Phase 3 Transverse Myelitis Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• Children between 2 and 11 years old (inclusive) at the time of screening
• Children who weigh at least 10 kg (approximately 22 pounds) at the time of screening
• Girls who have started their periods must agree to either avoid sexual intercourse or use reliable birth control during the trial
• Diagnosed with a condition called NMOSD (a disease that affects the spinal cord and optic nerves) with a specific positive blood marker called AQP4 antibody, based on recognised medical criteria
• Has had at least one recorded episode (attack) of the condition in the year before screening, including a first-ever attack
• Neurological condition has been stable for at least 30 days before both the screening visit and the start of the trial
• Disability level falls within a specific range on a standard scale (score 0 to 6.5) (confirm with trial site)
• If already taking an immune-suppressing medication and planning to continue it, the dose must have been unchanged for at least 4 weeks before the trial starts

Who may not be able to join:

• Girls or women who are pregnant or currently breastfeeding
• Shows signs of another condition that looks similar to NMOSD but is a different disease affecting the nervous system
• Has an active or recurring infection (bacterial, viral, fungal, or other) at the start of the trial
• Has evidence of long-term active hepatitis B or hepatitis C (liver infections)
• Has untreated tuberculosis (TB), whether hidden (latent) or active
• Has received a live or live-attenuated vaccine (a type of vaccine using a weakened live virus) within 6 weeks before the trial starts
• Has a history of a severe allergic reaction to a biologic medicine (a type of medication made from biological sources)

Important: Always verify eligibility with the trial site directly before applying.