Early Phase 1 Interstitial Lung Disease Trial, Recruiting NCT04532346 Sponsor: Children's Hospital of Fudan University Condition: Interstitial Lung Disease
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Early Phase 1 Interstitial Lung Disease Trial, Recruiting

NCT04532346
Recruiting Early Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Children under 18 years old who have been clinically diagnosed with a rare lung condition called chILD (children's interstitial lung disease)
  • People whose chILD has been confirmed through genetic testing, showing a change in one of several specific genes (such as SFTPC, SFTPB, ABCA3, NKX2-1, CSF2RA, CSF2RB, IARS, MARS, COPA, SLC7A7, or LRBA)
  • People whose condition is currently stable, with no major changes to their medications in the past 4 weeks
  • People who have not received a medication called hydroxychloroquine (HCQ) in the past 12 weeks
  • People for whom a signed and dated consent form has been completed — by the child themselves if old enough, and/or by their parent or legal guardian — before any trial procedures begin

Who may not be able to join:

  • People who are currently experiencing a severe, acute infectious flare-up of their condition
  • People with a known allergy or sensitivity to hydroxychloroquine (HCQ) or any of the other ingredients in the trial tablets
  • People who have a confirmed eye condition affecting the retina or macula (the back of the eye)
  • People whose kidneys are not functioning well enough, based on a specific blood filtration measurement taken at the start of the trial (confirm with trial site for the exact thresholds that apply based on the child's age)
  • People who are already taking part in another clinical trial at the same time as this one

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 19 July 2026
Early Phase 1 studies are small, early exploratory studies that come before the main Phase 1 to 3 testing, so a standard phase success rate does not apply.

Contact this trial

Phone: 021-64931913

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Early Phase 1
Sponsor
Children's Hospital of Fudan University
Registry
ClinicalTrials.gov
Start date
1 September 2024
Est. completion
1 October 2026

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Oxygenation status

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 19 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov