Phase 2 Bladder Cancer Trial, Recruiting NCT05327647 Sponsor: CHU de Quebec-Universite Laval Condition: Bladder Cancer
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Phase 2 Bladder Cancer Trial, Recruiting

NCT05327647
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are male and 18 years of age or older
  • You have been diagnosed with a type of bladder cancer (non-muscle invasive urothelial carcinoma) confirmed by a tissue sample test
  • Your urologist has recommended that you receive a course of BCG treatment directly into the bladder
  • You may have received certain chemotherapy drugs (gemcitabine, epirubicin, or mitomycin C) placed directly into the bladder immediately after your surgery
  • If your partner could become pregnant, you must agree to use 2 acceptable forms of birth control during the study and for at least 3 months after stopping the study drug

Who may not be able to join:

  • You have received a full course of BCG bladder treatment at any point in the last 5 years
  • You have had a heart attack or been admitted to hospital for heart failure in the past 12 months, or you currently have an unstable heart condition
  • You have high blood pressure that has not been controlled by medication, specifically a top blood pressure reading above 160 on two separate occasions
  • You have a history of liver disease and your liver-related blood test results are more than twice the normal upper limit
  • You have been diagnosed with low testosterone levels, are taking testosterone replacement therapy, or have prostate cancer or another condition being treated with hormonal therapy (confirm with trial site)
  • You are currently receiving treatment for another cancer, or have cancer treatment planned soon, that may affect your survival or your bladder cancer treatment plan
  • You have taken an experimental or investigational drug within 2 weeks before joining the study
  • You are currently taking or planning to take warfarin (also known as coumadin), a blood-thinning medication

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Paul Toren, MD,PhD,FRCSC, CHU de Québec-Université Laval

Phone: 418-525-4444

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
CHU de Quebec-Universite Laval
Registry
ClinicalTrials.gov
Start date
23 June 2022
Est. completion
1 September 2026

Where this trial is recruiting

🇨🇦 Canada

Primary endpoints

Rate of bladder tumour recurrence

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov