Phase 2 Endometrial Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You have agreed to take part and signed a consent form
• You have been diagnosed with early-stage endometrial cancer (a specific low-risk type called endometrioid, grade 1, that has not grown into the muscle wall of the uterus), confirmed through a biopsy or similar procedure
• Scans (such as MRI, CT, or ultrasound) show no signs that the cancer has spread into the uterus muscle wall or to other parts of the body
• You strongly wish to keep your uterus and/or ability to have children
• You are willing and able to attend regular follow-up appointments at the Obstetrics and Gynecology Hospital of Fudan University

Who may not be able to join:

• Test results suggest the cancer has grown deeper into the uterus wall or spread outside the uterus
• Your endometrial cancer has come back after previous treatment
• You have a serious illness or significantly reduced liver or kidney function
• You have a different type of endometrial cancer, another cancer of the reproductive system, breast cancer, or another type of cancer that is affected by hormones and cannot be treated with progesterone
• Your condition requires surgical removal of the uterus or a treatment other than medication
• You are known or suspected to be pregnant
• You have a medical reason why you cannot take the medications used in this trial (Medroxyprogesterone Acetate, Megestrol Acetate, Triptorelin Acetate, or Letrozole) (confirm with trial site)
• You have had any hormone-based treatment in the 3 months before joining the trial
• You have had a serious condition such as a stroke or heart attack, or have a history of blood clots
• You smoke more than 15 cigarettes per day

Important: Always verify eligibility with the trial site directly before applying.