Brain Cancer Trial, Recruiting NCT05342454 Sponsor: M.D. Anderson Cancer Center Condition: Brain Cancer
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Brain Cancer Trial, Recruiting

NCT05342454
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

Prospective (forward-looking) part of the study:

  • People aged 18 or older
  • People who are scheduled to have surgery to remove a brain tumor
  • People for whom a pre-surgery brain scan using fMRI (a type of imaging that shows brain activity) is already planned as part of their standard care
  • People for whom a procedure called direct cortical stimulation — where the surgeon gently stimulates areas of the brain during surgery to map important functions — is already planned as part of their standard care

Retrospective (historical records) part of the study:

  • People aged 18 or older whose past pre-surgery fMRI brain scans are held at MD Anderson Cancer Center (from May 2004 onwards)
  • People whose past fMRI records included at least one scan where the person performed a task during the scan

Who may not be able to join:

Prospective part:

  • People who are not able to give informed consent to participate
  • People who are not able to have an MRI scan
  • People whose planned scans involve speech tasks only, and who a clinical neuropsychologist has assessed as being unable to complete any of those speech tasks

Retrospective part:

  • People whose past fMRI scans were too affected by head movement during scanning (moving more than 2 mm or rotating more than 2 degrees) to be usable
  • People whose past scans involved speech tasks only, and who a clinical neuropsychologist assessed as unable to complete any of those speech tasks

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Ho-Ling Liu, PhD, M.D. Anderson Cancer Center

Phone: (713) 563-7383

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
23 May 2022
Est. completion
30 November 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Validate resting-state fMRI (rs-fMRI) mapping of language and motor (hand and tongue) areas obtained by using the software developed in this research.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov