OCD Trial, Recruiting NCT04631042 Sponsor: National Institute of Mental Health (NIMH) Condition: OCD
Back to Ocd

OCD Trial, Recruiting

NCT04631042
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are willing to follow all study procedures and are available for the full duration of the study.
  • You are between 6 and 80 years of age.
  • You are able to understand what the study involves and are willing to sign a consent form agreeing to take part.

Who may not be able to join:

  • You have significant difficulty with thinking or understanding that would prevent you from taking part or giving informed consent — for example, a known full-scale IQ under 70 or a history suggesting broad intellectual disabilities.
  • You were born significantly premature (before 32 weeks of pregnancy).
  • You have any known brain abnormality (such as a brain tumor or abnormal brain tissue) or a medical history of conditions that affect the brain's structure, such as epilepsy, stroke, or a head injury that caused loss of consciousness for one hour or more.
  • You have a psychotic disorder, such as schizophrenia or a related condition.
  • You have dementia or another condition that, in the study team's opinion, would make it difficult for you to complete the study.
  • You are currently pregnant.
  • You have any other medical or mental health condition that, in the lead researcher's opinion, could affect the study results or assessments.

For the optional MRI scan only — you may also not be able to participate if:

  • You are unable to have an MRI scan for any reason — for example, if you have metal implants in your body, experience claustrophobia (fear of enclosed spaces), cannot lie flat on your back, are pregnant, or have any other reason that makes MRI unsafe for you (confirm with trial site).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Tonya J White, M.D., National Institute of Mental Health (NIMH)

Phone: (301) 496-5192

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
30 September 2022
Est. completion
31 December 2030

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Glutamate concentration measured using Magnetic Resonance Spectroscopy; Heritability of cortical glutamate (proportion of variance explained by additive genetic factors).

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov