, Sickle Cell Disease, or Diamond Blackfan Anemia)
    • An inflammatory condition (for example: Crohn's Disease, Rheumatoid Arthritis, or similar conditions)
  • The patient must be receiving a stem cell transplant using cord blood, bone marrow, or blood stem cells, along with a specific reduced-intensity preparation treatment (using a combination of medicines including alemtuzumab, melphalan, thiotepa, fludarabine, and hydroxyurea), as practiced at UPMC Children's Hospital of Pittsburgh.

Who may not be able to join:

  • There are no listed exclusion criteria for this trial.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Paul Szabolcs, MD, UPMC Children's Hospital of Pittsburgh

Phone: 412-692-5427

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Paul Szabolcs
Registry
ClinicalTrials.gov
Start date
20 August 2020
Est. completion
31 December 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

incidence of acute graft versus host disease (GVHD); overall survival after HSCT

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov