Long COVID Trial, Recruiting NCT05425264 Sponsor: VA Office of Research and Development Condition: Long COVID
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Long COVID Trial, Recruiting

NCT05425264
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are a Veteran.
  • You had a confirmed COVID-19 infection more than 90 days ago.
  • You have been diagnosed with at least 2 of the following conditions: high blood pressure, diabetes, heart disease, chronic kidney disease, or chronic obstructive pulmonary disease (a lung condition) — OR you have 1 of these conditions AND your body weight falls into the obese range (BMI over 30).

Who may not be able to join:

  • You had a heart attack within the last 3 months.
  • You have chest pain that happens during physical activity or is unpredictable and not well controlled.
  • You have severe heart failure, meaning your heart is pumping very poorly or you have significant symptoms at rest or with minimal activity (confirm with trial site).
  • Your blood pressure is very high and not controlled at the time of screening.
  • A recent heart tracing (ECG/EKG) shows signs of reduced blood flow to the heart, an irregular heartbeat, or a significant electrical blockage in the heart (confirm with trial site).
  • Your diabetes is poorly controlled, based on blood sugar or a blood test called HbA1C (confirm with trial site).
  • You are currently being treated for cancer (other than skin cancer) within the last 3 months.
  • You have a blood vessel condition in your legs that causes pain or cramping when you walk.
  • You have severe arthritis that makes it hard to walk.
  • You have a nerve or muscle condition that makes walking difficult, such as weakness requiring a walking aid or severe nerve damage.
  • You have advanced liver disease that is no longer manageable with treatment.
  • You are on dialysis due to kidney failure.
  • You have severe lung disease, such as needing oxygen at home or being admitted to hospital for breathing problems or pneumonia within the last month.
  • You are considered at high risk of falling, including a history of falls or broken bones.
  • You have dementia, as assessed during the consent process.
  • You have any other health condition that would make exercise testing or training unsafe (confirm with trial site).
  • You already exercise regularly, meaning structured aerobic activity more than 3 times per week.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Alice S. Ryan, PhD, Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD

Phone: (410) 605-7851

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
29 June 2023
Est. completion
30 January 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Change in VO2peak

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov