Phase 2 Chronic Kidney Disease Trial, Recruiting NCT05359263 Sponsor: Tor Biering-Sørensen Condition: Chronic Kidney Disease
Back to Chronic Kidney Disease

Phase 2 Chronic Kidney Disease Trial, Recruiting

NCT05359263
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 18 or older
  • People who have chronic kidney disease (CKD) with reduced kidney function, measured by a specific kidney test result falling within a certain range, or a moderately reduced kidney function with significant protein in the urine (confirm exact values with trial site)
  • People already taking a blood pressure/kidney-protecting medication (ACE inhibitor or ARB) at the appropriate dose for at least 4 weeks before joining, if that medication is medically suitable for them
  • People with type 2 diabetes who have been on a stable diabetes medication regimen for more than 30 days before their screening appointment
  • Female patients who are either past menopause (for at least 1 year), have had a surgical procedure that prevents pregnancy, or are using an approved form of contraception throughout the study and for 30 days after it ends
  • People who are able to understand and read Danish
  • People who have signed a consent form agreeing to participate

Who may not be able to join:

  • People who have type 1 diabetes
  • People with type 2 diabetes who have a history of a serious complication called diabetic ketoacidosis
  • People who are currently receiving dialysis (kidney replacement treatment)
  • People who have previously had an organ transplant
  • People who have taken an SGLT2 inhibitor medication within the 8 weeks before enrolling
  • People with a known allergy or sensitivity to SGLT2 inhibitors or any ingredients in the placebo
  • People who have had a heart attack, unstable chest pain, stroke, or mini-stroke within 12 weeks before enrolling
  • People who have had a heart procedure (such as a stent, bypass surgery) or a heart valve repair or replacement within 12 weeks before enrolling
  • People with a serious non-kidney, non-heart medical condition that a doctor judges may limit life expectancy to less than 2 years
  • People with significant liver problems, based on specific blood test results at the time of enrolment (confirm details with trial site)
  • People with known blood-borne illnesses such as Hepatitis A, B, C, D, or E, HIV, Ebola, or Lassa fever
  • Female patients who are pregnant, breastfeeding, or planning to become pregnant during the study or within 6 months after it ends
  • People who have taken part in another clinical trial involving an investigational treatment within the last month before enrolling
  • People who are unable to follow the study instructions, attend follow-up appointments, or complete the study for any reason

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Tor Biering-Sørensen, Research Director

Phone: +4531360232

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Tor Biering-Sørensen
Registry
ClinicalTrials.gov
Start date
8 June 2022
Est. completion
18 February 2025

Where this trial is recruiting

🇩🇰 Denmark

Primary endpoints

Change in LV mass index assessed by echocardiography at 6 months

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov