Phase 2 Leukaemia Trial, Recruiting NCT05272293 Sponsor: Belarusian Research Center for Pediatric Oncology, Hematology and Immunology Condition: Leukaemia
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Phase 2 Leukaemia Trial, Recruiting

NCT05272293
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

Patients:

  • People diagnosed with high-risk acute myeloid leukaemia (AML) that is newly diagnosed
  • People with AML that has not responded to initial treatment
  • People with AML that has come back after previous treatment
  • People who are functioning reasonably well in daily life, as measured by a standard health scoring system (a score of 70 or above on the Karnofsky or Lansky scale — confirm with trial site what this means for your situation)
  • People who have given written agreement to take part in the trial

Donors (a family member providing cells):

  • A family member who is a "half-match" (haploidentical) donor
  • A donor who meets standard medical criteria for donating cells through a collection process called apheresis
  • A donor who has given written agreement to take part

Who may not be able to join:

Patients:

  • People who have an infection that is not currently under control
  • People with serious liver problems, based on specific blood test results being five times or more above the normal range for their age
  • People who test positive for HIV

Donors:

  • People who are pregnant
  • People who test positive for HIV, hepatitis B, or hepatitis C

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 9 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Olga Aleinikova, MD, Prof, Belarussian Research Center for Pediatric Oncology, Hematology and Immunology

Phone: +375296341853

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Belarusian Research Center for Pediatric Oncology, Hematology and Immunology
Registry
ClinicalTrials.gov
Start date
1 November 2021
Est. completion
1 December 2025

Where this trial is recruiting

Belarus

Primary endpoints

Objective Response Rate (ORR) (PR+ MLFS+CRi +CR); Leukemia-free survival (LFS); Overall survival (OS)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 9 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov