Coeliac Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You have been diagnosed with Median Arcuate Ligament Syndrome (MALS) after being reviewed by a specialist team (including a vascular surgeon, stomach/gut doctor, and imaging specialist) at one of two Dutch expert centres.
- You experience pain after eating, plus at least two of the following: changing what you eat to avoid pain, losing weight without trying, or having unexplained diarrhoea.
- Scans have shown a significant narrowing (70% or more) of a specific artery (the celiac artery) caused by a ligament pressing on it, confirmed by at least two different types of imaging, including a specific breathing-in and breathing-out CT scan.
- An abdominal ultrasound has not found other common conditions that could explain your symptoms.
- A camera examination of your stomach and upper small intestine showed no abnormalities, unless any changes found are related to reduced blood flow to the gut lining.
Who may not be able to join:
- You are not a suitable candidate for the keyhole (endoscopic) procedure to release the ligament — for example, because you have had previous surgery in that area of the body.
- You are pregnant.
- You have previously had a procedure (surgical or via a tube/wire through a blood vessel) on the arteries supplying your digestive organs.
- You have a significant narrowing in either of the other two main arteries that supply blood to your intestines (confirm with trial site).
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: RH Geelkerken, MD PHD, Medisch Spectrum Twente
Phone: +31 534872000
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
The number of patients with significant reduction in abdominal symptoms on a VAS scale; The number of patients with significant reduction in abdominal symptoms.
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.