Phase 3 Endometrial Cancer Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who have been diagnosed through a uteroscopy procedure with either a pre-cancerous thickening of the uterine lining (endometrial atypical hyperplasia) or a very early-stage, low-grade uterine cancer that has not grown into the uterine muscle wall
- People with a body mass index (BMI) below 30 kg/m²
- People whose scans (MRI, CT, or ultrasound) show no signs that the condition has spread outside the uterus
- People who are currently being treated with a hormone medicine called progestin, through one of these approaches: megestrol acetate at a certain dose (with or without a hormonal coil), medroxyprogesterone acetate at a certain dose (with or without a hormonal coil), or a hormonal coil (LNG-IUS) on its own
- People whose condition has not responded well enough to progestin treatment — either remaining stable after 7 months of treatment, or not achieving full remission after 10 months
- People who wish to preserve their ability to have children or to keep their uterus
- People who are able to attend follow-up appointments and comply with additional treatments as required by the trial
Who may not be able to join:
- People with serious other medical conditions or significantly reduced liver or kidney function
- People whose cancer has been confirmed to have grown into the uterine muscle wall or spread beyond the uterus
- People with other types of uterine cancer or other cancers of the reproductive system
- People with breast cancer or other cancers or conditions that are affected by hormones, which may prevent the use of certain trial medications (confirm with trial site)
- People who strongly prefer to have their uterus surgically removed or to pursue a different type of treatment
- People who are known or suspected to be pregnant
- People with a serious acute condition such as a recent stroke or heart attack, or a history of blood clot disorders
- People who smoke more than 15 cigarettes per day
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: 8602133189900
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Complete response rates within 28 weeks of treatment
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.