Phase 1 Endometrial Cancer Trial, Recruiting NCT05103683 Sponsor: TORL Biotherapeutics, LLC Condition: Endometrial Cancer
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Phase 1 Endometrial Cancer Trial, Recruiting

NCT05103683
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have an advanced solid tumor (a cancer that has grown or spread and forms a solid mass, rather than a blood cancer).
  • Your cancer can be measured using standard imaging scans, according to a set of guidelines called RECIST v1.1.
  • You are generally able to carry out daily activities with little or no limitation (confirm with trial site for exact definition).
  • Your organs such as your liver, kidneys, and heart are functioning well enough to meet the trial's requirements (confirm with trial site for exact values).

Who may not be able to join:

  • You are still experiencing significant side effects from a previous cancer treatment that have not yet mostly cleared up (hair loss and certain lab result changes may be exceptions — confirm with trial site).
  • You have received certain cancer treatments — such as chemotherapy, targeted drugs, or biological therapies — too recently before starting this trial (within the last 14 to 28 days, depending on the type of treatment).
  • You have brain metastases (cancer that has spread to the brain) that are getting worse or causing symptoms.
  • You have a serious medical condition that is not well controlled, or you have an active infection that is not under control.
  • You have a significant history of heart disease.
  • You have a history of certain blood or bone marrow disorders called myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML).
  • You have been diagnosed with another type of cancer within the past 3 years, with some exceptions such as certain treated skin cancers, early-stage breast cancer (DCIS), or low-risk prostate cancer (confirm with trial site for your specific situation).
  • You are currently pregnant or breastfeeding.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 2 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Sponsor
TORL Biotherapeutics, LLC
Registry
ClinicalTrials.gov
Start date
17 November 2021
Est. completion
31 August 2026

Where this trial is recruiting

🇰🇷 South Korea 🇺🇸 United States

Primary endpoints

Incidence and severity of adverse events and serious adverse events; Maximum Tolerated Dose (MTD); Recommended Phase 2 Dose (RP2D)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 2 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov