Muscular Dystrophy Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• The child must be between newborn age and 3 years and 11 months old at the time of enrollment.
• The child must have been diagnosed with Congenital Myotonic Dystrophy (CDM), meaning they showed symptoms of myotonic dystrophy as a newborn (within the first 30 days of life) — such as poor muscle tone, difficulty feeding, or breathing problems — that required a hospital stay of more than 72 hours.
• The diagnosis must be confirmed by a genetic test showing a specific gene change (an expanded CTG repeat in the DMPK gene) in either the child or the mother, with the child having more than 200 repeats if tested.
• The child's parent or legal guardian must be willing and able to sign a consent form and follow the study procedures.

Who may not be able to join:

• The child has another serious illness (not related to myotonic dystrophy) that could affect their ability to participate or affect the study results, in the opinion of the study doctor.
• The child has experienced a significant injury within the past month.
• The child has metal implants or internal medical devices in their body (this specifically affects one part of the study involving a bone density scan called a DEXA scan — confirm with trial site).
• The child has a history of a bleeding disorder or has a very low platelet count (below 50,000), which affects blood clotting.
• The child has previously had a reaction to local anesthetic (numbing medication used on the skin or a small area of the body).

Important: Always verify eligibility with the trial site directly before applying.