Endometrial Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have been diagnosed with a specific type of cervical cancer confirmed by a tissue biopsy — either adenocarcinoma (usual/classic/NOS), squamous cell carcinoma, or adenosquamous carcinoma (including glassy cell).
• People whose cancer is at a specific early stage (FIGO Stage IA2, IB1, or IB2 using 2018 guidelines), with no sign that the cancer has spread to nearby tissues, lymph nodes, or other parts of the body, and whose tumor measures 4 cm or smaller as confirmed by MRI before joining the trial.
• People whose uterus is smaller than 12 cm and whose doctor considers them suitable for the surgical approach used in this trial.
• People who are healthy enough to have surgery, have completed standard pre-surgery check-ups (such as blood tests and a heart tracing), and are willing to be randomly assigned to either open surgery or robotic surgery for removal of the uterus (a radical or simple hysterectomy).
• People aged 18 or older.
• People who are generally active and able to carry out daily activities, as measured by a standard health scale (ECOG performance status of 0 or 1) (confirm with trial site).
• People who have had a negative pregnancy test within 30 days before surgery, if they have not yet gone through menopause.
• People who have read and signed the consent forms allowing their health information to be used for this research.

Who may not be able to join:

• People whose cervical cancer is of a different tissue type, specifically neuroendocrine tumours, or certain other types of adenocarcinoma (such as gastric type, endometrioid, clear cell, serous, signet ring, or minimal deviation).
• People whose cancer is at FIGO Stage IA1, IB3, or Stage II through IV (2018 guidelines).
• People who are unable to have an MRI scan.
• People whose tumour is larger than 4 cm on MRI, or whose MRI or physical examination shows the cancer has clearly spread to nearby tissues in the pelvis or vaginal area.
• People who have signs that the cancer has spread to lymph nodes or other areas, confirmed by imaging or tissue testing.
• People who have previously had radiation therapy to the pelvis or abdomen.
• People who have had another cancer diagnosed within the last 5 years, with the exception of certain common non-melanoma skin cancers.
• People who are unable to remain in specific body positions required during surgery for an extended period (confirm with trial site).
• People who live too far from the trial site or whose circumstances would make regular follow-up visits difficult.
• People living with HIV whose condition is not well managed and whose CD4 count (an immune system measure) is below 500.

Important: Always verify eligibility with the trial site directly before applying.