Phase 2 Leukaemia Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People under 18 years of age who have been newly diagnosed with a type of blood cancer called APL (acute promyelocytic leukaemia), confirmed by a specific genetic marker known as the PML/RARα fusion gene
- Cases where a parent or legal guardian has provided written consent for the child to participate
Who may not be able to join:
- People initially suspected of having APL but later found not to have the specific PML/RARα genetic marker — the trial site would withdraw these patients and move them to a different treatment plan
- People with serious liver problems, indicated by certain blood test results being significantly above normal levels (confirm with trial site)
- People with kidney function that is significantly below normal for their age, based on blood test results (confirm with trial site)
- People with significant heart rhythm problems, abnormal heart test (EKG) results, or reduced heart function below certain thresholds (confirm with trial site)
- People with nerve damage or nerve-related conditions (neuropathy)
- People who currently have another active cancer diagnosis
- People with a severe, uncontrolled life-threatening infection
- People who are pregnant or breastfeeding
- People who have already received alternative treatment for APL, either because APL was not initially suspected or because the standard trial medicines were not available at the time
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Fanco Locatelli, Prof, Dept. of Pediatric Hematology Oncology - Bambino Gesù Children's Hospital Rome
Phone: 0039 051 2144667
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Event Free Survival (EFS) probability
Can't join this trial?
Data last synced from ClinicalTrials.gov: 16 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.