Obesity Trial, Recruiting NCT05216042 Sponsor: University of Alabama at Birmingham Condition: Obesity
Back to Obesity

Obesity Trial, Recruiting

NCT05216042
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults aged 18 or older (the trial aims to enrol equal numbers of men and women)
  • People who agree to provide a genetic material sample (such as a blood or saliva sample for DNA testing)
  • People who are willing to follow all the requirements of the study protocol throughout the trial

Who may not be able to join:

  • People under the age of 18 at the time of the screening visit
  • People with a BMI (a measure of body weight relative to height) above 45
  • People with a blood pressure reading higher than 140/90 mmHg
  • People who are currently taking more than two medications to control blood pressure
  • People who have been diagnosed with diabetes, have a fasting blood sugar level above 126 mg/dl, have an HbA1C result of 6.5% or higher, or have previously taken diabetes medication
  • People with a past or current history of heart or blood vessel conditions, including stroke, seizures, heart attack, heart failure, mini-strokes (TIA), chest pain (angina), or irregular heartbeat
  • Women who are pregnant, breastfeeding, or who could become pregnant and are not using an acceptable form of birth control (including abstinence) during the study
  • People whose kidneys are not filtering blood efficiently enough, or who have a certain level of protein in their urine that may indicate kidney stress (confirm with trial site for exact values)
  • People with liver enzyme levels (AST and ALT) more than three times the accepted upper normal range
  • People with anaemia — defined as a low red blood cell level below a certain threshold for both men and women (confirm with trial site)
  • People who are unable to exercise on a treadmill

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Pankaj Arora, MD, FAHA, University of Alabama at Birmingham

Phone: 205-934-7173

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
1 April 2022
Est. completion
30 September 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Change in MRproANP levels following a standardized oral glucose challenge between the high genotype group and low genotype group.; Change in Exercise Energy Expenditure between the high genotype and low genotype group.; Change in miR-425 levels following a standardized oral glucose challenge in those with low ANP genotype.; Change in miR-425 levels following a standardized exercise challenge in those with low ANP genotype.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov