Interstitial Lung Disease Trial, Recruiting NCT05086432 Sponsor: McMaster University Condition: Interstitial Lung Disease
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Interstitial Lung Disease Trial, Recruiting

NCT05086432
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are over 18 years old
  • You have signed a written consent form before any study activities begin
  • You have been diagnosed with a specific type of interstitial lung disease (ILD), which includes: idiopathic pulmonary fibrosis (IPF), chronic hypersensitivity pneumonitis-related ILD, connective tissue disease-related ILD, or pneumoconiosis (a lung disease caused by inhaling certain dusts)
  • You have had a daily cough for at least 8 weeks
  • You are able to produce a mucus (sputum) sample when given help to do so through a special breathing procedure

Who may not be able to join:

  • You have been diagnosed with systemic sclerosis-related ILD or sarcoidosis
  • Your cough has a known cause, such as a reaction to a blood pressure medication (ACE inhibitor), uncontrolled acid reflux, an upper airway condition, or a recent viral illness
  • You are currently using inhaled steroid medication
  • You are currently taking oral or systemic steroid medication at a relatively high daily dose (confirm with trial site)
  • You are currently taking long-term antibiotic medication
  • You have reduced airflow in your lungs based on a breathing test result (confirm with trial site)
  • You have a doctor-confirmed diagnosis of asthma
  • You have a history of emphysema (a type of lung damage)
  • You have previously had liver problems or a type of jaundice linked to use of a medication called azithromycin
  • You have moderate to severe liver disease based on a specific medical scoring system (confirm with trial site)
  • You have a known allergy or sensitivity to inhaled steroids or a group of antibiotics called macrolides (which includes azithromycin)
  • A heart test (ECG) done at screening shows an abnormal heart rhythm measurement above a certain level (confirm with trial site)
  • You have a known, untreated infection with a type of bacteria called atypical mycobacteria
  • You have a history of hearing loss, ringing in the ears (tinnitus), or dizziness/balance problems (vertigo)
  • You are taking medications that are likely to reduce coughing, such as morphine, gabapentin, or amitriptyline

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 16 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: 9055221155

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
McMaster University
Registry
ClinicalTrials.gov
Start date
22 May 2025
Est. completion
1 March 2027

Where this trial is recruiting

🇨🇦 Canada

Primary endpoints

Change in hourly cough frequency

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 16 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov