Phase 1 Sickle Cell Disease Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You have been diagnosed with sickle cell disease (a specific confirmed type, such as HbSS, SC, S/β-thalassemia, SD, SE, or SO) confirmed by a blood test.
• You are 18 years old or older.
• You are able to understand the study information and agree to take part by signing a consent form.
• If you are already taking certain medications for sickle cell disease (such as hydroxyurea, L-glutamine, crizanlizumab, voxelotor, or erythropoietin-stimulating agents), you must have been taking them for at least 12 weeks before joining and plan to continue at the same dose throughout the study.
• You have had at least 2 pain crises (called vaso-occlusive crises) that required a visit to a healthcare setting in the 12 months before joining the study.

Who may not be able to join:

• You currently have an active cancer diagnosis.
• You are currently pregnant or breastfeeding.
• You are on a regular, planned blood transfusion programme for prevention purposes, or you plan to have an exchange transfusion during the study (note: one-off transfusions given in response to a sudden worsening of your condition are allowed).
• You have taken part in another clinical trial involving an experimental treatment within the past 30 days (or longer, depending on the medication used), or you plan to join another experimental drug trial at the same time.

Important: Always verify eligibility with the trial site directly before applying.