Brain Cancer Trial, Recruiting NCT05086497 Sponsor: Abramson Cancer Center at Penn Medicine Condition: Brain Cancer
Back to Brain Cancer

Brain Cancer Trial, Recruiting

NCT05086497
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 22 years or older
  • People who have been diagnosed with glioblastoma (GBM), confirmed through laboratory testing of tumour tissue
  • People who have already had surgery to remove as much of the tumour as safely possible, followed by a full course of radiation therapy (either a 6-week course or a shorter 3-week course)
  • People with any variation of certain tumour genetic markers (related to MGMT and IDH gene characteristics)
  • People whose blood, liver, and kidney function are at adequate levels (confirm with trial site)
  • People who are willing to use a device called Tumour Treating Fields (TTFields), which delivers low-intensity electrical fields to the tumour area

Who may not be able to join:

  • People whose GBM is located in the lower part of the brain, below a structure called the tentorium (confirm with trial site)
  • People who are pregnant
  • People with serious existing health conditions that would prevent them from safely receiving standard chemotherapy (called temozolomide)
  • People who have an active implanted medical device (such as a pacemaker, defibrillator, deep brain stimulator, spinal cord stimulator, vagus nerve stimulator, or programmable shunt), a skull defect where bone is missing without replacement, or bullet fragments in the body
  • People who have a known sensitivity or allergic reaction to conductive gels, such as those used on ECG stickers or TENS electrode pads
  • People who have significant bleeding in or around the area where the tumour was located, which could affect the quality of brain scans

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Suyash Mohan, MD, PDCC, University of Pennsylvania

Phone: 267-408-0977

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Abramson Cancer Center at Penn Medicine
Registry
ClinicalTrials.gov
Start date
15 January 2023
Est. completion
30 June 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Time to Progression

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov