Coeliac Disease

Who might be able to join this trial: - You are an adult who previously took part in a related study where you were given an experimental hookworm infection, and you also have celiac disease that is being managed through your diet. Who may not be able to join: - You are currently taking medications or receiving treatm...

**Who might be able to join this trial:** - You are a man or woman between 18 and 70 years old at the time of screening - You have been officially diagnosed with celiac disease, confirmed by an intestinal biopsy and a positive blood test for celiac disease, at least 12 months before the start of the study (the biopsy a...

Who might be able to join this trial: - Your body mass index (BMI) must be between 18 and 40 at the time of your screening appointment. - You must be willing to eat a gluten-free product and specially prepared products that simulate accidental gluten exposure as part of the study. - You must have been formally diagnose...

Who might be able to join this trial: - You have previously been diagnosed with celiac disease, confirmed through a gut tissue sample (biopsy) and a positive blood test for celiac disease - You carry a specific gene variant called HLA-DQ2.5 (a genetic marker linked to celiac disease) - You have been following a strict...

Who might be able to join this trial: - The baby must be a newborn or infant under 6 months old who has not yet started eating solid foods (only breast milk or formula). - The baby must have a close family member (such as a parent or sibling) who has been diagnosed with celiac disease confirmed by a biopsy. Who may no...

**Who might be able to join this trial:** - Your blood tests for certain antibodies related to celiac disease (anti-tissue transglutaminase and antiendomysium antibodies) have come back negative - A gut examination has shown that the lining of your small intestine is normal, with no damage to the tiny finger-like stru...

Who might be able to join this trial: - You have been diagnosed with non-celiac gluten sensitivity or non-celiac wheat sensitivity and are currently following a gluten-free diet. Who may not be able to join: - You have been diagnosed with celiac disease. - You have a wheat or gluten allergy that involves your immune s...

Who might be able to join this trial: - You are 18 years old or older - You are covered by social insurance (such as a health insurance or social security system) - You are able and willing to sign a consent form agreeing to take part in the trial Who may not be able to join: - You are currently pregnant - You are und...

Who might be able to join this trial: - You are 18 years of age or older - You have been referred to receive treatment for pain caused by chronic pancreatitis (long-term inflammation of the pancreas) Who may not be able to join: - You are under 18 years of age - You have not been diagnosed with chronic pancreatitis (l...

**Who might be able to join this trial:** - Newborn babies born at 36 weeks or later at a Sanford Health Hospital, whose mother is 18 or older and agreed to participate before active labor began, and who will have regular check-ups at a Sanford Clinic - Children under 6 years old who get their regular healthcare at a...

**Who might be able to join this trial:** - You have a pancreatic mass that looks like it could be cancer, or you have been diagnosed with pancreatic cancer in a specific part of the pancreas (the middle or left-side portion) - You have some level of abdominal or back pain that may be related to the mass - Your pain s...

**Who might be able to join this trial:** - You have been following a gluten-free diet for at least 4 weeks - You are willing to eat gluten as part of the research - (For the celiac disease group only) Your celiac disease has been confirmed through a blood test and/or a tissue sample (biopsy) **Who may not be able to...

**Who might be able to join this trial:** - You are between 18 and 75 years old - You have been diagnosed with stage III or IV ovarian cancer, fallopian tube cancer, or primary peritoneal cancer that has been confirmed by a pathology test, OR you have one of these cancers that has come back and is still responding to p...

**Who might be able to join this trial:** - You have been diagnosed with Median Arcuate Ligament Syndrome (MALS) after being reviewed by a specialist team (including a vascular surgeon, stomach/gut doctor, and imaging specialist) at one of two Dutch expert centres. - You experience pain after eating, plus at least two...

**Who might be able to join this trial:** - You must be 18 years of age or older. - You must have a medical reason that already requires a blood draw. - You must be willing to sign a consent form agreeing to take part. - If you have celiac disease, your diagnosis must have been confirmed following current medical guide...

**Who might be able to join this trial:** - You are between 18 and 75 years old - You have been diagnosed with celiac disease, confirmed by both a positive intestinal biopsy and a positive blood test (anti-tTG IgA) - You still have ongoing celiac disease symptoms (scoring above 40 on a celiac symptom questionnaire) eve...

**Who might be able to join this trial:** - (Groups 1 and 2) You have been diagnosed with coeliac disease or dermatitis herpetiformis (a skin condition linked to gluten sensitivity). - (Group 3) You are a friend or non-related family member of someone who has been diagnosed with coeliac disease or dermatitis herpetifor...

**Who might be able to join this trial:** - You are between 18 and 80 years old. - For the **healthy/control group**: You have never been told by a doctor that you have Celiac Disease, Ulcerative Colitis, Crohn's disease, Irritable Bowel Syndrome (IBS), Functional Dyspepsia, or Type 2 Diabetes. - For the **disease gro...

**Who might be able to join this trial:** - You are between 18 and 65 years old - You have not used any systemic (whole-body) treatments for psoriasis for at least 3 months before joining the study - Your blood tests show negative results for certain antibodies related to coeliac disease (confirm with trial site) - You...

**Who might be able to join this trial:** This trial has three separate groups, each with different requirements: **Gluten Challenge Group (people with celiac disease who eat gluten-free):** - You are between 18 and 75 years old - You were diagnosed with celiac disease by an intestinal biopsy at least 12 months ago -...

Who might be able to join this trial: - No specific requirements are listed for who can join (confirm with trial site) Who may not be able to join: - People who have been diagnosed with celiac disease (a condition where the immune system reacts to gluten) are not eligible Important: Always verify eligibility with the...

Who might be able to join this trial: - People who are currently eating a diet that contains gluten, have a blood test showing raised levels of a celiac disease antibody (called TGt-IgA) above the normal range, and have had an intestinal biopsy confirming celiac disease. - People whose intestinal biopsy results show a...

Who might be able to join this trial: - You are between 18 and 75 years old (any gender) - You have been diagnosed with celiac disease confirmed by a blood test and a small bowel tissue sample (biopsy) showing a specific level of intestinal damage - Your celiac disease diagnosis was made within 4 months of your first s...

**Who might be able to join this trial:** - You are 18 years of age or older - You have been diagnosed with pancreatic cancer that cannot be removed by surgery - You have ongoing tumor-related pain in the central abdomen that is constant and has no other clear cause, rated at least 3 out of 10 on a pain scale - You are...

Who might be able to join this trial: - You are between 18 and 65 years old. - Your blood tests show no signs of celiac disease-related antibodies (specific proteins the immune system makes in response to gluten). - You do not have damage to the lining of your small intestine (confirm with trial site), especially if yo...

**Who might be able to join this trial:** - You have been diagnosed with celiac disease, confirmed by both a blood test and a small bowel (intestinal) biopsy - You carry a specific gene type called HLA-DQ2.5, which is linked to celiac disease (confirm with trial site) - You are currently following a strict gluten-free...

Who might be able to join this trial: - You are between 6 months and 80 years old and have been diagnosed with Familial Mediterranean Fever (FMF) based on recognised medical classification guidelines. - You are able to understand and fill out questionnaires on your own, or, if you are a child, a parent or guardian can...

Who might be able to join this trial: - You are between 2 and 18 years old and have recently been diagnosed with celiac disease. Who may not be able to join: - You are allergic to fewer than 3 of the top 8 most common food allergens (such as milk, eggs, fish, shellfish, tree nuts, peanuts, wheat, or soybeans) (confirm...

**Who might be able to join this trial:** - You were diagnosed with celiac disease at the V. Buzzi Children's Hospital in Milan between January 2011 and December 2019 (dates within that range, not including January 2010 or December 2020 themselves) - Your diagnosis was made following recognized European guidelines for...

**Who might be able to join this trial:** - You were 18 years old or older when you were diagnosed with coeliac disease - You have been diagnosed with coeliac disease confirmed by intestinal damage (villous atrophy), a positive blood test, and you improved both in symptoms and blood test results after starting a gluten...

Who might be able to join this trial: - You are currently eating a regular, normal diet (not a special or restricted diet) Who may not be able to join: - No specific exclusion criteria have been listed for this trial (confirm with trial site) Important: Always verify eligibility with the trial site directly before ap...

Who might be able to join this trial: - You must be 18 years old or older when you sign up for the study. - You must be able and willing to provide a single urine sample and follow all study procedures. - You must be able to understand what the study involves, agree to take part, and be willing to sign a form allowing...

Who might be able to join this trial: - You are 18 years of age or older and have had weight-loss (bariatric) surgery performed using a keyhole (laparoscopic) technique - You are able and willing to sign an agreement to take part in the study Who may not be able to join: - You have a history of allergic reactions to m...

Who might be able to join this trial: - Children between 2 and 13 years old - Children who have been officially diagnosed with either type 1 diabetes or celiac disease, OR children who do not have type 1 diabetes, celiac disease, or certain related antibodies in their blood - A parent or guardian has given their writte...

**Who might be able to join this trial:** - Your body weight is in a healthy range for your height (specifically, your BMI is between 18 and 33) - You are willing to follow the study procedures and have signed a written consent form agreeing to take part - You were diagnosed with coeliac disease as a child, confirmed b...

**Who might be able to join this trial:** - You must be 18 years old or older with a confirmed diagnosis of celiac disease - You must have visible defects in your tooth enamel, such as weak or damaged enamel - You must have active tooth decay (cavities) - You must have reported experiencing sensitive teeth (pain or dis...

Who might be able to join this trial: - You are currently going through testing or assessment to find out whether you have celiac disease Who may not be able to join: - You are not willing or able to sign the consent form agreeing to take part in the trial Important: Always verify eligibility with the trial site dire...

Who might be able to join this trial: - You are an adult, which in most US states means aged 18 to 90 (aged 19–90 if you live in Alabama or Nebraska; aged 21–90 if you live in Mississippi or Puerto Rico). - You have read and signed a consent form agreeing to take part in the study, or if you have difficulty making deci...

**Who might be able to join this trial:** - You are between 18 and 75 years old - You have been diagnosed with a specific type of stomach cancer (gastric adenocarcinoma) or cancer at the junction where the esophagus meets the stomach, confirmed by a tissue biopsy - Your cancer is located in the upper part of the stoma...

Who might be able to join this trial: - You are 18 years old or older - You have been diagnosed with coeliac disease, confirmed by a blood test or a biopsy (a small tissue sample taken by a doctor) Who may not be able to join: - You are under 18 years old - You are unable to give written consent to take part in the tr...

**Who might be able to join this trial:** - You are willing and able to sign a consent form agreeing to take part in the trial - You are a man or woman aged between 18 and 80 years old (inclusive) - You were diagnosed with celiac disease confirmed by a biopsy, or — if biopsy records are unavailable — you had a specific...

**Who might be able to join this trial:** - You have been diagnosed with advanced cancer of the bile ducts, gallbladder, or pancreas, confirmed by a laboratory test on a tissue sample. - You have ongoing cancer-related pain that scores 4 or higher on a pain scale of 0–10, has lasted more than one week, and your doctors...

Who might be able to join this trial: - You are an adult between 18 and 65 years old who has been diagnosed with coeliac disease confirmed by a biopsy (a small tissue sample test) - A recent gut biopsy taken within the last 12 months shows that your coeliac disease is in remission (the gut lining has healed) - You have...

**Who might be able to join this trial:** - Your child is between 8 and 14 years old at the time of joining the study - Your child has been diagnosed with celiac disease following recognised diagnostic guidelines (ESPGHAN 2020 criteria) - Your child has been strictly following a gluten-free diet for at least 18 months...

**Who might be able to join this trial:** - You are between 18 and 75 years old - You are scheduled to have a camera examination of your throat, stomach, and upper small intestine (a scope procedure) because doctors suspect you may have celiac disease - Your body weight falls within a healthy-to-moderate range for you...

Who might be able to join this trial: - You must be 18 years old or older. - You must be scheduled to have a procedure to look inside your small bowel, either using a tiny swallowed camera (capsule endoscopy) or a flexible tube with a camera (endoscopy). Who may not be able to join: - You may not be able to join if yo...

Who might be able to join this trial: - You must be 18 years old or older - You are already scheduled to have a camera examination of your upper digestive system (a procedure where a thin tube with a camera is passed through your mouth to look at your stomach and small intestine) - You are willing and able to sign a co...

**Who might be able to join this trial:** - You have been diagnosed with celiac disease following current European guidelines, either based on symptoms or a tissue biopsy, and have been found to have low iron levels or iron-deficiency anemia. - You were between 8 and 18 years old (inclusive) when you were diagnosed wit...

**Who might be able to join this trial:** - You are between 18 and 65 years old - You have recently been diagnosed with celiac disease, confirmed through blood tests and a small bowel tissue sample (biopsy) - You have not yet started following a gluten-free diet - You are willing to follow a supervised gluten-free diet...

Who might be able to join this trial: - Children and teenagers between the ages of 5 and 18 who are receiving ongoing treatment at the UKJ (University Hospital Jena) for a long-term health condition, such as a heart defect present from birth, inflammatory bowel disease, celiac disease, or a rheumatic disease Who may n...