PTSD Trial, Recruiting NCT05368987 Sponsor: The University of Texas Health Science Center, Houston Condition: PTSD
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PTSD Trial, Recruiting

NCT05368987
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are willing and able to give their informed consent to participate.
  • People who have a current diagnosis of PTSD (for the PTSD group).
  • People who have no current or past psychiatric disorders (for the healthy volunteer comparison group).

Who may not be able to join:

  • People who have ever had a seizure, a significant head injury, or a significant neurological condition (such as a tic disorder).
  • People who have a history of serious psychiatric disorders.
  • People who are currently experiencing significant thoughts of suicide, have had a suicide plan or attempt in the past 6 months, or engage in self-harming behaviour that involves suicidal intent, requires medical attention, or happens daily.
  • People who have used antipsychotic medications within the past year.
  • People who are currently using substances (confirm with trial site for specific details).
  • People who are pregnant (this will be checked with a urine test).
  • People who have metal implants or devices in their body that would make MRI scanning unsafe.
  • People who are currently taking medications that lower the threshold for seizures, such as antipsychotics, high-dose theophylline, or stimulants like methylphenidate. People taking bupropion may be excluded unless they have been on a stable dose for at least 3 months and are taking no more than 300 mg per day.
  • People who have implanted devices in their head (such as shunts or cochlear implants) or metal in their head (not including dental implants).
  • People who are considered at high risk of a strong negative emotional or behavioural reaction, or who are unable to understand the study procedures or the consent process.
  • People in the healthy volunteer group who have any current psychiatric diagnosis.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 22 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Mohammed Milad, PhD, The University of Texas Health Science Center at Houston (UTHealth Houston)

Phone: 713-486-2754

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
1 February 2022
Est. completion
30 September 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Skin Conductance Response (SCR); Skin Conductance Response (SCR); Functional MRI (fMRI) blood-oxygen-level-dependent (BOLD) responses; Functional MRI (fMRI) blood-oxygen-level-dependent (BOLD) responses

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov