Phase 3 Endometrial Cancer Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who are willing to take part and have signed a consent form agreeing to join the study
• Women aged 18 to 75 years old
• People diagnosed with cervical cancer of a specific cell type: squamous cell carcinoma, adenocarcinoma, or adenosquamous cell carcinoma
• People whose cancer has been staged as IB2 to IVA (using the 2009 FIGO staging system), with cancer found in the pelvic lymph nodes but not in the lymph nodes higher up near the major blood vessels, as confirmed by a PET-CT scan
• People whose health allows them to receive cisplatin chemotherapy
• People with a general health and activity level rated as 0 or 1 on the ECOG scale, meaning they are fully active or have only minor limitations in physical activity (confirm with trial site)
• People whose life expectancy is greater than 6 months
• Women who could become pregnant must have had a negative pregnancy test (blood or urine) within 7 days before joining, and must be willing to use appropriate contraception throughout the trial
• People who, in the opinion of the research team, are able to follow the trial's procedures and requirements

Who may not be able to join:

• People with a severe infection that is not under control
• People who have been diagnosed with another cancer within the past 5 years, or who have another cancer currently requiring treatment
• People who have already received any anti-cancer treatment for their current diagnosis
• People with liver cirrhosis, serious liver disease, chronic kidney problems, or kidney failure
• People with a history of immune system problems, including HIV positive status or other inherited or acquired immune deficiencies
• People who have had a heart attack, serious heart rhythm problems, or moderate-to-severe heart failure (Grade 2 or above on the NYHA scale)
• People who have previously had a procedure to block the pelvic arteries (pelvic artery embolization)
• People who have previously received radiation therapy to the pelvic area for cancer
• People with a history of severe allergic reactions to platinum-based chemotherapy drugs (such as cisplatin)
• People who need to take medications during the treatment period that are known to cause liver or kidney damage (for example, certain tuberculosis medications)
• People who are unable to understand the trial information, are unwilling to cooperate, or refuse to sign the consent form
• People with other health conditions or circumstances that could put them at serious risk or prevent them from completing the study

Important: Always verify eligibility with the trial site directly before applying.