Muscular Dystrophy Trial, Recruiting NCT05394506 Sponsor: Institut National de la Santé Et de la Recherche Médicale, France Condition: Muscular Dystrophy
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Muscular Dystrophy Trial, Recruiting

NCT05394506
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have a mutation in the LMNA gene that has led to a diagnosis of a condition called "laminopathy" that affects the muscles
  • You have symptoms of the disease, such as muscle weakness or tendon tightening, with or without breathing or heart problems
  • You are either the first person in your family diagnosed with this condition, or you are a family member related to that person
  • You are able to safely have a small sample of muscle or skin taken (a biopsy) — meaning you do not have allergies to latex, antiseptics, local anesthetics, or adhesive dressings, you are not currently taking blood-thinning medications, and you do not have a bleeding disorder
  • You (if an adult) or both of your child's legal guardians (if the patient is a minor) are willing and able to sign a consent form agreeing to take part
  • You are covered by the French social security system, French Universal Medical Coverage (CMU), or an equivalent French scheme

Who may not be able to join:

  • Women who are currently pregnant or breastfeeding
  • Adults who are under a legal protection order, such as court protection, curatorship, or guardianship

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: +33142165724

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

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Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Institut National de la Santé Et de la Recherche Médicale, France
Registry
ClinicalTrials.gov
Start date
8 September 2022
Est. completion
30 September 2027

Where this trial is recruiting

🇫🇷 France

Primary endpoints

Skeletal muscle severity outcome; Cardiac muscle severity outcome; Protective structural variant outcome; Protective differential gene expression outcome; Protective 3D chromatin conformation outcome; Aggravating structural variant outcome; Aggravating differential gene expression outcome; Aggravating 3D chromatin conformation outcome outcome

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov