Phase 3 Uveitis Trial, Completed NCT04976777 Sponsor: AbbVie Condition: Uveitis
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Trial results

AI generated results summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

According to the results reported on ClinicalTrials.gov, this trial (NCT04976777) involved 54 people in total. Participants were split into two groups: 36 people received an updated version of a dexamethasone eye implant delivery system (called the Updated DEX PS DDS 0.7 mg), and 18 people received the already-approved version of the same delivery system (Approved DEX PS DDS 0.7 mg). The trial was primarily measuring how many participants in each group experienced at least one unwanted medical event (called an adverse event) during the study period. Nearly all participants finished the study — 35 out of 36 in the updated device group, and all 18 in the approved device group. The reported data shows that in the updated device group, 13 out of 36 participants experienced at least one adverse event. In the approved device group, 7 out of 18 participants experienced at least one adverse event. The trial also set out to measure how well the updated applicator device physically performed when delivering the implant into the eye, but no numerical results for that outcome were reported in the data submitted to ClinicalTrials.gov. These are the results as reported to ClinicalTrials.gov. They are not medical advice — always discuss what they mean for you with your doctor.

These are the results as reported to ClinicalTrials.gov, not medical advice. Verify independently with the trial site and discuss what they mean for you with your doctor.

Phase 3 Uveitis Trial, Completed

NCT04976777
Completed Phase 3

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have swelling in the central part of your eye (called macular edema) caused by a blocked vein in your retina (either a branch or central retinal vein occlusion) or by diabetes.

Who may not be able to join:

  • You have a condition in the eye being studied that means you cannot safely receive the specific slow-release dexamethasone (steroid) implant used in this trial (confirm with trial site).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

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Trial details

Status
Completed
Phase
Phase 3
Sponsor
Registry
ClinicalTrials.gov
Start date
12 October 2021
Est. completion
9 February 2022

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Number of Participants Experiencing at Least One Adverse Events (AEs)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov