Migraine Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You have been diagnosed with migraine (with or without aura) or chronic migraine that meets standard medical diagnostic guidelines.
- Over a 28-day headache diary, you have between 4 and 28 headache days per month.
- Your migraine-related disability score (called PedMIDAS) is above 4 but below 140, meaning migraines cause at least some disruption to daily life but are not at the most extreme level of disability.
- You are currently taking, or will be on a stable dose throughout the 12-week study of, one or more of these medications or supplements: Vitamin B2, Co-Q10, Magnesium, Vitamin D2 or D3, Depakote, Inderal, Elavil, Topamax, or Periactin.
- You are able to speak English and complete interviews and questionnaires in English.
Who may not be able to join:
- You have had a continuous, non-stop headache for an entire 28-day period.
- You are unable or unwilling to limit use of general pain relievers (such as ibuprofen) to no more than 3 times per week, or migraine-specific medications (such as triptans) to no more than 6 times per month.
- Your PedMIDAS disability score is above 140, suggesting an extreme level of migraine-related disability.
- You are pregnant, or sexually active without using an accepted form of contraception such as barrier or hormonal methods.
- You have a serious psychiatric condition, alcohol or drug dependence, a documented developmental condition (such as autism or cerebral palsy), or any other circumstance that the trial team believes could interfere with safe participation or following the study requirements (confirm with trial site).
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Scott Powers, PhD, Children's Hospital Medical Center, Cincinnati
Phone: 513-636-9739
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Change in number of headache days
Can't join this trial?
Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.