Rare Disease Trial, Recruiting NCT05259605 Sponsor: European Organisation for Research and Treatment of Cancer - EORTC Condition: Rare Disease
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Rare Disease Trial, Recruiting

NCT05259605
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are at or above the legal age of consent in your country
  • You have been newly diagnosed or have a returning (recurrent) primary brain tumour that falls into one of 17 specific tumour types being studied in this trial
  • A stored tissue sample from your brain tumour surgery is available at the trial site (a sample from your first surgery is preferred, but a sample from surgery for a recurrence may also be accepted — except for one specific group in the trial, called Cohort 16, where only tissue from the first surgery is accepted)
  • Brain scan images (MRI or CT) taken at the time of your original diagnosis are available
  • You are willing and able to give your consent to take part

For deceased patients (where a loved one's data may be used):

  • The patient previously agreed during their lifetime to allow their data, tissue, or scans to be used for research, OR a relative has given consent for this use, OR there is a legal basis that covers situations where getting consent is not possible or would cause undue difficulty
  • There is no record that the patient ever objected to their data or samples being used for research
  • An ethics committee has been notified about the use of the data, tissue, or scans
  • Any additional legal requirements in the relevant country have been met

Who may not be able to join:

  • Anyone who does not have a stored tumour tissue sample available at the trial site
  • Anyone whose brain tumour type does not fall within the 17 specific groups being studied (confirm with trial site)
  • Deceased patients whose data or samples cannot meet the legal and ethical requirements listed above

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Michael Weller, EORTC Study Coordinator

Phone: +32 2 774 1611

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
European Organisation for Research and Treatment of Cancer - EORTC
Registry
ClinicalTrials.gov
Start date
21 March 2023
Est. completion
30 December 2027

Where this trial is recruiting

🇦🇹 Austria 🇧🇪 Belgium 🇫🇷 France 🇩🇪 Germany 🇬🇷 Greece 🇮🇹 Italy 🇳🇱 Netherlands 🇳🇴 Norway 🇵🇹 Portugal 🇪🇸 Spain 🇨🇭 Switzerland 🇬🇧 United Kingdom

Primary endpoints

Best overall and objective response; Progression free survival; Overall Survival; Patient and Disease Characteristics

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov