Phase 2 Bladder Cancer Trial, Recruiting NCT04724928 Sponsor: University Hospital, Ghent Condition: Bladder Cancer
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Phase 2 Bladder Cancer Trial, Recruiting

NCT04724928
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with muscle-invasive bladder cancer (a cancer that has grown into the muscle wall of the bladder), confirmed by a tissue sample from a surgical procedure or by scans showing the cancer has reached a certain stage
  • People whose bladder cancer has been staged using chest and abdomen/pelvis scans, showing the cancer is at a certain level of spread within or near the bladder but has not spread to distant parts of the body
  • People aged 18 years or older
  • People who are in reasonably good general health, as measured by a standard medical scale (confirm with trial site)
  • People who are willing to have a specialised full-body scan called an 18F-FDG-PET-CT scan
  • People who are willing to receive either a targeted radiation treatment (for limited spread of disease) or immunotherapy (for more widespread disease), depending on what the PET-CT scan finds
  • People who are willing and able to give signed agreement to participate, following standard research guidelines

Who may not be able to join:

  • People whose scans have already shown that the cancer has spread to distant parts of the body
  • People who are unwilling or unable to have an 18F-FDG-PET-CT scan, or who have a medical reason preventing them from having one
  • People who are unwilling to receive the targeted radiation treatment or immunotherapy that may be recommended based on scan results
  • People who have had previous radiotherapy in a way that would prevent the targeted radiation treatment from being used (confirm with trial site)
  • People who have a medical reason that prevents them from safely receiving radiotherapy, including those with active inflammatory bowel disease
  • People who have a medical reason that prevents them from safely receiving immunotherapy
  • People who have been diagnosed with another type of cancer within the last 5 years that still requires treatment — with the exception of a non-spreading prostate cancer diagnosed at the same time as the bladder cancer, or a type of non-melanoma skin cancer

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Valerie Fonteyne, MD; PhD, UZ Ghent

Phone: +3293323015

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
University Hospital, Ghent
Registry
ClinicalTrials.gov
Start date
29 April 2021
Est. completion
31 December 2029

Where this trial is recruiting

🇧🇪 Belgium

Primary endpoints

Overall survival

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov