Obesity Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are a man or a woman who has not yet gone through menopause
• You are between 18 and 42 years old
• Your body mass index (a measure of body weight relative to height) falls roughly between 23 and 35
• You are willing to drink a special type of water (called deuterium-labeled water) every day for 8 weeks
• You are willing to be randomly placed into one of two groups in the study
• If you are a woman and not using hormonal birth control (such as the pill, ring, injection, or implant), you are willing to use another reliable method to prevent pregnancy for the entire study
• You are willing to follow all study instructions and attend all required appointments
• You agree to keep your exercise and physical activity at the same level throughout the study
• You are willing to have some of your blood stored for possible future research

Who may not be able to join:

• Your weight has gone up or down by about 5% or more in the last 3 months
• You have been diagnosed with Type 1 or Type 2 diabetes, or your fasting blood sugar level is above 110 mg/dL
• Your blood pressure is consistently above 140/90
• You have a serious disease affecting a major organ such as your heart, kidneys, lungs, thyroid, or liver, or you have abnormal liver test results that the study doctor considers significant
• You have reported testing positive for HIV, hepatitis B, or hepatitis C
• You have ever had or currently have an eating disorder
• You regularly take certain medications, including steroids, beta-blockers, antipsychotics, or other medicines known to significantly affect weight (confirm with trial site)
• You regularly take prescription or over-the-counter weight loss medications
• You have been taking antidepressant medication for less than 3 months
• You currently smoke or use tobacco products and cannot stop during the in-person study visits
• You have previously had weight-loss (bariatric) surgery or other surgery for obesity
• You have been diagnosed with cancer in the last 5 years (certain minor skin cancers may be acceptable — confirm with trial site)
• You are currently pregnant, breastfeeding, or planning to become pregnant in the next 6 months
• You have had a full or partial hysterectomy (surgical removal of the uterus)
• You have been diagnosed with polycystic ovary syndrome (PCOS)
• You have been diagnosed with a psychotic condition

Important: Always verify eligibility with the trial site directly before applying.