Chronic Kidney Disease Trial, Recruiting NCT05465044 Sponsor: VA Office of Research and Development Condition: Chronic Kidney Disease
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Chronic Kidney Disease Trial, Recruiting

NCT05465044
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are a Veteran aged 18 or older who has been diagnosed with end-stage kidney disease (kidney failure) and either will soon need to start regular dialysis, or have been on hemodialysis for no longer than 8 weeks at one of the six participating VA centers.
  • You meet specific medical criteria related to kidney function, including producing more than half a liter of urine per day and having a certain level of remaining kidney function (confirm with trial site for full details).
  • You are willing to be randomly assigned to either 2 or 3 dialysis sessions per week and follow whichever schedule you are assigned.
  • You are willing to attend check-up appointments at the dialysis unit or by video/phone call, scheduled mostly alongside your regular dialysis visits.
  • You agree to monthly (or more frequent) check-ins and interviews throughout the study, regardless of which dialysis schedule you are assigned to.
  • You meet at least 5 out of 9 additional medical criteria related to incremental dialysis eligibility (confirm with trial site for full details).

Who may not be able to join:

  • You have a serious terminal illness, such as advanced (stage 4) cancer that has spread, or you have entered hospice care, with a life expectancy of less than 6 months.
  • Your blood potassium level was found to be too high (above 6.0 mEq/L) at any point in the 4 weeks before the study was set to begin.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 14 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Kamyar Kalantar-Zadeh, MD PhD, VA Long Beach Healthcare System, Long Beach, CA

Phone: (562) 826-8000

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
1 April 2023
Est. completion
30 September 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Change over time in numeric scale of Health-Related Quality of Life (HRQOL) Physical Component Score (PCS) of SF36 questionnaire.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 14 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov