Cystic Fibrosis Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have been diagnosed with cystic fibrosis (CF) and have at least one copy of a specific gene change called F508del.
• People whose doctor has planned to start them on the medication Trikafta within 30 days of joining the study.
• People aged 19 years or older.
• People whose condition is considered stable according to their treating doctor.
• People whose lung function test result (measuring how much air can be breathed out in one second) is below 90% of what would normally be expected for someone of their age and size.
• People whose body weight falls within a moderate range — not too low or too high (confirm with trial site for exact values).
• People who are non-smokers, or past smokers with a relatively limited smoking history (less than the equivalent of one pack per day for 20 years).
• People who are able to read and understand English.
• People who have received at least two doses of a COVID-19 vaccine.

Who may not be able to join:

• People who have another illness, separate from CF, that significantly causes breathlessness or limits their ability to exercise.
• People who have a long-term airway infection with certain specific bacteria that have infection control implications, such as Mycobacterium abscessus or Burkholderia cepacia complex (confirm with trial site for the full list).
• People for whom exercise testing would be medically unsafe or not recommended.
• People who require extra oxygen, or whose oxygen levels drop very low during exercise.
• People who have had a collapsed lung (pneumothorax) in the past four weeks.
• People who have had an organ transplant.

Important: Always verify eligibility with the trial site directly before applying.