OCD Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You are able to give your consent to participate in the study
- You are between 22 and 75 years old
- You have been diagnosed with OCD (Obsessive-Compulsive Disorder)
- You have had OCD for at least 5 years
- Your OCD is rated as severe or extreme (based on a specific symptom scale called the YBOCS, with a score of 28 or higher)
- You have tried at least two SSRI medications (a common type of antidepressant), as well as a medication called clomipramine, and added-on antipsychotic medications, without enough improvement
- You have tried a specific type of talking therapy for OCD (called cognitive behavioral therapy with exposure and response prevention) and it has not helped enough
- You have tried a brain stimulation treatment called TMS for OCD (if it was available to you) and it did not help enough
Who may not be able to join:
- Your main type of OCD involves hoarding as the primary problem
- You have another serious mental health condition, such as a personality disorder, psychosis, bipolar disorder, or a substance misuse problem
- You are pregnant
- Your MRI scan shows something abnormal, or you have a brain or nervous system condition that may require an MRI in the future
- You have a condition affecting memory or thinking ability, such as dementia
- You are considered to be at immediate risk of suicide, or you have ever attempted suicide
- You are unable to attend the required follow-up appointments during the study
- You have a serious health condition that would make surgery more risky, such as a previous stroke, severely high blood pressure, severe diabetes, or a need for blood-thinning medication (other than aspirin)
- You have a known allergy or sensitivity to the materials used in the device being studied, including titanium, polyurethane, silicone, or stainless steel
- You have previously had brain surgery, including a similar type of brain stimulation surgery (deep brain stimulation) or surgery that removes brain tissue
- You may not be eligible if the trial doctor feels that your individual circumstances significantly increase the risks or reduce the likely benefit of the treatment (confirm with trial site)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Andrew M Lee, MD, PhD, University of California, San Francisco
Phone: 415-502-5472
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Change in Yale-Brown Obsessive Compulsive Scale (Y-BOCS) from 12 months to 24 months
Can't join this trial?
Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.