Non-Alcoholic Fatty Liver Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You are willing and able to give your consent to participate
- You are 18 years old or older at the time of signing consent
- Your Body Mass Index (BMI) is between 23 and 30 at the screening visit
- You have been diagnosed with fatty liver disease (NAFLD), confirmed by a liver biopsy or a specific type of imaging scan (such as an ultrasound, CT scan, or MRI) within the past 6 months
- A special liver fat scan (called H-MRS) done during screening shows that at least 10% of your liver is made up of fat
- Your blood tests at screening show you do not currently have Hepatitis B or Hepatitis C
Who may not be able to join:
- You have drunk heavily for 3 or more months in a row at any point in the last 5 years (more than 20g of alcohol per day for women, or more than 30g per day for men)
- You have another known long-term liver condition, such as alcoholic liver disease, Hepatitis B or C, autoimmune hepatitis, or liver cancer, among others
- You have Type 2 Diabetes that is currently or has previously been treated with insulin or a type of medication called sulfonylureas
- You have taken prescription medications specifically to treat fatty liver disease in the past 6 months (taking Vitamin E is acceptable)
- Your body weight has dropped by more than 10% in the 6 months before screening
- You have been diagnosed with cirrhosis (serious liver scarring) or show signs of it on scans or physical examination
- You have a history of a Child-Pugh score of 7 or higher, which is a measure of serious liver disease (confirm with trial site)
- You have had a liver transplant, or are currently on a waiting list for one
- You are known to be HIV positive
- You have had or are planning weight-loss (bariatric) surgery, are taking prescription medication for weight loss, or are currently enrolled in a formal weight-loss program
- You have a pacemaker, a metal clip in your brain, or another reason you cannot safely have an MRI scan
- You have chronic kidney disease with a kidney function score (eGFR) below 60
- You are pregnant, trying to become pregnant, or are currently breastfeeding (a pregnancy test will be required at screening for women who could become pregnant)
- You have another serious long-term illness that the study doctor believes could make participation unsafe (confirm with trial site)
- You have any other condition that the study doctor believes could make it difficult for you to complete the trial (confirm with trial site)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Kathleen Corey, MD, Massachusetts General Hospital
Phone: 6177265925
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Liver Fat Content
Can't join this trial?
Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.