Migraine Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People aged 16 to 65 years who have no known vascular risk factors, such as high blood pressure, high cholesterol, diabetes, atrial fibrillation, smoking, or obesity
- People who have a confirmed hole in the heart called a PFO (patent foramen ovale), with a significant amount of blood flow passing through it in the wrong direction, as measured by a specific ultrasound test
- Stroke group (Phase 1): People who have had a stroke or a mini-stroke (TIA) within the past 6 months, confirmed by a brain MRI scan, with no other explanation found for why it happened
- Migraine group (Phase 2): People who have had migraine headaches for more than one year, with no other explanation found for why they occur
- Control group (Phase 3): People who have been found to have a PFO by chance, with no neurological or other related symptoms
Who may not be able to join:
- People whose stroke, mini-stroke (TIA), or migraines appear to have a cause other than the PFO
- People who have had a stroke or mini-stroke within the past one month
- People who have an enlarged heart or a heart that is not functioning properly
- People who have other structural problems or diseases affecting the heart
- People who have narrowing or disease in the carotid arteries (neck arteries) or the coronary arteries (heart arteries)
- People who have a blood clot in a deep vein (deep vein thrombosis) or in the lungs (pulmonary embolism)
- People who have an implanted cardiac device, such as a pacemaker
- People whose blood has been found to clot too easily (hypercoagulable state)
- People who are allergic to contrast dye used in medical imaging
- People whose heart scan shows a clot, abnormal growth, tumour, or tissue growth inside the heart
- People who have an active heart infection (endocarditis) or another active infection
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: +861088398408
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Adverse Events after evaluation of PFO internal microstructure
Can't join this trial?
Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.