Phase 2 Obesity Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• Your kidneys are working at a reduced but not severely low level — specifically, a kidney function score (eGFR) between 20 and less than 60 (confirm with trial site if unsure of your score)
• You are physically able to do resistance/strength training exercises
• You have access to a smartphone (Android or Apple), Kindle, desktop, or laptop computer with internet or mobile data

Who may not be able to join:

• You have Type 1 Diabetes
• You have a history of a condition where the stomach empties too slowly (gastroparesis) or the intestines stop moving (paralytic ileus)
• You are already very physically active — specifically, spending 25 minutes or less per hour sitting still, as measured by a movement-tracking device
• You have a history of pancreas inflammation (pancreatitis), or a personal or family history of certain rare hormonal cancers (multiple endocrine neoplasia type 2 or familial medullary thyroid carcinoma), as these may make one of the study medications unsafe for you
• You have had weight-loss (bariatric) surgery in the past
• You have a serious medical condition that may limit your life expectancy to less than one year
• You are expected to start dialysis or receive a kidney transplant within the next 6 months
• The study team believes there are factors that would make it hard for you to stick with the study program
• You are currently pregnant or incarcerated
• You are currently taking part in another clinical trial involving a drug or medical device
• You are not able to give informed consent to participate
• You have been hospitalised or had a major medical procedure in the last 60 days
• You have a known or suspected allergy to a type of medical adhesive film called Tegaderm
• You have used a type of medication called a GLP-1 receptor agonist (such as certain diabetes or weight-loss injections) within the past 30 days
• You have been diagnosed with the most severe level of heart failure (Class IV on the NYHA scale)
• You use supplemental (extra) oxygen during the daytime
• You have cancer that has spread to other parts of the body (metastatic cancer)
• You currently use a mobility aid (such as a cane, walker, or wheelchair)
• Someone in your household is already enrolled in this study

Important: Always verify eligibility with the trial site directly before applying.