Early Phase 1 Brain Cancer Trial, Recruiting NCT05380349 Sponsor: Swedish Medical Center Condition: Brain Cancer
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Early Phase 1 Brain Cancer Trial, Recruiting

NCT05380349
Recruiting Early Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have been diagnosed with a type of brain tumor called Glioblastoma (GBM, WHO grade 4), confirmed by a tissue sample (biopsy or surgery)
  • You are 18 years of age or older
  • Your doctors expect you to live for more than 6 months
  • Your tumor can be reached by surgery, and the surgical team plans to remove all or most of it
  • You are considered reasonably functional in daily life, as measured by a standard medical rating scale (confirm with trial site)
  • You have not previously received any cancer treatment through medication (such as chemotherapy)
  • You have tested negative for HIV, Hepatitis B, and Hepatitis C
  • Your blood test results meet certain minimum requirements, including healthy enough levels of red blood cells, white blood cells, platelets, kidney function, and liver function (confirm with trial site for specific values)

Who may not be able to join:

  • Your cancer has spread to other parts of the body beyond the original tumor
  • You have other diseases or conditions that could hide side effects or seriously affect how your body processes the trial medication
  • You have another serious ongoing medical illness
  • You have high blood pressure that is not well controlled with treatment
  • You have had a heart attack or severe chest pain (unstable angina) within the past 6 months
  • You have had a stroke or a mini-stroke (transient ischemic attack) within the past 6 months

⚠️ Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 21 July 2026
Early Phase 1 studies are small, early exploratory studies that come before the main Phase 1 to 3 testing, so a standard phase success rate does not apply.

Contact this trial

Principal Investigator: Charles S Cobbs, Ivy Center for Advanced Brain Tumor Treatment

Phone: 206-320-2300

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Early Phase 1
Sponsor
Swedish Medical Center
Registry
ClinicalTrials.gov
Start date
19 April 2024
Est. completion
1 December 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

determine safety of CSC/HTS-based combination drug therapy

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov