Leukaemia Trial, Recruiting NCT04785989 Sponsor: University of Wisconsin, Madison Condition: Leukaemia
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Leukaemia Trial, Recruiting

NCT04785989
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

This trial has three groups. People may be considered for one of the following groups:

Group A (Healthy volunteers):

  • Adults aged 18 or older
  • No previous history of cancer
  • A history of normal blood counts and vital signs on routine check-ups
  • Willing and able to provide informed consent

Group B (Early-stage blood cancer):

  • Adults aged 18 or older
  • A diagnosis of Chronic Lymphocytic Leukaemia (CLL) at an early stage, meaning slightly elevated white blood cells but no enlarged lymph nodes, spleen, or liver, and near-normal red blood cell and platelet counts
  • Has not yet received any treatment for CLL
  • Willing and able to provide informed consent

Group C (More advanced blood cancer):

  • Adults aged 18 or older
  • A diagnosis of CLL that has spread significantly, to the point where bone marrow is affected and blood cell counts are lowered
  • Has not yet received any treatment for CLL
  • Willing and able to undergo a bone marrow aspiration procedure (a sample taken from inside a bone)
  • Willing and able to provide informed consent

Who may not be able to join:

  • People under 18 years of age
  • People who are currently incarcerated
  • People who are currently admitted to a psychiatric facility or living in an institution
  • People with a history of diabetes
  • People who are currently taking medication to lower blood sugar
  • People who follow carbohydrate-restricting diets, such as Atkins, Vegan, or Ketogenic diets
  • Women who are able to become pregnant
  • People who are not able to make their own medical decisions
  • People who are unable to read or write in English
  • People who do not meet the inclusion criteria listed above

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 14 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Christopher Fletcher, MD, School of Medicine and Public Health, University of Wisconsin, Madison

Phone: 800-622-8922

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
13 June 2022
Est. completion
1 October 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Amount of [U-13C]glucose incorporation into metabolites in normal and leukemic lymphocytes: Liquid chromatography-mass spectrometry (LCMS) pharmacokinetic analysis; Amount of [U-13C15N]L-glutamine incorporation into metabolites in normal and leukemic lymphocytes: LCMS pharmacokinetic analysis

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 14 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov