Phase 3 study
Recruiting Phase 3
This trial at a glance
Where this trial is running
| Site | City | State or country | Status at this site |
|---|---|---|---|
| Royal Prince Alfred Hospital | Camperdown | NSW | Recruiting |
| St Vincent's Hospital Sydney | Darlinghurst | NSW | Active not recruiting |
| St George Hospital | Kogarah | NSW | Recruiting |
| Liverpool Hospital | Liverpool | NSW | Recruiting |
| John Hunter Hospital | New Lambton Heights | NSW | Recruiting |
| Royal North Shore Hospital | Saint Leonards | NSW | Recruiting |
| Westmead Hospital | Westmead | NSW | Recruiting |
| Royal Darwin Hospital | Tiwi | NT | Not yet recruiting |
| Cairns Hospital | Cairns | QLD | Withdrawn |
| Royal Brisbane and Women's Hospital | Herston | QLD | Recruiting |
| Gold Coast University Hospital | Southport | QLD | Recruiting |
| Princess Alexandra Hospital | Woolloongabba | QLD | Recruiting |
| Royal Adelaide Hospital | Adelaide | SA | Recruiting |
| Flinders Medical Centre | Adelaide | SA | Not yet recruiting |
| The Alfred Hospital | Melbourne | VIC | Recruiting |
| Royal Melbourne Hospital | Melbourne | VIC | Recruiting |
| Royal Perth Hospital | Perth | WA | Recruiting |
voxsanity.com.au · trial sites from public registries · registry record synced 11 October 2026 · not medical advice
Who can join
The official eligibility criteria
Registry text, reproduced exactly. These are the words the trial's sponsor published on ClinicalTrials.gov. They have not been edited, shortened or rewritten, and they are written for researchers rather than for patients.
Inclusion Criteria: Patients with trauma admitted to the ICU who:
* Are ≥ 18 to ≤ 75 years of age
* Are \< 24 hours since primary traumatic injury
* Are invasively mechanically ventilated
* Are expected to stay in the ICU ≥ 48 hours
* Have a haemoglobin not exceeding the upper limit of the applicable normal (ULN) reference range in clinical use at the treating institution
* Have informed consent from a legal surrogate according to local law
Exclusion Criteria: Patients will be excluded from the study if any of the following criteria apply:
* GCS = 3 and fixed dilated pupils
* Recent history of DVT, PE or other thromboembolic event (within previous 12 months or receiving concomitant anticoagulant treatment for this indication)
* A chronic hypercoagulable disorder, including known malignancy
* Treatment with EPO in the last 30 days
* First dose of study drug unable to be given within 24 hours of primary injury
* Pregnancy or lactation or 3 months postpartum
* Expected to die imminently (\< 24 hours)
* Known sensitivity to mammalian cell derived products
* Known contraindication to epoetin alfa
* End stage renal failure (receives chronic dialysis)
* Severe pre-existing physical or mental disability or severe co-morbidity that may interfere with the assessment of outcome
* The treating physician believes it is not in the best interest of the patient to be randomised to this trial
Dates on the record
Results, publications and the official record
- No results are posted on the official record yet.
- No publications are listed on the official record yet.
- Official record and contacts on ClinicalTrials.gov – contact details for each site are kept there, and are not copied onto this page.
Sources and dates
- ClinicalTrials.gov – the record this page reformats
- ClinicalTrials.gov processing date: 16 July 2025.
- This page last checked by Voxsanity: 11 October 2026.
Voxsanity reformats data from public registries into this layout. It does not edit, interpret or add to what the registry published.
Not medical advice.
Individual trial records are refreshed on a rolling basis rather than all at once, so a record may be up to several weeks old. Each trial page and trial card shows the date its own record was last synced. Where a record has lagged, its status, sites and enrolment can differ from the current registry state in either direction, so check the registry link on the trial page before acting on them.
Letter for your doctor
A one-page summary of this trial to print or email to your GP. It carries the registry's own record of the trial and its eligibility criteria, and nothing Voxsanity has written about whether it suits you.