Melanoma Trial, Recruiting NCT05307289 Sponsor: Centre Hospitalier Universitaire de Nice Condition: Melanoma
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Melanoma Trial, Recruiting

NCT05307289
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are 18 years of age or older (male or female)
  • You have been diagnosed with advanced melanoma (skin cancer) that either cannot be surgically removed (Stage III) or has spread to other parts of the body (Stage IV), including cases where the original source of the melanoma is unknown
  • You have not yet received any treatment for your advanced or metastatic melanoma
  • You are about to start immunotherapy as your treatment
  • Your general health and ability to carry out daily activities is good or only mildly limited (confirm with trial site)
  • Your melanoma has been tested for a gene change called BRAF (any result is acceptable)
  • If you are a woman who could become pregnant, you must be willing to use effective contraception during the study
  • You are covered by a social security or health insurance plan (confirm with trial site)
  • You are willing and able to sign a consent form agreeing to take part

Who may not be able to join:

  • You are currently pregnant or breastfeeding
  • Your melanoma started in the eye or in mucous membranes (such as inside the mouth or nose), or your melanoma has spread from the eye
  • Your advanced melanoma is being treated with targeted therapy drugs rather than immunotherapy
  • You have certain health conditions that make starting immunotherapy unsafe, such as HIV, hepatitis B or C, an active autoimmune disease (for example, Crohn's disease, ulcerative colitis, or vasculitis), or a nerve condition such as Guillain-Barré syndrome
  • You are a minor, or an adult who is under legal guardianship, court protection, or who does not have full personal freedom (confirm with trial site)
  • You have a history of serious psychiatric illness or addiction that could affect your ability to consent or follow the study procedures
  • You have any other health condition that the lead doctor feels could affect the study results or put you at risk

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Montaudie Henri, CHU de Nice, Service de Dermatologie

Phone: +33492036488

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
25 May 2022
Est. completion
25 May 2028

Where this trial is recruiting

🇫🇷 France

Primary endpoints

Change from baseline pyrimidine metabolism at 4 years

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov