Phase 1 Lung Cancer Trial, Recruiting NCT05452005 Sponsor: University of California, Davis Condition: Lung Cancer
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Phase 1 Lung Cancer Trial, Recruiting

NCT05452005
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults (men and women) aged 18 years or older
  • People who have been diagnosed with non-small cell lung cancer (a type of lung cancer) that has spread to the brain, confirmed by a biopsy — whether the brain tumors have already been treated or not
  • People whose treating doctor estimates they are likely to live for at least 3 more months
  • People who have stored tumor tissue samples available from a previous biopsy or surgery (tissue from a site where the cancer has spread is preferred if available)
  • People who are physically able to tolerate all study procedures, including lying still for 30 to 60 minutes during scans
  • People who are able to understand and willing to sign a consent form agreeing to take part in the study
  • People who are already planned to receive further cancer treatment followed by standard follow-up imaging scans
  • People who have had a specific type of scan called an FDG PET/CT within 21 days of joining the study
  • People who have had a brain MRI scan within 21 days of joining the study
  • People with a general health and activity level rated at 2 or below on a standard medical scale (meaning they are able to care for themselves but may not be able to do heavy physical work) (confirm with trial site)
  • People whose kidneys are functioning at a sufficient level, measured by a blood test result of 60 or above (confirm with trial site)

Who may not be able to join:

  • Women who are pregnant or currently breastfeeding
  • People who are currently incarcerated (prisoners)
  • People who have another type of cancer at the same time that could make the scan results difficult to interpret accurately
  • People who weigh more than 350 pounds (approximately 159 kg), as the PET/CT scanning equipment has a weight limit

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 19 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Julie L. Sutcliffe, PhD, The Regents of the University of California (Davis)

Phone: 916-734-5536

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Registry
ClinicalTrials.gov
Start date
13 September 2022
Est. completion
31 December 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

[18F]-αvβ6-BP PET/CT imaging compared to immunohistochemistry

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 19 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov