Phase 2 Chronic Kidney Disease Trial, Recruiting NCT04741646 Sponsor: University of California, Los Angeles Condition: Chronic Kidney Disease
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Phase 2 Chronic Kidney Disease Trial, Recruiting

NCT04741646
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Children and teenagers between 6 and 18 years old (inclusive)
  • People whose kidneys are working at a reduced level, measured by a specific kidney function test called GFR, falling between 15 and 59 ml/min per 1.73 m² using a formula designed for children
  • People whose blood phosphate level is 5.9 mg/dl or below
  • People whose blood iron storage levels (ferritin below 500 ng/ml and TSAT below 50%) are within the required range
  • People taking growth hormone, certain vitamin D supplements, iron, or red blood cell stimulating medicines, as long as the doses of those treatments have been stable for at least 2 weeks before the screening visit
  • People who are able to swallow tablets
  • People who are able to eat at least two meals a day
  • People who, in the opinion of the trial doctor, are willing and able to follow the study treatment plan and recommendations

Who may not be able to join:

  • People who are currently taking phosphate binder medications
  • People with a known allergy to any ingredient (including non-medical ingredients) in both the study product and the placebo
  • People who have a documented history of intestinal malabsorption, inflammatory bowel disease, or Crohn's Disease
  • People for whom dialysis or a kidney transplant is expected to be needed within the next 6 months
  • People who are currently taking or plan to take medicines that suppress the immune system
  • People who have previously received a solid organ transplant (such as a kidney, liver, or heart)
  • People who received a bone marrow transplant within the two years before the screening visit
  • People who are currently pregnant or breastfeeding, or females who have started their menstrual periods, unless highly effective contraception is being used as specified in the trial protocol (confirm with trial site)
  • People who are already taking part in another interventional clinical trial (participation in observational studies is allowed)
  • People who, in the opinion of the trial doctor, have a history of not following medical treatments as directed
  • People with a condition called cystinosis
  • People with a condition called Fanconi syndrome
  • People with hemochromatosis, or whose blood test results suggest possible hemochromatosis or another condition involving excess iron in the body

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 9 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Isidro B Salusky, MD, University of California, Los Angeles

Phone: 310-7943144

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Registry
ClinicalTrials.gov
Start date
17 June 2022
Est. completion
1 October 2027

Where this trial is recruiting

🇨🇦 Canada 🇺🇸 United States

Primary endpoints

iFGF23 levels; Safety of Ferric Citrate; Tolerability of Ferric Citrate

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 9 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov