Phase 3 Leukaemia Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You have been diagnosed with a specific type of blood cancer called AML (but not the subtype called acute promyelocytic leukemia), as defined by current medical guidelines
• Your AML is classified as high-risk or intermediate-risk and is in first remission, OR your AML is in second remission regardless of risk level (partial remission may also be considered)
• You are planned to receive a stem cell transplant from a closely matched related or unrelated donor, or from a half-matched family donor using a specific type of stem cell collection
• Your planned pre-transplant treatment meets a certain intensity threshold (confirm with trial site)
• Your planned anti-rejection medication after transplant is based on a drug called tacrolimus
• You are between 18 and 75 years old
• You are in good general health and able to carry out everyday activities with little or no limitation (as measured by a standard medical scale)

Who may not be able to join:

• You are planned to use certain other anti-rejection medications, including cyclosporine, ATG, alemtuzumab, or abatacept
• You have been found to have a specific eye condition called macular edema during the screening process
• You have significant problems with your heart, lungs, liver, or kidneys
• Your liver is not functioning well enough, based on specific blood test results being too high
• Your kidneys are not filtering blood well enough, based on a standard calculation of kidney function
• You have diabetes
• You have a current or past history of an eye inflammation condition called uveitis
• You have a current or past history of macular edema (a swelling in the eye)

Important: Always verify eligibility with the trial site directly before applying.