Long COVID Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are between 18 and 74 years old
• You had COVID-19 that was confirmed by a PCR test (nose/throat swab or lung sample)
• You have a specific genetic trait related to how your body responds to a imaging substance called [18F]-DPA-714 (this will be checked through genetic testing)
• You were admitted to intensive care with severe breathing problems due to COVID-19, and needed a breathing machine and heavy sedation for at least 24 hours
• You are still alive at least 24 months after leaving intensive care
• You are willing and able to sign a consent form agreeing to take part
• You are covered by the French national social security system (not the State Medical Aid scheme)
• Depending on which group you are placed in: you either received a medication called dexmedetomidine for at least 24 hours during your intensive care stay, or you did not receive this medication at all during your intensive care stay

Who may not be able to join:

• You are legally protected, under guardianship, or under court-appointed supervision
• You are pregnant or breastfeeding
• You have a medical reason why you cannot have a PET scan or MRI scan
• Your kidneys are not working well enough (confirm with trial site)
• You have a medical reason why you cannot receive the imaging substance [18F]-DPA-714 used in the study (confirm with trial site)
• When you were first admitted to intensive care, you already had a serious neurological condition such as a stroke, a severe head injury, or dementia that affected your ability to live independently

Important: Always verify eligibility with the trial site directly before applying.